Ubiquitination of beta-arrestin links seven-transmembrane receptor endocytosis and ERK activation
about
Mahogunin ring finger-1 (MGRN1) E3 ubiquitin ligase inhibits signaling from melanocortin receptor by competition with GalphasBeta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2Mdm2 directs the ubiquitination of beta-arrestin-sequestered cAMP phosphodiesterase-4D5Nedd4 mediates agonist-dependent ubiquitination, lysosomal targeting, and degradation of the beta2-adrenergic receptorTranslocation of arrestin induced by human A(3) adenosine receptor ligands in an engineered cell line: comparison with G protein-dependent pathwaysBeta-arrestins and heterotrimeric G-proteins: collaborators and competitors in signal transductionNovel roles for the E3 ubiquitin ligase atrophin-interacting protein 4 and signal transduction adaptor molecule 1 in G protein-coupled receptor signaling.Viagra for your synapses: Enhancement of hippocampal long-term potentiation by activation of beta-adrenergic receptors.Beyond desensitization: physiological relevance of arrestin-dependent signaling.A high-content, live-cell, and real-time approach to the quantitation of ligand-induced β-Arrestin2 and Class A/Class B GPCR mobilization.Temporal profiling of orexin receptor-arrestin-ubiquitin complexes reveals differences between receptor subtypes.Regulation of protease-activated receptor signaling by post-translational modifications.β-Arrestin-mediated receptor trafficking and signal transductionArrestin development: emerging roles for beta-arrestins in developmental signaling pathwaysβ-Arrestin and dishevelled coordinate biased signaling.Non-canonical signaling of the PTH receptorUbiquitin-mediated regulation of endocytosis by proteins of the arrestin family.MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound β(2)-adrenergic receptorsMolecular basis of parathyroid hormone receptor signaling and trafficking: a family B GPCR paradigm.Ubiquitin-dependent regulation of G protein-coupled receptor trafficking and signalingUbiquitin-specific Protease 20 Regulates the Reciprocal Functions of β-Arrestin2 in Toll-like Receptor 4-promoted Nuclear Factor κB (NFκB) Activation.Role of ubiquitination in endocytic trafficking of G-protein-coupled receptors.Therapeutic potential of β-arrestin- and G protein-biased agonists.Divergent modes for cargo-mediated control of clathrin-coated pit dynamicsbeta-Arrestin mediates beta1-adrenergic receptor-epidermal growth factor receptor interaction and downstream signaling.Down-regulation of β-arrestin2 promotes tumour invasion and indicates poor prognosis of hepatocellular carcinomaEndosomes: a legitimate platform for the signaling train.Prognostic significance of USP33 in advanced colorectal cancer patients: new insights into β-arrestin-dependent ERK signaling.Custom-designed proteins as novel therapeutic tools? The case of arrestins.Functional relevance of biased signaling at the angiotensin II type 1 receptor.A tale of two sites: How ubiquitination of a G protein-coupled receptor is coupled to its lysosomal trafficking from distinct receptor domains.Endocytosis and signaling: cell logistics shape the eukaryotic cell plan.Roles of proteolysis in regulation of GPCR function.Mitogen-Activated Protein (MAP) Kinase Scaffolding Proteins: A Recount.Biased agonism: An emerging paradigm in GPCR drug discovery.Arrestins: Critical Players in Trafficking of Many GPCRs.Regulation of GPCR Trafficking by Ubiquitin.Ubiquitin-Related Roles of β-Arrestins in Endocytic Trafficking and Signal Transduction.Coagulation and non-coagulation effects of thrombin.GPCR desensitization: Acute and prolonged phases.
