Small organic compounds enhance antigen loading of class II major histocompatibility complex proteins by targeting the polymorphic P1 pocket.

Small organic compounds enhance antigen loading of class II major histocompatibility complex proteins by targeting the polymorphic P1 pocket.

Item
http://www.wikidata.org/entity/Q33258637
Enhancement of tumour-specific immune responses in vivo by 'MHC loading-enhancer' (MLE)The Possible Mechanism of Idiosyncratic Lapatinib-Induced Liver Injury in Patients Carrying Human Leukocyte Antigen-DRB1*07:01Creation of an engineered APC system to explore and optimize the presentation of immunodominant peptides of major allergensAnchor side chains of short peptide fragments trigger ligand-exchange of class II MHC moleculesCharacterization of structural features controlling the receptiveness of empty class II MHC molecules.Structure-based selection of small molecules to alter allele-specific MHC class II antigen presentationIn vivo enhancement of peptide display by MHC class II molecules with small molecule catalysts of peptide exchange.Enhancing tumor vaccines: catalyzing MHC class II peptide exchange.HLA-DM and HLA-DO, key regulators of MHC-II processing and presentation.Mechanistic understanding and significance of small peptides interaction with MHC class II molecules for therapeutic applications.Skin sensitizers in cosmetics and beyond: potential multiple mechanisms of action and importance of T-cell assays for in vitro screening.Major Histocompatibility Complex (MHC) Class I and MHC Class II Proteins: Conformational Plasticity in Antigen Presentation.MHC class II complexes sample intermediate states along the peptide exchange pathway.A cell-based high-throughput screening assay system for inhibitor compounds of antigen presentation by HLA class II moleculeIn Silico and In Vitro Analysis of Interaction between Ximelagatran and Human Leukocyte Antigen (HLA)-DRB1*07:01.The lymph as a pool of self-antigens.Structure-based selection of human metabolite binding P4 pocket of DRB1*15:01 and DRB1*15:03, with implications for multiple sclerosis.
P2860

Small organic compounds enhance antigen loading of class II major histocompatibility complex proteins by targeting the polymorphic P1 pocket.

Item
http://www.wikidata.org/entity/Q33258637
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Small organic compounds enhanc ...... ing the polymorphic P1 pocket.
@ast
Small organic compounds enhanc ...... ing the polymorphic P1 pocket.
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type
label
Small organic compounds enhanc ...... ing the polymorphic P1 pocket.
@ast
Small organic compounds enhanc ...... ing the polymorphic P1 pocket.
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prefLabel
Small organic compounds enhanc ...... ing the polymorphic P1 pocket.
@ast
Small organic compounds enhanc ...... ing the polymorphic P1 pocket.
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P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
Small organic compounds enhanc ...... ing the polymorphic P1 pocket.
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P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698