Small organic compounds enhance antigen loading of class II major histocompatibility complex proteins by targeting the polymorphic P1 pocket.
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Enhancement of tumour-specific immune responses in vivo by 'MHC loading-enhancer' (MLE)The Possible Mechanism of Idiosyncratic Lapatinib-Induced Liver Injury in Patients Carrying Human Leukocyte Antigen-DRB1*07:01Creation of an engineered APC system to explore and optimize the presentation of immunodominant peptides of major allergensAnchor side chains of short peptide fragments trigger ligand-exchange of class II MHC moleculesCharacterization of structural features controlling the receptiveness of empty class II MHC molecules.Structure-based selection of small molecules to alter allele-specific MHC class II antigen presentationIn vivo enhancement of peptide display by MHC class II molecules with small molecule catalysts of peptide exchange.Enhancing tumor vaccines: catalyzing MHC class II peptide exchange.HLA-DM and HLA-DO, key regulators of MHC-II processing and presentation.Mechanistic understanding and significance of small peptides interaction with MHC class II molecules for therapeutic applications.Skin sensitizers in cosmetics and beyond: potential multiple mechanisms of action and importance of T-cell assays for in vitro screening.Major Histocompatibility Complex (MHC) Class I and MHC Class II Proteins: Conformational Plasticity in Antigen Presentation.MHC class II complexes sample intermediate states along the peptide exchange pathway.A cell-based high-throughput screening assay system for inhibitor compounds of antigen presentation by HLA class II moleculeIn Silico and In Vitro Analysis of Interaction between Ximelagatran and Human Leukocyte Antigen (HLA)-DRB1*07:01.The lymph as a pool of self-antigens.Structure-based selection of human metabolite binding P4 pocket of DRB1*15:01 and DRB1*15:03, with implications for multiple sclerosis.
P2860
Q28476101-193665D6-C4B5-4A2D-9EC1-B4089635A639Q28548544-A5DDDCEC-6FB8-4851-A6C1-477BE12D9888Q28829665-308982E6-BD43-4B07-9A4D-D13791367B66Q33324394-954D5543-B3FF-4E01-BC60-7E67373239CDQ33886577-55C8560E-6B1D-44DB-99D1-93C9EF8C1B7DQ34063488-7B769D9F-5902-497C-A9B2-39A513D3E5C4Q37224874-ABC51420-EC4D-4C73-AE33-22BD274B8709Q37682892-25EDA2D5-C81A-47F1-998B-9059FDBD5131Q38181859-36CEB179-9AE3-4461-8658-727950399EAFQ38869738-3D9A0AC8-3EA5-4B93-8CEC-64211DBB430DQ38888014-752F4525-3A60-471A-96A4-88942BEFAF08Q39214326-5FC8407C-10FA-42DE-896B-5F7EEA675737Q40482918-8B4CF844-F6CB-4C02-85D6-1B08E76F2595Q41782459-543D4069-AC2D-4D85-A349-3B59602DAABFQ42289978-A0C86CA9-E3EF-4EB0-B15C-0887325DC68FQ42672113-ABF41113-C09D-48DB-AB94-85F5B107954DQ48044178-6199B6A5-AC91-4142-926F-6FA7F7BCA460
P2860
Small organic compounds enhance antigen loading of class II major histocompatibility complex proteins by targeting the polymorphic P1 pocket.
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Small organic compounds enhanc ...... ing the polymorphic P1 pocket.
@ast
Small organic compounds enhanc ...... ing the polymorphic P1 pocket.
@en
type
label
Small organic compounds enhanc ...... ing the polymorphic P1 pocket.
@ast
Small organic compounds enhanc ...... ing the polymorphic P1 pocket.
@en
prefLabel
Small organic compounds enhanc ...... ing the polymorphic P1 pocket.
@ast
Small organic compounds enhanc ...... ing the polymorphic P1 pocket.
@en
P2093
P2860
P356
P1476
Small organic compounds enhanc ...... ing the polymorphic P1 pocket.
@en
P2093
Christian Freund
Dominik Rückerl
Günther Jung
Heiko Krämer
J Arvid Söderhäll
Katharina Dickhaut
Kirsten Falk
Maria Hofstätter
Olaf Rötzschke
Ronald Kühne
P2860
P304
38535-38542
P356
10.1074/JBC.M606437200
P407
P577
2006-09-27T00:00:00Z