Cellular FLICE-inhibitory protein is required for T cell survival and cycling
about
The Fas-associated death domain protein is required in apoptosis and TLR-induced proliferative responses in B cellsFADD and caspase-8 control the outcome of autophagic signaling in proliferating T cellsFLIP the Switch: Regulation of Apoptosis and Necroptosis by cFLIPT Cell Adolescence: Maturation Events Beyond Positive SelectionFLIP and the death effector domain familycFLIP overexpression in T cells in thymoma-associated myasthenia gravisAltered thymic selection by overexpressing cellular FLICE inhibitory protein in T cells causes lupus-like syndrome in a BALB/c but not C57BL/6 strainFas-associated death domain (FADD) is a negative regulator of T-cell receptor-mediated necroptosis.The complex interplay between autophagy, apoptosis, and necrotic signals promotes T-cell homeostasis.Life and death in the thymus--cell death signaling during T cell development.The regulation and role of c-FLIP in human Th cell differentiationNKAP is required for T cell maturation and acquisition of functional competencyPhysiological functions of caspases beyond cell death.Regulation of chemoresistance via alternative messenger RNA splicingCaspase-8 and c-FLIPL associate in lipid rafts with NF-kappaB adaptors during T cell activation.An essential role for c-FLIP in the efficient development of mature T lymphocytes.Caspases at the crossroads of immune-cell life and death.Caspases leave the beaten track: caspase-mediated activation of NF-kappaB.Apoptosis in the development of the immune system.Antigen-mediated T cell expansion regulated by parallel pathways of death.Transgenic Bcl-3 slows T cell proliferation.An insight into molecular mechanisms of human T helper cell differentiation.The proapoptotic factors Bax and Bak regulate T Cell proliferation through control of endoplasmic reticulum Ca(2+) homeostasisA role for cFLIP in B cell proliferation and stress MAPK regulationc-FLIP(S) reduces activation of caspase and NF-kappaB pathways and decreases T cell survivalThe c-FLIPL cleavage product p43FLIP promotes activation of extracellular signal-regulated kinase (ERK), nuclear factor κB (NF-κB), and caspase-8 and T cell survival.Participation of c-FLIP in NLRP3 and AIM2 inflammasome activation.Regulation of NF-κB signaling by caspases and MALT1 paracaspase.L-CBM signaling in lymphocyte development and functionProgrammed necrosis and autophagy in immune function.Functions of caspase 8: the identified and the mysterious.Cellular FLICE-Inhibitory Protein Regulates Tissue Homeostasis.C-FLIPL Modulated Wnt/β-Catenin Activation via Association with TIP49 Protein.cFLIPL Interrupts IRF3-CBP-DNA Interactions To Inhibit IRF3-Driven Transcription.Enzymatically active single chain caspase-8 maintains T-cell survival during clonal expansion.CD95 co-stimulation blocks activation of naive T cells by inhibiting T cell receptor signaling.FADD deficiency impairs early hematopoiesis in the bone marrow.The c-FLIP-NH2 terminus (p22-FLIP) induces NF-kappaB activation.The paracaspase MALT1 controls caspase-8 activation during lymphocyte proliferation.c-FLIP protects mature T lymphocytes from TCR-mediated killing.
P2860
Q24621785-A7EC0E7A-1C23-4478-9C1A-E99EE3552DA8Q24646372-73C45815-1934-48AF-B2CD-360BAE438810Q26773368-383CD04F-FF63-4344-99C0-C09908EA8A40Q26800949-9D816926-270A-48A9-BEE1-A1EA18A6E13FQ28297969-B71C15E6-3933-455E-A7D2-6889EAA105FBQ28389001-1FFAED3C-812D-40F6-B912-0FBAA16BD00EQ33653469-E299A9FF-EE19-4CF2-9F94-4CE3B7C2BD65Q34059345-E6C057A0-234A-4428-8873-B1A1714E02EEQ34252212-6EC6EADA-92FF-47F9-BE49-D27E5F8FD1D5Q34361180-ED248857-162E-4CC1-BB42-79E93A73EC7CQ35206314-676F2F71-FF5C-4F8A-9546-BE286569D272Q35213582-D296E3B4-B785-4BB6-A3B7-7C4E036F4600Q35222080-2AF9ECEE-70D7-486E-A6AE-E213EA374102Q35822883-07AAC030-BC8E-4DD9-9149-81C36905A31FQ35906438-B2B6217F-FAC9-4364-A6F4-69008F33C287Q36403284-1564BD84-C57C-4AED-8B72-C95F6647EB72Q36430147-24BE6780-6C2C-4B6F-BBA8-988BD911E5C4Q36450945-EC39BD38-F773-4BF0-942F-CC20FA8521D8Q36850158-628F5A03-9567-4A2E-8CE3-50E926D8C033Q36970979-6DFD309D-DC97-48D9-B195-3B71107CE251Q37140322-F8997961-BB4D-41F9-B5D8-8541A8947219Q37165356-28857783-4B53-461F-83DB-410950FD3816Q37271231-E3AEA958-091C-4E16-AA48-14DE2B1D221BQ37287191-3097533C-FAD8-433D-9D72-E7CDF99FAE44Q37374154-5453693F-40DC-4A99-976A-EA00FCE3E5ADQ37459250-A3E815FE-D2BA-44A6-8D8A-79F38E4614CFQ37578811-253C4B6C-16E9-4D00-8F37-9038D207158CQ37814066-D9B7633B-5329-4636-BE4D-5F060B4D6114Q37979179-8CB63F1B-6BF4-40AB-800C-12360E3F1F64Q38034272-8CFA7014-7788-4F91-9B03-5401CABE52F2Q38214149-68DC2D47-3A5D-4A52-B01D-9383E23092AAQ38544605-6485952E-4ECD-406A-A701-241FADE4BAE7Q38724048-07818DB3-1A9E-4118-8A83-7426D0FE96A3Q38762343-56A0A390-CA9E-46AC-A8FD-4BED4E461F36Q41828166-7049243B-72B4-4B20-929B-E90B75B060D8Q41963150-EB0B0907-DFCE-442F-BBFB-F3A6778473C5Q42224191-E96BE364-E0AA-4B61-8F2C-05F2339ACB7FQ42772785-069DF869-46B0-4AFA-B66A-D504437AD6F7Q43119003-DD0DBAD9-53B6-4A0B-85FC-9B25AF0D87EEQ43128850-2EC48EBF-EBC5-4FE3-9D40-67DF2A7F4EE6
P2860
Cellular FLICE-inhibitory protein is required for T cell survival and cycling
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Cellular FLICE-inhibitory protein is required for T cell survival and cycling
@ast
Cellular FLICE-inhibitory protein is required for T cell survival and cycling
@en
type
label
Cellular FLICE-inhibitory protein is required for T cell survival and cycling
@ast
Cellular FLICE-inhibitory protein is required for T cell survival and cycling
@en
prefLabel
Cellular FLICE-inhibitory protein is required for T cell survival and cycling
@ast
Cellular FLICE-inhibitory protein is required for T cell survival and cycling
@en
P2093
P2860
P50
P356
P1476
Cellular FLICE-inhibitory protein is required for T cell survival and cycling
@en
P2093
Alisha R Elford
Andrew Wakeham
Annick Itie You-Ten
Bénédicte Lemmers
Christine Mirtsos
Huey-Lan Huang
Madeleine Bonnard
Nien-Jung Chen
P2860
P304
P356
10.1084/JEM.20050118
P407
P577
2005-07-25T00:00:00Z