Integrin alphaIIb promoter-targeted expression of gene products in megakaryocytes derived from retrovirus-transduced human hematopoietic cells.
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Megakaryocyte- and megakaryocyte precursor-related gene therapiesPrimary megakaryocytes reveal a role for transcription factor NF-E2 in integrin alpha IIb beta 3 signalingCorrection of murine Bernard-Soulier syndrome by lentivirus-mediated gene therapy.CRISPR/Cas9-mediated conversion of human platelet alloantigen allotypesGlanzmann thrombasthenia: state of the art and future directions.Factor IX ectopically expressed in platelets can be stored in alpha-granules and corrects the phenotype of hemophilia B mice.Platelets as delivery systems for disease treatmentsPlatelet gene therapy improves hemostatic function for integrin alphaIIbbeta3-deficient dogs.Platelet specific promoters are insufficient to express protease activated receptor 1 (PAR1) transgene in mouse platelets.Gene therapy for platelet disorders: studies with Glanzmann's thrombasthenia.Methods for genetic modification of megakaryocytes and platelets.Platelet-targeted gene therapy with human factor VIII establishes haemostasis in dogs with haemophilia A.High efficiency gene transfer to airways of mice using influenza hemagglutinin pseudotyped lentiviral vectors.Physiological and tissue-specific vectors for treatment of inherited diseases.Genetic engineering of platelets to neutralize circulating tumor cellsBiosynthesis of FVIII in megakaryocytic cells: improved production and biochemical characterization.Targeting platelet GPIbalpha transgene expression to human megakaryocytes and forming a complete complex with endogenous GPIbbeta and GPIX.Factor VIII ectopically targeted to platelets is therapeutic in hemophilia A with high-titer inhibitory antibodies.Therapeutic expression of the platelet-specific integrin, alphaIIbbeta3, in a murine model for Glanzmann thrombasthenia.Induction of megakaryocytes to synthesize and store a releasable pool of human factor VIII.Identification of a gene element essential for leukemia-specific expression of transgenes.Ultrafine carbon particles induce interleukin-8 gene transcription and p38 MAPK activation in normal human bronchial epithelial cells.
P2860
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P2860
Integrin alphaIIb promoter-targeted expression of gene products in megakaryocytes derived from retrovirus-transduced human hematopoietic cells.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Integrin alphaIIb promoter-tar ...... ced human hematopoietic cells.
@ast
Integrin alphaIIb promoter-tar ...... ced human hematopoietic cells.
@en
type
label
Integrin alphaIIb promoter-tar ...... ced human hematopoietic cells.
@ast
Integrin alphaIIb promoter-tar ...... ced human hematopoietic cells.
@en
prefLabel
Integrin alphaIIb promoter-tar ...... ced human hematopoietic cells.
@ast
Integrin alphaIIb promoter-tar ...... ced human hematopoietic cells.
@en
P2093
P2860
P356
P1476
Integrin alphaIIb promoter-tar ...... ced human hematopoietic cells.
@en
P2093
P2860
P304
P356
10.1073/PNAS.96.17.9654
P407
P577
1999-08-01T00:00:00Z