Disc cell senescence in intervertebral disc degeneration: Causes and molecular pathways.
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Advances and Prospects in Stem Cells for Cartilage Regeneration.ROS: Crucial Intermediators in the Pathogenesis of Intervertebral Disc Degeneration.Human nucleus pulposus intervertebral disc cells becoming senescent using different treatments exhibit a similar transcriptional profile of catabolic and inflammatory genes.Intervertebral Disk Degeneration and Repair.Oxygen-Sensing Nox4 Generates Genotoxic ROS to Induce Premature Senescence of Nucleus Pulposus Cells through MAPK and NF-κB Pathways.Spine-on-a-chip: Human annulus fibrosus degeneration model for simulating the severity of intervertebral disc degeneration.Functional self-assembled peptide scaffold inhibits tumor necrosis factor-alpha-induced inflammation and apoptosis in nucleus pulposus cells by suppressing nuclear factor-κB signaling.Caveolin‑1 regulates oxidative stress‑induced senescence in nucleus pulposus cells primarily via the p53/p21 signaling pathway in vitro.Anti-CENP-B and anti-TOPO-1-containing sera from systemic sclerosis-related diseases with Raynaud's phenomenon induce vascular endothelial cell senescence not via classical p53-p21 pathway.Rapamycin prevents the intervertebral disc degeneration via inhibiting differentiation and senescence of annulus fibrosus cells.Cyclic mechanical tension reinforces DNA damage and activates the p53-p21-Rb pathway to induce premature senescence of nucleus pulposus cells.Bedside to bench and back to bedside: Translational implications of targeted intervertebral disc therapeutics.ABCs of the degenerative spine.Quality Assessment of Surgical Disc Samples Discriminates Human Annulus Fibrosus and Nucleus Pulposus on Tissue and Molecular Level.Photobiomodulation of extracellular matrix enzymes in human nucleus pulposus cells as a potential treatment for intervertebral disk degeneration
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Disc cell senescence in intervertebral disc degeneration: Causes and molecular pathways.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 18 May 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Disc cell senescence in intervertebral disc degeneration: Causes and molecular pathways.
@en
Disc cell senescence in intervertebral disc degeneration: Causes and molecular pathways.
@nl
type
label
Disc cell senescence in intervertebral disc degeneration: Causes and molecular pathways.
@en
Disc cell senescence in intervertebral disc degeneration: Causes and molecular pathways.
@nl
prefLabel
Disc cell senescence in intervertebral disc degeneration: Causes and molecular pathways.
@en
Disc cell senescence in intervertebral disc degeneration: Causes and molecular pathways.
@nl
P2093
P2860
P921
P1433
P1476
Disc cell senescence in intervertebral disc degeneration: Causes and molecular pathways
@en
P2093
P2860
P304
P356
10.1080/15384101.2016.1152433
P5008
P577
2016-05-18T00:00:00Z