The c-FLIP-NH2 terminus (p22-FLIP) induces NF-kappaB activation.
about
Antioxidant c-FLIP inhibits Fas ligand-induced NF-kB activation in a phosphatidylinositol 3-kinase/Akt-dependent mannerThe Fas death signaling pathway connecting reactive oxygen species generation and FLICE inhibitory protein down-regulationS-nitrosylation of FLICE inhibitory protein determines its interaction with RIP1 and activation of NF-kappa BAn antiapoptotic protein, c-FLIPL, directly binds to MKK7 and inhibits the JNK pathwayElevated NF-kappaB responses and FLIP levels in leukemic but not normal lymphocytes: reduction by salicylate allows TNF-induced apoptosisRegulation of CD95/Fas signaling at the DISCRIPK-dependent necrosis and its regulation by caspases: a mystery in five actsMechanism of procaspase-8 activation by c-FLIPLMolecular architecture of the DED chains at the DISC: regulation of procaspase-8 activation by short DED proteins c-FLIP and procaspase-8 prodomainFLIP and the death effector domain familyAllogeneic transplantation, Fas signaling, and dysregulation of hepcidinFADD regulates NF-κB activation and promotes ubiquitination of cFLIPL to induce apoptosisc-FLIP, a master anti-apoptotic regulatorThe heme oxygenase-1 and c-FLIP in acute myeloid leukemias: two non-redundant but mutually exclusive cellular safeguards protecting cells against TNF-induced cell death?c-Flip overexpression affects satellite cell proliferation and promotes skeletal muscle agingInfected cell killing by HIV-1 protease promotes NF-kappaB dependent HIV-1 replication.HIV gp120 induces, NF-kappaB dependent, HIV replication that requires procaspase 8Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitmentThe linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death.Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF-κB and MAPK signalingBcl-2 inhibits the innate immune response during early pathogenesis of murine congenital muscular dystrophyModel-based dissection of CD95 signaling dynamics reveals both a pro- and antiapoptotic role of c-FLIPL.The TRAIL of oncogenes to apoptosis.Roles of c-FLIP in Apoptosis, Necroptosis, and Autophagy.FLIP: a novel regulator of macrophage differentiation and granulocyte homeostasisHBx-induced NF-κB signaling in liver cells is potentially mediated by the ternary complex of HBx with p22-FLIP and NEMO.Combination of arsenic and interferon-α inhibits expression of KSHV latent transcripts and synergistically improves survival of mice with primary effusion lymphomasFLIP regulation of HO-1 and TNF signalling in human acute myeloid leukemia provides a unique secondary anti-apoptotic mechanismFractional killing arises from cell-to-cell variability in overcoming a caspase activity thresholdTargeting the Anti-Apoptotic Protein c-FLIP for Cancer Therapy.Fas (CD95) induces macrophage proinflammatory chemokine production via a MyD88-dependent, caspase-independent pathwayUnc93b Induces Apoptotic Cell Death and Is Cleaved by Host and Enteroviral Proteases.On the TRAIL to successful cancer therapy? Predicting and counteracting resistance against TRAIL-based therapeutics.Cellular FLICE-like inhibitory protein (C-FLIP): a novel target for cancer therapy.Fas-induced pulmonary apoptosis and inflammation during indirect acute lung injury.TNFR1-dependent pulmonary apoptosis during ischemic acute kidney injury.Distinct Activation Mechanisms of NF-κB Regulator Inhibitor of NF-κB Kinase (IKK) by Isoforms of the Cell Death Regulator Cellular FLICE-like Inhibitory Protein (cFLIP).Kaposi sarcoma-associated herpesvirus/human herpesvirus 8 and lymphoproliferative disordersEpigenetic regulation of the TRAIL/Apo2L apoptotic pathway by histone deacetylase inhibitors: an attractive approach to bypass melanoma immunotherapy resistancec-FLIP knockdown induces ligand-independent DR5-, FADD-, caspase-8-, and caspase-9-dependent apoptosis in breast cancer cells.
P2860
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P2860
The c-FLIP-NH2 terminus (p22-FLIP) induces NF-kappaB activation.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
The c-FLIP-NH2 terminus (p22-FLIP) induces NF-kappaB activation.
@en
The c-FLIP-NH2 terminus
@nl
type
label
The c-FLIP-NH2 terminus (p22-FLIP) induces NF-kappaB activation.
@en
The c-FLIP-NH2 terminus
@nl
prefLabel
The c-FLIP-NH2 terminus (p22-FLIP) induces NF-kappaB activation.
@en
The c-FLIP-NH2 terminus
@nl
P2093
P2860
P356
P1476
The c-FLIP-NH2 terminus (p22-FLIP) induces NF-kappaB activation
@en
P2093
Alexander Golks
Inna N Lavrik
Peter H Krammer
P2860
P304
P356
10.1084/JEM.20051556
P407
P50
P577
2006-05-08T00:00:00Z