Disruption of the RIIbeta subunit of PKA reverses the obesity syndrome of Agouti lethal yellow mice.
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Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugsAssembly of allosteric macromolecular switches: lessons from PKANovel Isoform-Specific Interfaces Revealed by PKA RIIβ Holoenzyme StructuresStructure and Allostery of the PKA RII Tetrameric HoloenzymeSingle Turnover Autophosphorylation Cycle of the PKA RIIβ HoloenzymeProtein kinase A is a target for aging and the aging heart.Differentially regulated protein kinase A (PKA) activity in adipose tissue and liver is associated with resistance to diet-induced obesity and glucose intolerance in mice that lack PKA regulatory subunit type IIα.Lack of cAMP-response element-binding protein 1 in the hypothalamus causes obesity.Neuropeptide Y signaling modulates the expression of ethanol-induced behavioral sensitization in mice.Adiponectin inhibits lipolysis in mouse adipocytes.Hypothalamic PKA regulates leptin sensitivity and adiposity.cAMP/PKA signaling defects in tumors: genetics and tissue-specific pluripotential cell-derived lesions in human and mouse.Deficiency of the RIIβ subunit of PKA affects locomotor activity and energy homeostasis in distinct neuronal populations.Microarray analysis sheds light on the dedifferentiating role of agouti signal protein in murine melanocytes via the Mc1rProtein kinase A regulatory subunits in human adipose tissue: decreased R2B expression and activity in adipocytes from obese subjectsPhosphodiesterase inhibitor-dependent inverse agonism of agouti-related protein on melanocortin 4 receptor in sea bass (Dicentrarchus labrax)Local cAMP signaling in disease at a glanceAttenuation of age-related metabolic dysfunction in mice with a targeted disruption of the Cbeta subunit of protein kinase A.Obesity-associated sympathetic overactivity in children and adolescents: the role of catecholamine resistance in lipid metabolism.Melanocortin-induced PKA activation inhibits AMPK activity via ERK-1/2 and LKB-1 in hypothalamic GT1-7 cells.Human tau may modify glucocorticoids-mediated regulation of cAMP-dependent kinase and phosphorylated cAMP response element binding protein.Pertussis toxin-sensitive signaling of melanocortin-4 receptors in hypothalamic GT1-7 cells defines agouti-related protein as a biased agonist.Protein kinase cAMP-dependent regulatory type II beta (PRKAR2B) gene variants in antipsychotic-induced weight gain.Whole-genome resequencing reveals signatures of selection and timing of duck domestication.
P2860
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P2860
Disruption of the RIIbeta subunit of PKA reverses the obesity syndrome of Agouti lethal yellow mice.
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2008 nî lūn-bûn
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2008年の論文
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年學術文章
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name
Disruption of the RIIbeta subu ...... of Agouti lethal yellow mice.
@ast
Disruption of the RIIbeta subu ...... of Agouti lethal yellow mice.
@en
type
label
Disruption of the RIIbeta subu ...... of Agouti lethal yellow mice.
@ast
Disruption of the RIIbeta subu ...... of Agouti lethal yellow mice.
@en
altLabel
Disruption of the RII subunit ...... e of agouti lethal yellow mice
@en
prefLabel
Disruption of the RIIbeta subu ...... of Agouti lethal yellow mice.
@ast
Disruption of the RIIbeta subu ...... of Agouti lethal yellow mice.
@en
P2093
P2860
P356
P1476
Disruption of the RIIbeta subu ...... of Agouti lethal yellow mice.
@en
P2093
G Stanley McKnight
Linghai Yang
Maria A Sikorski
P2860
P304
P356
10.1073/PNAS.0710607105
P407
P577
2008-01-02T00:00:00Z