GCK-3, a newly identified Ste20 kinase, binds to and regulates the activity of a cell cycle-dependent ClC anion channel
about
Cloning and characterization of a new intestinal inflammation-associated colonic epithelial Ste20-related protein kinase isoformCrystal structure of domain-swapped STE20 OSR1 kinase domainBehavioral analysis of Ste20 kinase SPAK knockout mice.Characterization of SPAK and OSR1, regulatory kinases of the Na-K-2Cl cotransporter.A C-terminal domain in KCC2 confers constitutive K+-Cl- cotransport.Carboxy terminus splice variation alters ClC channel gating and extracellular cysteine reactivityThe WNKs: atypical protein kinases with pleiotropic actions.A structural perspective on ClC channel and transporter function.C. elegans STK39/SPAK ortholog-mediated inhibition of ClC anion channel activity is regulated by WNK-independent ERK kinase signalingMolecular physiology of SPAK and OSR1: two Ste20-related protein kinases regulating ion transport.Differential regulation of a CLC anion channel by SPAK kinase ortholog-mediated multisite phosphorylation.CLC anion channel regulatory phosphorylation and conserved signal transduction domainsSte20-type kinases: evolutionarily conserved regulators of ion transport and cell volume.GCN-2 dependent inhibition of protein synthesis activates osmosensitive gene transcription via WNK and Ste20 kinase signaling.Regulatory phosphorylation induces extracellular conformational changes in a CLC anion channelThe Caenorhabditis elegans Excretory System: A Model for Tubulogenesis, Cell Fate Specification, and PlasticityMolecular and genetic characterization of osmosensing and signal transduction in the nematode Caenorhabditis elegans.Identification of regulatory phosphorylation sites in a cell volume- and Ste20 kinase-dependent ClC anion channel.The WD40 repeat protein WDR-23 functions with the CUL4/DDB1 ubiquitin ligase to regulate nuclear abundance and activity of SKN-1 in Caenorhabditis elegansOSR1 and SPAK cooperatively modulate Sertoli cell support of mouse spermatogenesis.The voltage-gated anion channels encoded by clh-3 regulate egg laying in C. elegans by modulating motor neuron excitabilityPhosphoregulation of the Na-K-2Cl and K-Cl cotransporters by the WNK kinases.Physiological and molecular mechanisms of salt and water homeostasis in the nematode Caenorhabditis elegans.Unique gating properties of C. elegans ClC anion channel splice variants are determined by altered CBS domain conformation and the R-helix linker.WNK Kinases in Development and Disease.Putting the pieces together: a crystal clear window into CLC anion channel regulationCaenorhabditis elegans WNK-STE20 pathway regulates tube formation by modulating ClC channel activity.The Ste20 kinases SPAK and OSR1 travel between cells through exosomes.Altered gating and regulation of a carboxy-terminal ClC channel mutant expressed in the Caenorhabditis elegans oocyte.Role of CBS and Bateman Domains in Phosphorylation-Dependent Regulation of a CLC Anion Channel.Regulatory Conformational Coupling between CLC Anion Channel Membrane and Cytoplasmic Domains.Evolutionarily conserved WNK and Ste20 kinases are essential for acute volume recovery and survival after hypertonic shrinkage in Caenorhabditis elegans.CLC-3 chloride channels moderate long-term potentiation at Schaffer collateral-CA1 synapses.
P2860
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P2860
GCK-3, a newly identified Ste20 kinase, binds to and regulates the activity of a cell cycle-dependent ClC anion channel
description
2005 nî lūn-bûn
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2005年の論文
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年学术文章
@zh-my
2005年学术文章
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2005年學術文章
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2005年學術文章
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2005年學術文章
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name
GCK-3, a newly identified Ste2 ...... le-dependent ClC anion channel
@ast
GCK-3, a newly identified Ste2 ...... le-dependent ClC anion channel
@en
type
label
GCK-3, a newly identified Ste2 ...... le-dependent ClC anion channel
@ast
GCK-3, a newly identified Ste2 ...... le-dependent ClC anion channel
@en
prefLabel
GCK-3, a newly identified Ste2 ...... le-dependent ClC anion channel
@ast
GCK-3, a newly identified Ste2 ...... le-dependent ClC anion channel
@en
P2093
P2860
P356
P1476
GCK-3, a newly identified Ste2 ...... le-dependent ClC anion channel
@en
P2093
Jerod Denton
Kevin Strange
Rebecca Morrison
Xiaoyan Yin
P2860
P304
P356
10.1085/JGP.200409215
P50
P577
2005-02-01T00:00:00Z