A molecular link between activation and inactivation of sodium channels.
about
State-dependent trapping of flecainide in the cardiac sodium channelFunctional characterization and cold sensitivity of T1313A, a new mutation of the skeletal muscle sodium channel causing paramyotonia congenita in humansSingle-channel properties of human NaV1.1 and mechanism of channel dysfunction in SCN1A-associated epilepsyThe hitchhiker's guide to the voltage-gated sodium channel galaxyStudies of alpha-helicity and intersegmental interactions in voltage-gated Na+ channels: S2D4.Sodium channel carboxyl-terminal residue regulates fast inactivation.K+ channel inactivation mediated by the concerted action of the cytoplasmic N- and C-terminal domains.Functional expression of the L-type calcium channel in mice skeletal muscle during prenatal myogenesis.State-dependent cocaine block of sodium channel isoforms, chimeras, and channels coexpressed with the beta1 subunit.The N terminus of a schistosome beta subunit regulates inactivation and current density of a Cav2 channel.Structure and function of voltage-gated sodium channels.Long QT syndrome, Brugada syndrome, and conduction system disease are linked to a single sodium channel mutationCharge immobilization of skeletal muscle Na+ channels: role of residues in the inactivation linkerInactivation defects caused by myotonia-associated mutations in the sodium channel III-IV linkerMolecular analysis of the putative inactivation particle in the inactivation gate of brain type IIA Na+ channels.Molecular analysis of potential hinge residues in the inactivation gate of brain type IIA Na+ channelsGlutamine substitution at alanine1649 in the S4-S5 cytoplasmic loop of domain 4 removes the voltage sensitivity of fast inactivation in the human heart sodium channelMolecular action of lidocaine on the voltage sensors of sodium channelsInteraction between the pore and a fast gate of the cardiac sodium channel.Sodium channel activation gating is affected by substitutions of voltage sensor positive charges in all four domainsSodium channel inactivation is altered by substitution of voltage sensor positive chargesMovement and crevices around a sodium channel S3 segment.A double tyrosine motif in the cardiac sodium channel domain III-IV linker couples calcium-dependent calmodulin binding to inactivation gatingOn mutations that uncouple sodium channel activation from inactivation.Enhancement of closed-state inactivation in long QT syndrome sodium channel mutation DeltaKPQ.Comparison of aconitine-modified human heart (hH1) and rat skeletal (mu1) muscle Na+ channels: an important role for external Na+ ions.Paramyotonia congenita mutations reveal different roles for segments S3 and S4 of domain D4 in hSkM1 sodium channel gating.A human muscle Na+ channel mutation in the voltage sensor IV/S4 affects channel block by the pentapeptide KIFMK.Activation of neurokinin 3 receptor increases Na(v)1.9 current in enteric neurons.Induction of pseudo-periodic oscillation in voltage-gated sodium channel properties is dependent on the duration of prolonged depolarization.Movement of the Na+ channel inactivation gate during inactivation.[EXPRESS] Nav1.7 is phosphorylated by Fyn tyrosine kinase which modulates channel expression and gating in a cell type-dependent manner.
P2860
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P2860
A molecular link between activation and inactivation of sodium channels.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
A molecular link between activation and inactivation of sodium channels.
@ast
A molecular link between activation and inactivation of sodium channels.
@en
type
label
A molecular link between activation and inactivation of sodium channels.
@ast
A molecular link between activation and inactivation of sodium channels.
@en
prefLabel
A molecular link between activation and inactivation of sodium channels.
@ast
A molecular link between activation and inactivation of sodium channels.
@en
P2093
P356
P1476
A molecular link between activation and inactivation of sodium channels.
@en
P2093
P304
P356
10.1085/JGP.106.4.641
P577
1995-10-01T00:00:00Z