Pancreatic beta cell-specific expression of thioredoxin, an antioxidative and antiapoptotic protein, prevents autoimmune and streptozotocin-induced diabetes
about
Thioredoxin/Txnip: redoxisome, as a redox switch for the pathogenesis of diseasesThioredoxins, glutaredoxins, and peroxiredoxins--molecular mechanisms and health significance: from cofactors to antioxidants to redox signalingParadoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health ImplicationsNuclear and mitochondrial interaction involving mt-Nd2 leads to increased mitochondrial reactive oxygen species productionNAD(P)H oxidase and uncoupled nitric oxide synthase are major sources of glomerular superoxide in rats with experimental diabetic nephropathy.Exercise training with dietary counselling increases mitochondrial chaperone expression in middle-aged subjects with impaired glucose toleranceLow-dose radiation and its clinical implications: diabetes.Diabetic beta-cells can achieve self-protection against oxidative stress through an adaptive up-regulation of their antioxidant defenses.Inflammatory response in islet transplantation.Commonalities of genetic resistance to spontaneous autoimmune and free radical--mediated diabetes.Circulating thioredoxin suppresses lipopolysaccharide-induced neutrophil chemotaxis.Minireview: Thioredoxin-interacting protein: regulation and function in the pancreatic β-cell.Novel experimental strategies to prevent the development of type 1 diabetes mellitus.Regulatory roles of thioredoxin in oxidative stress-induced cellular responses.Redox regulation by thioredoxin superfamily; protection against oxidative stress and aging.Novel potential interacting partners of fibronectin in spontaneous animal model of interstitial cystitisUnusual resistance of ALR/Lt mouse beta cells to autoimmune destruction: role for beta cell-expressed resistance determinantsRedox regulation of stress signals: possible roles of dendritic stellate TRX producer cells (DST cell types).Oxidative stress and redox modulation potential in type 1 diabetes.Gene- and cell-based therapeutics for type I diabetes mellitus.NADPH oxidase deficiency regulates Th lineage commitment and modulates autoimmunity.Inhibition of adenylyl cyclase type 5 increases longevity and healthful aging through oxidative stress protectionThioredoxin binding protein (TBP)-2/Txnip and α-arrestin proteins in cancer and diabetes mellitus.The effect of Nrf2 pathway activation on human pancreatic islet cells.Distinct glucose-dependent stress responses revealed by translational profiling in pancreatic beta-cells.NOX2 deficiency protects against streptozotocin-induced beta-cell destruction and development of diabetes in mice.Amelioration of obesity, glucose intolerance, and oxidative stress in high-fat diet and low-dose streptozotocin-induced diabetic rats by combination consisting of "curcumin with piperine and quercetin"Genetically engineered islets and alternative sources of insulin-producing cells for treating autoimmune diabetes: quo vadis?The thioredoxin system in retroviral infection and apoptosis.Parameters for measurement of oxidative stress in diabetes mellitus: applicability of enzyme-linked immunosorbent assay for clinical evaluation.A20 inhibits cytokine-induced apoptosis and nuclear factor kappaB-dependent gene activation in islets.Transgenic expression of decoy receptor 3 protects islets from spontaneous and chemical-induced autoimmune destruction in nonobese diabetic mice.Oxygen sensing and redox signaling: the role of thioredoxin in embryonic development and cardiac diseases.Protective role of programmed death 1 ligand 1 (PD-L1)in nonobese diabetic mice: the paradox in transgenic models.Rodent models for investigating the dysregulation of immune responses in type 1 diabetes.Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes.Resveratrol alleviates cardiac dysfunction in streptozotocin-induced diabetes: Role of nitric oxide, thioredoxin, and heme oxygenase.Overexpression of inducible cyclic AMP early repressor inhibits transactivation of genes and cell proliferation in pancreatic beta cells.Inactivation of specific β cell transcription factors in type 2 diabetes.The role of thioredoxin 1 in the mycophenolic acid-induced apoptosis of insulin-producing cells
P2860
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P2860
Pancreatic beta cell-specific expression of thioredoxin, an antioxidative and antiapoptotic protein, prevents autoimmune and streptozotocin-induced diabetes
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Pancreatic beta cell-specific ...... treptozotocin-induced diabetes
@ast
Pancreatic beta cell-specific ...... treptozotocin-induced diabetes
@en
type
label
Pancreatic beta cell-specific ...... treptozotocin-induced diabetes
@ast
Pancreatic beta cell-specific ...... treptozotocin-induced diabetes
@en
prefLabel
Pancreatic beta cell-specific ...... treptozotocin-induced diabetes
@ast
Pancreatic beta cell-specific ...... treptozotocin-induced diabetes
@en
P2093
P2860
P356
P1476
Pancreatic beta cell-specific ...... treptozotocin-induced diabetes
@en
P2093
P2860
P304
P356
10.1084/JEM.188.8.1445
P407
P577
1998-10-01T00:00:00Z