A dimeric mutant of human pancreatic ribonuclease with selective cytotoxicity toward malignant cells.
about
Structural features for the mechanism of antitumor action of a dimeric human pancreatic ribonuclease variantA ribonuclease A variant with low catalytic activity but high cytotoxicitySecond generation antitumour human RNase: significance of its structural and functional features for the mechanism of antitumour actionA Ribonuclease Isolated from Wild Ganoderma Lucidum Suppressed Autophagy and Triggered Apoptosis in Colorectal Cancer CellsCancer chemotherapy--ribonucleases to the rescue.A nuclear-directed human pancreatic ribonuclease (PE5) targets the metabolic phenotype of cancer cells.Evasion of ribonuclease inhibitor as a determinant of ribonuclease cytotoxicityHuman anti-ErbB2 immunoagents--immunoRNases and compact antibodies.Structural and functional relationships of natural and artificial dimeric bovine ribonucleases: new scaffolds for potential antitumor drugs.Highly selective toxic and proapoptotic effects of two dimeric ribonucleases on thyroid cancer cells compared to the effects of doxorubicin.The role of electrostatic interactions in the antitumor activity of dimeric RNases.Antitumor activity and other biological actions of oligomers of ribonuclease A.Essential stations in the intracellular pathway of cytotoxic bovine seminal ribonuclease.Small Molecule-Induced Domain Swapping as a Mechanism for Controlling Protein Function and Assembly.Dimer formation by a "monomeric" protein.Cytotoxic mechanism of the ribotoxin alpha-sarcin. Induction of cell death via apoptosis.Endowing human pancreatic ribonuclease with toxicity for cancer cells.The nuclear transport capacity of a human-pancreatic ribonuclease variant is critical for its cytotoxicity.
P2860
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P2860
A dimeric mutant of human pancreatic ribonuclease with selective cytotoxicity toward malignant cells.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
A dimeric mutant of human panc ...... xicity toward malignant cells.
@ast
A dimeric mutant of human panc ...... xicity toward malignant cells.
@en
type
label
A dimeric mutant of human panc ...... xicity toward malignant cells.
@ast
A dimeric mutant of human panc ...... xicity toward malignant cells.
@en
prefLabel
A dimeric mutant of human panc ...... xicity toward malignant cells.
@ast
A dimeric mutant of human panc ...... xicity toward malignant cells.
@en
P2093
P2860
P356
P1476
A dimeric mutant of human panc ...... oxicity toward malignant cells
@en
P2093
D Spalletti-Cernia
G D'Alessio
J Matousek
P Laccetti
P2860
P304
P356
10.1073/PNAS.96.14.7768
P407
P577
1999-07-01T00:00:00Z