The endocytic adapter E-Syt2 recruits the p21 GTPase activated kinase PAK1 to mediate actin dynamics and FGF signalling
about
A mutation in mouse Pak1ip1 causes orofacial clefting while human PAK1IP1 maps to 6p24 translocation breaking points associated with orofacial cleftingThe ER/PM microdomain, PI(4,5)P₂ and the regulation of STIM1-Orai1 channel function.Loss of all 3 Extended Synaptotagmins does not affect normal mouse development, viability or fertilityMechanisms of FGF gradient formation during embryogenesis.Homeostatic regulation of the PI(4,5)P2-Ca(2+) signaling system at ER-PM junctions.The Extended-Synaptotagmins.Loss of Extended Synaptotagmins ESyt2 and ESyt3 does not affect mouse development or viability, but in vitro cell migration and survival under stress are affected.Extended Synaptotagmin Interaction with the Fibroblast Growth Factor Receptor Depends on Receptor Conformation, Not Catalytic Activity.Antibody-induced dimerization of FGFR1 promotes receptor endocytosis independently of its kinase activity.Triggered Ca2+ influx is required for extended synaptotagmin 1-induced ER-plasma membrane tethering.A large-scale analysis of alternative splicing reveals a key role of QKI in lung cancer.Unveiling physiological functions of extended synaptotagmins.Extended Synaptotagmin Localizes to Presynaptic ER and Promotes Neurotransmission and Synaptic Growth in Drosophila.
P2860
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P2860
The endocytic adapter E-Syt2 recruits the p21 GTPase activated kinase PAK1 to mediate actin dynamics and FGF signalling
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
@zh-hant
name
The endocytic adapter E-Syt2 r ...... in dynamics and FGF signalling
@ast
The endocytic adapter E-Syt2 r ...... in dynamics and FGF signalling
@en
type
label
The endocytic adapter E-Syt2 r ...... in dynamics and FGF signalling
@ast
The endocytic adapter E-Syt2 r ...... in dynamics and FGF signalling
@en
prefLabel
The endocytic adapter E-Syt2 r ...... in dynamics and FGF signalling
@ast
The endocytic adapter E-Syt2 r ...... in dynamics and FGF signalling
@en
P2093
P2860
P356
P1433
P1476
The endocytic adapter E-Syt2 r ...... in dynamics and FGF signalling
@en
P2093
Chelsea Herdman
François Guillou
Michel G Tremblay
Steve Jean
P2860
P304
P356
10.1242/BIO.2012968
P577
2012-06-12T00:00:00Z