Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis.
about
Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cellsThe transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genesGeneration of pathogenic T(H)17 cells in the absence of TGF-β signallingTumor-specific Th17-polarized cells eradicate large established melanomaDysregulated T cell expression of TIM3 in multiple sclerosisAPC-derived cytokines and T cell polarization in autoimmune inflammationThe Mucosal Immune System and Its Regulation by AutophagyAdvances in T Helper 17 Cell Biology: Pathogenic Role and Potential Therapy in Multiple Sclerosisγδ T Cells and NK Cells - Distinct Pathogenic Roles as Innate-Like Immune Cells in CNS AutoimmunityStage-Specific Role of Interferon-Gamma in Experimental Autoimmune Encephalomyelitis and Multiple SclerosisThe regulation of inflammation by interferons and their STATsPouring fuel on the fire: Th17 cells, the environment, and autoimmunityJakpot! New small molecules in autoimmune and inflammatory diseasesDesign of oral agents for the management of multiple sclerosis: benefit and risk assessment for dimethyl fumarateT-bet represses T(H)17 differentiation by preventing Runx1-mediated activation of the gene encoding RORγtMarking and quantifying IL-17A-producing cells in vivoRTL551 treatment of EAE reduces CD226 and T-bet+ CD4 T cells in periphery and prevents infiltration of T-bet+ IL-17, IFN-γ producing T cells into CNSTumor necrosis factor-α produced in the kidney contributes to angiotensin II-dependent hypertension.IFN-gamma and STAT1 arrest monocyte migration and modulate RAC/CDC42 pathwaysIL-17 signaling-independent central nervous system autoimmunity is negatively regulated by TGF-beta.The role of the Th1 transcription factor T-bet in a mouse model of immune-mediated bone-marrow failureT-bet and eomesodermin play critical roles in directing T cell differentiation to Th1 versus Th17.More stories on Th17 cells.IFN-gamma regulates the requirement for IL-17 in proteoglycan-induced arthritis.Role of the innate immune system in the pathogenesis of multiple sclerosis.Mechanisms of intestinal inflammation and development of associated cancers: lessons learned from mouse models.Involvement of the janus kinase/signal transducer and activator of transcription signaling pathway in multiple sclerosis and the animal model of experimental autoimmune encephalomyelitis.Interferon-γ inhibits central nervous system myelination through both STAT1-dependent and STAT1-independent pathwaysBCL6 controls Th9 cell development by repressing Il9 transcription.Treatment with the antipsychotic agent, risperidone, reduces disease severity in experimental autoimmune encephalomyelitis.Th1 and Th17 cells: adversaries and collaboratorsInflammation programs self-reactive CD8+ T cells to acquire T-box-mediated effector function but does not prevent deletional toleranceCurrent views on the roles of Th1 and Th17 cells in experimental autoimmune encephalomyelitis.EAE mediated by a non-IFN-γ/non-IL-17 pathway.Interferon-β exacerbates Th17-mediated inflammatory disease.Transcriptional modulation of the immune response by peroxisome proliferator-activated receptor-{alpha} agonists in autoimmune disease.Characterization of autoreactive and bystander IL-17+ T cells induced in immunized C57BL/6 mice.Transcription factor T-bet regulates inflammatory arthritis through its function in dendritic cells.Exogenous IFN-gamma ex vivo shapes the alloreactive T-cell repertoire by inhibition of Th17 responses and generation of functional Foxp3+ regulatory T cellsDecreased signal transducers and activators of transcription (STAT) protein expression in lymphatic organs during EAE development in mice.
P2860
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P2860
Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Loss of T-bet, but not STAT1, ...... autoimmune encephalomyelitis.
@ast
Loss of T-bet, but not STAT1, ...... autoimmune encephalomyelitis.
@en
type
label
Loss of T-bet, but not STAT1, ...... autoimmune encephalomyelitis.
@ast
Loss of T-bet, but not STAT1, ...... autoimmune encephalomyelitis.
@en
prefLabel
Loss of T-bet, but not STAT1, ...... autoimmune encephalomyelitis.
@ast
Loss of T-bet, but not STAT1, ...... autoimmune encephalomyelitis.
@en
P2093
P2860
P356
P1476
Loss of T-bet, but not STAT1, ...... autoimmune encephalomyelitis.
@en
P2093
Brandon Sullivan
Estelle Bettelli
Laurie H Glimcher
Raymond A Sobel
Susanne J Szabo
Vijay K Kuchroo
P2860
P356
10.1084/JEM.20031819
P407
P577
2004-07-01T00:00:00Z