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DR3 regulates negative selection during thymocyte developmentGenetic control of programmed cell death during animal development.T cell-specific inhibition of multiple apoptotic pathways blocks negative selection and causes autoimmunityEssential role of PI3Kdelta and PI3Kgamma in thymocyte survival.Bad can act as a key regulator of T cell apoptosis and T cell development.Protein kinase B regulates T lymphocyte survival, nuclear factor kappaB activation, and Bcl-X(L) levels in vivoWithdrawal of IL-7 induces Bax translocation from cytosol to mitochondria through a rise in intracellular pH.Apoptosis in the development of the immune system.Asymmetric thymocyte death underlies the CD4:CD8 T-cell ratio in the adaptive immune systemBcl-2 regulation of the inositol 1,4,5-trisphosphate receptor and calcium signaling in normal and malignant lymphocytes: potential new target for cancer treatment.Themis1 enhances T cell receptor signaling during thymocyte development by promoting Vav1 activity and Grb2 stability.Infliximab treatment induces apoptosis of lamina propria T lymphocytes in Crohn's disease.The serine/threonine kinase LKB1 controls thymocyte survival through regulation of AMPK activation and Bcl-XL expression.TCR v(beta) repertoire restriction and lack of CDR3 conservation implicate TCR-superantigen interactions in promoting the clonal evolution of murine thymic lymphomas.Differential involvement of p38 MAP kinase pathway and Bax translocation in the mitochondria-mediated cell death in TCR- and dexamethasone-stimulated thymocytes.Overexpression of the antiapoptotic protein A1 promotes the survival of double positive thymocytes awaiting positive selection.Different Role of Apaf-1 in Positive Selection, Negative Selection and Death by Neglect in Foetal Thymic Organ Culture
P2860
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P2860
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
The action of Bax and bcl-2 on T cell selection
@ast
The action of Bax and bcl-2 on T cell selection
@en
type
label
The action of Bax and bcl-2 on T cell selection
@ast
The action of Bax and bcl-2 on T cell selection
@en
prefLabel
The action of Bax and bcl-2 on T cell selection
@ast
The action of Bax and bcl-2 on T cell selection
@en
P2093
P2860
P356
P1476
The action of Bax and bcl-2 on T cell selection
@en
P2093
P2860
P304
P356
10.1084/JEM.188.6.1125
P407
P50
P577
1998-09-01T00:00:00Z