MHC class II proteins and disease: a structural perspective.
about
Identification of a novel HLA-DPB1 allele (DPB1*1902) by haplotype-specific extraction and nucleotide sequencingRole of plasmacytoid dendritic cells for aberrant class II expression in exocrine glands from estrogen-deficient mice of healthy backgroundCrystal structure of HLA-DP2 and implications for chronic beryllium diseaseThe human Major Histocompatibility Complex as a paradigm in genomics researchInterrogating the major histocompatibility complex with high-throughput genomicsThe genetics of complex cholestatic disordersRisk factors and primary prevention trials for type 1 diabetesPredominant occupation of the class I MHC molecule H-2Kwm7 with a single self-peptide suggests a mechanism for its diabetes-protective effect.A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritisAntigen Presentation, Autoantigens, and Immune Regulation in Multiple Sclerosis and Other Autoimmune DiseasesMolecular Interactions Governing Autoantigen Presentation in Type 1 DiabetesPredicting Hemagglutinin MHC-II Ligand Analogues in Anti-TNFα Biologics: Implications for Immunogenicity of Pharmaceutical ProteinsHigh-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitisNNAlign: a platform to construct and evaluate artificial neural network models of receptor-ligand interactions.A time transect of exomes from a Native American population before and after European contactGenomic structure of the horse major histocompatibility complex class II region resolved using PacBio long-read sequencing technology.Small organic compounds enhance antigen loading of class II major histocompatibility complex proteins by targeting the polymorphic P1 pocket.Anchor side chains of short peptide fragments trigger ligand-exchange of class II MHC moleculesA systematic assessment of MHC class II peptide binding predictions and evaluation of a consensus approachEffective detection of human leukocyte antigen risk alleles in celiac disease using tag single nucleotide polymorphismsAn extension to a statistical approach for family based association studies provides insights into genetic risk factors for multiple sclerosis in the HLA-DRB1 gene.Prediction of HLA-DQ8beta cell peptidome using a computational program and its relationship to autoreactive T cellsPrediction of the binding affinities of peptides to class II MHC using a regularized thermodynamic model.An automated framework for understanding structural variations in the binding grooves of MHC class II moleculesLimitations of Ab initio predictions of peptide binding to MHC class II moleculesInsights into the ancestral organisation of the mammalian MHC class II region from the genome of the pteropid bat, Pteropus alecto.Peptide binding predictions for HLA DR, DP and DQ moleculesTherapeutic enzyme deimmunization by combinatorial T-cell epitope removal using neutral driftPeptide binding prediction for the human class II MHC allele HLA-DP2: a molecular docking approach.HLA-DQ2 and -DQ8 signatures of gluten T cell epitopes in celiac diseaseHLA-DP2 binding prediction by molecular dynamics simulations.Associations of HLA-DP variants with hepatitis B virus infection in southern and northern Han Chinese populations: a multicenter case-control studyStructure-based selection of small molecules to alter allele-specific MHC class II antigen presentationThe human cancer antigen mesothelin is more efficiently presented to the mouse immune system when targeted to the DEC-205/CD205 receptor on dendritic cells.Peanut-allergic subjects and their peanut-tolerant siblings have large differences in peanut-specific IgG that are independent of HLA class II.Regulation of major histocompatibility complex class II gene expression, genetic variation and disease.Survey of major histocompatibility complex class II diversity in pig-tailed macaques.HLA-DP, HLA-DQ, and HLA-DR have different requirements for invariant chain and HLA-DM.Immune pathways for translating viral infection into chronic airway disease.Prediction of peptides binding to MHC class I and II alleles by temporal motif mining
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P2860
MHC class II proteins and disease: a structural perspective.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
MHC class II proteins and disease: a structural perspective.
@ast
MHC class II proteins and disease: a structural perspective.
@en
type
label
MHC class II proteins and disease: a structural perspective.
@ast
MHC class II proteins and disease: a structural perspective.
@en
prefLabel
MHC class II proteins and disease: a structural perspective.
@ast
MHC class II proteins and disease: a structural perspective.
@en
P2860
P356
P1476
MHC class II proteins and disease: a structural perspective.
@en
P2093
Christian Siebold
Jack L Strominger
P2860
P2888
P304
P356
10.1038/NRI1805
P577
2006-04-01T00:00:00Z
P6179
1044455988