Inactivation and secondary structure in the D4/S4-5 region of the SkM1 sodium channel.
about
A1152D mutation of the Na+ channel causes paramyotonia congenita and emphasizes the role of DIII/S4-S5 linker in fast inactivationHelix-stabilizing effects of the pentapeptide KIFMK and its related peptides on the sodium channel inactivation gate peptides.A revised view of cardiac sodium channel "blockade" in the long-QT syndromeSize matters: Erythromelalgia mutation S241T in Nav1.7 alters channel gating.Charge immobilization of skeletal muscle Na+ channels: role of residues in the inactivation linkerA structural rearrangement in the sodium channel pore linked to slow inactivation and use dependence.Movement of voltage sensor S4 in domain 4 is tightly coupled to sodium channel fast inactivation and gating charge immobilizationParoxysmal extreme pain disorder M1627K mutation in human Nav1.7 renders DRG neurons hyperexcitableCharacterization of a novel Nav1.5 channel mutation, A551T, associated with Brugada syndrome.Paroxysmal extreme pain disorder mutations within the D3/S4-S5 linker of Nav1.7 cause moderate destabilization of fast inactivation.On mutations that uncouple sodium channel activation from inactivation.Lidocaine induces a slow inactivated state in rat skeletal muscle sodium channels.A human muscle Na+ channel mutation in the voltage sensor IV/S4 affects channel block by the pentapeptide KIFMK.Solution structures of the cytoplasmic linkers between segments S4 and S5 (S4-S5) in domains III and IV of human brain sodium channels in SDS micelles.Role of amino acid residues in transmembrane segments IS6 and IIS6 of the Na+ channel alpha subunit in voltage-dependent gating and drug block.Cooperative effect of S4-S5 loops in domains D3 and D4 on fast inactivation of the Na+ channel.
P2860
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P2860
Inactivation and secondary structure in the D4/S4-5 region of the SkM1 sodium channel.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Inactivation and secondary structure in the D4/S4-5 region of the SkM1 sodium channel.
@ast
Inactivation and secondary structure in the D4/S4-5 region of the SkM1 sodium channel.
@en
type
label
Inactivation and secondary structure in the D4/S4-5 region of the SkM1 sodium channel.
@ast
Inactivation and secondary structure in the D4/S4-5 region of the SkM1 sodium channel.
@en
prefLabel
Inactivation and secondary structure in the D4/S4-5 region of the SkM1 sodium channel.
@ast
Inactivation and secondary structure in the D4/S4-5 region of the SkM1 sodium channel.
@en
P2093
P2860
P356
P1476
Inactivation and secondary structure in the D4/S4-5 region of the SkM1 sodium channel.
@en
P2093
G N Filatov
R L Barchi
S D Kraner
T P Nguyen
P2860
P304
P356
10.1085/JGP.111.6.703
P577
1998-06-01T00:00:00Z