Protein-folding homeostasis in the endoplasmic reticulum and nutritional regulation.
about
Unfolding anti-tumor immunity: ER stress responses sculpt tolerogenic myeloid cells in cancerTranslational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eIF2α.Suppression of heat shock protein 27 using OGX-427 induces endoplasmic reticulum stress and potentiates heat shock protein 90 inhibitors to delay castrate-resistant prostate cancer.Role of Endoplasmic Reticulum Stress in Learning and Memory Impairment and Alzheimer's Disease-Like Neuropathology in the PS19 and APPSwe Mouse Models of Tauopathy and Amyloidosis.A membrane-bound eIF2 alpha kinase located in endosomes is regulated by heme and controls differentiation and ROS levels in Trypanosoma cruzi.IRE1α-Dependent Decay of CReP/Ppp1r15b mRNA Increases Eukaryotic Initiation Factor 2α Phosphorylation and Suppresses Protein SynthesisA tutorial on oxidative stress and redox signaling with application to exercise and sedentariness.Insulin demand regulates β cell number via the unfolded protein response.C/EBPγ Is a Critical Regulator of Cellular Stress Response Networks through Heterodimerization with ATF4Assessment of the redox status in patients with metabolic syndrome and type 2 diabetes reveals great variationsActivation of GCN2 kinase by ribosome stalling links translation elongation with translation initiation.CHOP induces activating transcription factor 5 (ATF5) to trigger apoptosis in response to perturbations in protein homeostasis.General control nonderepressible 2 deletion predisposes to asparaginase-associated pancreatitis in mice.Endoplasmic reticulum oxidoreductin-1α (Ero1α) improves folding and secretion of mutant proinsulin and limits mutant proinsulin-induced endoplasmic reticulum stress.ATP increases within the lumen of the endoplasmic reticulum upon intracellular Ca2+ release.Vertical sleeve gastrectomy reduces blood pressure and hypothalamic endoplasmic reticulum stress in mice.Translational and posttranslational regulation of XIAP by eIF2α and ATF4 promotes ER stress-induced cell death during the unfolded protein response.Tyrosine kinase inhibitors as novel drugs for the treatment of diabetes.Protein transport into the human ER and related diseases, Sec61-channelopathies.Multiple Mechanisms of Unfolded Protein Response-Induced Cell DeathProtein misfolding, amyotrophic lateral sclerosis and guanabenz: protocol for a phase II RCT with futility design (ProMISe trial).The unfolded protein response in skeletal development and homeostasis.Protein kinase R(PKR)-like endoplasmic reticulum kinase (PERK) inhibitors: a patent review (2010-2015).Inhibition of the integrated stress response reverses cognitive deficits after traumatic brain injuryPolysome fractionation and analysis of mammalian translatomes on a genome-wide scale.Axonally synthesized ATF4 transmits a neurodegenerative signal across brain regions.Peroxiredoxin 4 improves insulin biosynthesis and glucose-induced insulin secretion in insulin-secreting INS-1E cells.An investigation of nutrient-dependent mRNA translation in Drosophila larvae.The CDK inhibitor p21 is a novel target gene of ATF4 and contributes to cell survival under ER stress.Protein Folding and the Challenges of Maintaining Endoplasmic Reticulum Proteostasis in Idiopathic Pulmonary Fibrosis.Quantitative proteomics identifies redox switches for global translation modulation by mitochondrially produced reactive oxygen species.The protein kinase PERK/EIF2AK3 regulates proinsulin processing not via protein synthesis but by controlling endoplasmic reticulum chaperones.
P2860
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P2860
Protein-folding homeostasis in the endoplasmic reticulum and nutritional regulation.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Protein-folding homeostasis in the endoplasmic reticulum and nutritional regulation.
@ast
Protein-folding homeostasis in the endoplasmic reticulum and nutritional regulation.
@en
type
label
Protein-folding homeostasis in the endoplasmic reticulum and nutritional regulation.
@ast
Protein-folding homeostasis in the endoplasmic reticulum and nutritional regulation.
@en
prefLabel
Protein-folding homeostasis in the endoplasmic reticulum and nutritional regulation.
@ast
Protein-folding homeostasis in the endoplasmic reticulum and nutritional regulation.
@en
P2860
P1476
Protein-folding homeostasis in the endoplasmic reticulum and nutritional regulation.
@en
P2860
P356
10.1101/CSHPERSPECT.A013177
P577
2012-12-01T00:00:00Z