PDGF, bFGF and IGF-I stimulate the proliferation of intervertebral disc cells in vitro via the activation of the ERK and Akt signaling pathways
about
Molecular mechanisms of biological aging in intervertebral discsThe challenge and advancement of annulus fibrosus tissue engineering.Senescent vs. non-senescent cells in the human annulus in vivo: cell harvest with laser capture microdissection and gene expression studies with microarray analysis.Wnt signaling activates Shh signaling in early postnatal intervertebral discs, and re-activates Shh signaling in old discs in the mouse.Platelet-derived growth factor-mediated induction of the synaptic plasticity gene Arc/Arg3.1.Insulin-like growth factor 1 synergizes with bone morphogenetic protein 7-mediated anabolism in bovine intervertebral disc cellsLeptin induces cyclin D1 expression and proliferation of human nucleus pulposus cells via JAK/STAT, PI3K/Akt and MEK/ERK pathways.Akt/PKB isoforms expression in the human lumbar herniated disc: correlation with clinical and MRI findings.Regenerative and immunogenic characteristics of cultured nucleus pulposus cells from human cervical intervertebral discsInduction of anterior gradient 2 (AGR2) plays a key role in insulin-like growth factor-1 (IGF-1)-induced breast cancer cell proliferation and migration.Effects of Tobacco Smoking on the Degeneration of the Intervertebral Disc: A Finite Element StudyPlatelet-rich plasma treatment in symptomatic patients with knee osteoarthritis: preliminary results in a group of active patients.Organotypic Cultures of Intervertebral Disc Cells: Responses to Growth Factors and Signaling Pathways Involved.Effect of bFGF on the MCF-7 Cell Cycle with CD44(+)/CD24(-): Promoting the G0/G1→G2/S Transition.Action of fibroblast growth factor-2 on the intervertebral discBiological impact of the fibroblast growth factor family on articular cartilage and intervertebral disc homeostasis.Development of a two-step protocol for culture expansion of human annulus fibrosus cells with TGF-β1 and FGF-2.Disc cell senescence in intervertebral disc degeneration: Causes and molecular pathways.Gastrointestinal growth factors and hormones have divergent effects on Akt activation.Cell signaling pathways related to pain receptors in the degenerated disk.Type II cGMP-dependent protein kinase inhibits activation of key members of the RTK family in gastric cancer cells.IGF-IR signaling in epithelial to mesenchymal transition and targeting IGF-IR therapy: overview and new insightsEnhancing intervertebral disc repair and regeneration through biology: platelet-rich plasma as an alternative strategy.Reconstruction of an in vitro niche for the transition from intervertebral disc development to nucleus pulposus regeneration.Mechanical loading of the intervertebral disc: from the macroscopic to the cellular level.Biologic treatment of mild and moderate intervertebral disc degeneration.Growth factors and platelet-rich plasma: promising biological strategies for early intervertebral disc degeneration.Basic fibroblast growth factor promotes melanocyte migration via activating PI3K/Akt-Rac1-FAK-JNK and ERK signaling pathways.PDGF-BB inhibits intervertebral disc cell apoptosis in vitro.Characterization of miRNA expression in human degenerative lumbar disks.Effect of constitutively active Ras overexpression on cell growth in recombinant Chinese hamster ovary cells.Exogenous and autocrine growth factors stimulate human intervertebral disc cell proliferation via the ERK and Akt pathways.Intervertebral disc cells as competent phagocytes in vitro: implications for cell death in disc degeneration.Introduction of hIGF-1 gene into bone marrow stromal cells and its effects on the cell's biological behaviors.The Natural Polyphenol Epigallocatechin Gallate Protects Intervertebral Disc Cells from Oxidative Stress.IGF-1 rescues human intervertebral annulus cells from in vitro stress-induced premature senescence.Efficacy of Platelet-Rich Plasma in Retarding Intervertebral Disc Degeneration: A Meta-Analysis of Animal Studies.The PI3K/Akt pathway: a critical player in intervertebral disc degeneration.Intervertebral disk tissue engineering using biphasic silk composite scaffolds.Whole Transcriptome Analysis of Notochord-Derived Cells during Embryonic Formation of the Nucleus Pulposus.
P2860
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P2860
PDGF, bFGF and IGF-I stimulate the proliferation of intervertebral disc cells in vitro via the activation of the ERK and Akt signaling pathways
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
PDGF, bFGF and IGF-I stimulate ...... ERK and Akt signaling pathways
@ast
PDGF, bFGF and IGF-I stimulate ...... ERK and Akt signaling pathways
@en
type
label
PDGF, bFGF and IGF-I stimulate ...... ERK and Akt signaling pathways
@ast
PDGF, bFGF and IGF-I stimulate ...... ERK and Akt signaling pathways
@en
prefLabel
PDGF, bFGF and IGF-I stimulate ...... ERK and Akt signaling pathways
@ast
PDGF, bFGF and IGF-I stimulate ...... ERK and Akt signaling pathways
@en
P2860
P1476
PDGF, bFGF and IGF-I stimulate ...... ERK and Akt signaling pathways
@en
P2093
Dimitris Kletsas
P2860
P2888
P304
P356
10.1007/S00586-007-0408-9
P577
2007-09-01T00:00:00Z