Independent roles for IL-2 and GATA-3 in stimulating naive CD4+ T cells to generate a Th2-inducing cytokine environment
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GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiationTCR Signal Strength Alters T-DC Activation and Interaction Times and Directs the Outcome of DifferentiationT cell responses to antigen: hasty proposals resolved through long engagementsEarly signaling events that underlie fate decisions of naive CD4(+) T cells toward distinct T-helper cell subsetsCD4+ T Cell-derived Novel Peptide Thp5 Induces Interleukin-4 Production in CD4+ T Cells to Direct T Helper 2 Cell DifferentiationThe Immunomodulatory Functions of Diacylglycerol Kinase ζThe differential expression of IL-4 and IL-13 and its impact on type-2 immunityHistory of interleukin-4An updated view on transcription factor GATA3-mediated regulation of Th1 and Th2 cell differentiationTCR-dependent translational control of GATA-3 enhances Th2 differentiationAbsence of the adaptor protein Shb potentiates the T helper type 2 response in a mouse model of atopic dermatitisEnforced expression of GATA3 allows differentiation of IL-17-producing cells, but constrains Th17-mediated pathologyThe transcription factor GATA3 actively represses RUNX3 protein-regulated production of interferon-gammaDifferentiation of effector CD4 T cell populations (*)The Biology of Autoimmune Response in the Scurfy Mice that Lack the CD4+Foxp3+ Regulatory T-CellsGenetic control of the inflammatory T-cell response in regulatory T-cell deficient scurfy mice.Targeted deletion of HIF-1alpha gene in T cells prevents their inhibition in hypoxic inflamed tissues and improves septic mice survival.Digital NFATc2 activation per cell transforms graded T cell receptor activation into an all-or-none IL-2 expression.GATA3: a master of many trades in immune regulation.The common gamma chain cytokines interleukin (IL)-2 and IL-7 indirectly modulate blood fluke development via effects on CD4+ T cells.The signaling suppressor CIS controls proallergic T cell development and allergic airway inflammation.T-cell-receptor-dependent signal intensity dominantly controls CD4(+) T cell polarization In Vivo.Potential non-T cells source of interleukin-4 in food allergyMHCII-mediated dialog between group 2 innate lymphoid cells and CD4(+) T cells potentiates type 2 immunity and promotes parasitic helminth expulsion.Tenuous paths in unexplored territory: From T cell receptor signaling to effector gene expression during thymocyte selection.Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors.A simple theoretical framework for understanding heterogeneous differentiation of CD4+ T cells.Notch ligand delta-like 4 regulates development and pathogenesis of allergic airway responses by modulating IL-2 production and Th2 immunity.Antigen affinity and antigen dose exert distinct influences on CD4 T-cell differentiationInhibition of suppressive T cell factor 1 (TCF-1) isoforms in naive CD4+ T cells is mediated by IL-4/STAT6 signalingDendritic cells and B cells: unexpected partners in Th2 development.Proprotein convertase FURIN constrains Th2 differentiation and is critical for host resistance against Toxoplasma gondii.Lipid phosphatases identified by screening a mouse phosphatase shRNA library regulate T-cell differentiation and protein kinase B AKT signaling.The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.CD4 T cells: fates, functions, and faultsTranscriptional profiling reveals functional links between RasGrf1 and Pttg1 in pancreatic beta cells.Interleukin-10 production by Th1 cells requires interleukin-12-induced STAT4 transcription factor and ERK MAP kinase activation by high antigen dose.Requirement for the basic helix-loop-helix transcription factor Dec2 in initial TH2 lineage commitment.Itk: the rheostat of the T cell response.Foxp3-positive macrophages display immunosuppressive properties and promote tumor growth.
P2860
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P2860
Independent roles for IL-2 and GATA-3 in stimulating naive CD4+ T cells to generate a Th2-inducing cytokine environment
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Independent roles for IL-2 and ...... -inducing cytokine environment
@ast
Independent roles for IL-2 and ...... -inducing cytokine environment
@en
type
label
Independent roles for IL-2 and ...... -inducing cytokine environment
@ast
Independent roles for IL-2 and ...... -inducing cytokine environment
@en
prefLabel
Independent roles for IL-2 and ...... -inducing cytokine environment
@ast
Independent roles for IL-2 and ...... -inducing cytokine environment
@en
P2093
P2860
P356
P1476
Independent roles for IL-2 and ...... -inducing cytokine environment
@en
P2093
Hidehiro Yamane
Jinfang Zhu
William E Paul
P2860
P304
P356
10.1084/JEM.20051304
P407
P577
2005-09-01T00:00:00Z