P2860
Q24314383-62FCD8B0-8B54-40A1-BBD3-0E6756A52A95Q24315023-F4984799-96CF-4B65-B91F-28761928C10FQ24316484-60078462-0098-4CF3-A242-ED7C372AB227Q24320318-BF5495B5-7668-4AE0-A68A-E5CB76F284C7Q24646643-4086A1F3-B5D3-4244-88BC-23D233BD2931Q24653656-68C6335F-42EB-48AF-A6F4-26C12115E66EQ30010172-D767F11B-5065-4456-927C-67251E2FDC55Q33678921-C673A44E-BAC0-491A-8535-49B7510E6243Q33890802-9F6EE15C-628F-4AD2-94F7-27A6069041CAQ34218573-29B7A933-8A88-4BF2-939B-028840CD6225Q34947494-F4E202DA-5F97-4FA3-95B7-B0A6AB009835Q35064562-63DE9C15-18D1-4554-9A5A-4D683D97D096Q35175384-97087FB5-B787-4087-9C7E-10CD810F899CQ35565885-42122EE8-5DAE-41FD-AD51-09FE7E828706Q35647627-82B8952D-2A76-491B-814E-2521878FB5A0Q36190508-513C7FEC-41BE-47B4-BE9B-B5C0311EF0ADQ36228675-06842030-28F9-476D-8B5F-A865AF2241BEQ36446593-3876242B-8D28-494F-8884-2F28DB5CFE88Q36599592-430C1331-3C95-4261-BF7B-2D636ABFF085Q36670706-0C69339D-43C3-4297-AF25-9E0E990E4AC8Q36755025-1F3C59E3-AC2B-467B-8F20-F94BAF651E8EQ36763812-D929C4B1-0868-4342-9C4B-6936F9AEB211Q36773331-32193C3F-3BD8-40DE-A22D-B461D919A3B7Q36887413-0014FB19-AD22-4BCD-A070-11CA9A9B2018Q37339073-6104CD34-DC4E-4700-B25B-9ECA0B5349AAQ37349092-AEC1E2CA-D8BE-4E7F-8540-9DBFE838E75DQ37394435-6BD2623E-E9AC-4470-A9D5-EBCD560B2E68Q37697146-9AB66402-20C8-4EE3-AB4B-C031653EB0C8Q37735949-43976548-227E-462E-B5C6-6C5227114749Q37863171-3037D284-FC37-47D9-8C02-EC61406090ABQ37951943-37A732A1-3BAD-4CFB-8F6F-C8423A8A64E6Q37980726-68A64463-DB84-4552-AB5E-96A09F7097AFQ38050189-28D2EBA2-DB97-4B03-B3C3-F41F1590C417Q38086019-AB3DDC16-3C6F-4529-BEAE-8F0ACF7A7BD0Q38440471-9E1054B5-BC40-49B7-A6B3-13295BD9A766Q38521129-114DE75C-3A5A-4081-801D-90D26E4F25D7Q38521133-6EC16326-1EA7-4C7D-8B80-B1C0C13A341AQ38704567-820D734B-6039-4E8F-9966-2C50536C8B48Q38924721-EE500012-2518-44CD-9FAA-101D08909CBAQ39110070-F17C107A-94AD-4B42-9FCF-7652A6DA5D7E
P2860
Ubiquitination of beta-arrestin links seven-transmembrane receptor endocytosis and ERK activation
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Ubiquitination of beta-arresti ...... endocytosis and ERK activation
@ast
Ubiquitination of beta-arresti ...... endocytosis and ERK activation
@en
type
label
Ubiquitination of beta-arresti ...... endocytosis and ERK activation
@ast
Ubiquitination of beta-arresti ...... endocytosis and ERK activation
@en
prefLabel
Ubiquitination of beta-arresti ...... endocytosis and ERK activation
@ast
Ubiquitination of beta-arresti ...... endocytosis and ERK activation
@en
P2093
P2860
P356
P1476
Ubiquitination of beta-arresti ...... endocytosis and ERK activation
@en
P2093
Kunhong Xiao
Larry S Barak
Magali Berthouze
Robert J Lefkowitz
Seungkirl Ahn
Sudha K Shenoy
P2860
P304
29549-29562
P356
10.1074/JBC.M700852200
P407
P577
2007-07-31T00:00:00Z