Inhibition of SIRT6 in prostate cancer reduces cell viability and increases sensitivity to chemotherapeutics.
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Intracellular Mono-ADP-Ribosylation in Signaling and DiseaseCommon features of chromatin in aging and cancer: cause or coincidence?Interplay between sirtuins, MYC and hypoxia-inducible factor in cancer-associated metabolic reprogrammingSirtuins in metabolism, DNA repair and cancerA Chemical Biology Approach to Reveal Sirt6-targeted Histone H3 Sites in Nucleosomes.Sirtuins: guardians of mammalian healthspan.SIRT6 promotes COX-2 expression and acts as an oncogene in skin cancer.Cyclic AMP signaling reduces sirtuin 6 expression in non-small cell lung cancer cells by promoting ubiquitin-proteasomal degradation via inhibition of the Raf-MEK-ERK (Raf/mitogen-activated extracellular signal-regulated kinase/extracellular signal-Thromboxane A2 Receptor Stimulation Enhances Microglial Interleukin-1β and NO Biosynthesis Mediated by the Activation of ERK PathwayN-Acylethanolamines Bind to SIRT6Upregulation of SIRT6 predicts poor prognosis and promotes metastasis of non-small cell lung cancer via the ERK1/2/MMP9 pathway.Sirtuin 6 plays an oncogenic role and induces cell autophagy in esophageal cancer cells.Autophagy induction by SIRT6 is involved in oxidative stress-induced neuronal damage.SIRT6 expression is associated with poor prognosis and chemosensitivity in patients with non-small cell lung cancer.SIRT6: Novel Mechanisms and Links to Aging and Disease.Sirtuin 6 (SIRT6) Activity Assays.SIRT6 histone deacetylase functions as a potential oncogene in human melanoma.Depletion of SIRT6 enzymatic activity increases acute myeloid leukemia cells' vulnerability to DNA-damaging agents.Dual Effects of Resveratrol on Cell Death and Proliferation of Colon Cancer Cells.Aberrant SIRT6 expression contributes to melanoma growth: Role of the autophagy paradox and IGF-AKT signaling.Molecular Insights into the Interaction of RONS and Thieno[3,2-c]pyran Analogs with SIRT6/COX-2: A Molecular Dynamics Study.Downregulation of SIRT6 by miR-34c-5p is associated with poor prognosis and promotes colon cancer proliferation through inhibiting apoptosis via the JAK2/STAT3 signaling pathway.Low Rap1-interacting factor 1 and sirtuin 6 expression predict poor outcome in radiotherapy-treated Hodgkin lymphoma patients.SIRT6 Depletion Sensitizes Human Hepatoma Cells to Chemotherapeutics by Downregulating MDR1 Expression.SIRT6 overexpression induces apoptosis of nasopharyngeal carcinoma by inhibiting NF-κB signaling
P2860
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P2860
Inhibition of SIRT6 in prostate cancer reduces cell viability and increases sensitivity to chemotherapeutics.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Inhibition of SIRT6 in prostat ...... sitivity to chemotherapeutics.
@en
Inhibition of SIRT6 in prostat ...... sitivity to chemotherapeutics.
@nl
type
label
Inhibition of SIRT6 in prostat ...... sitivity to chemotherapeutics.
@en
Inhibition of SIRT6 in prostat ...... sitivity to chemotherapeutics.
@nl
prefLabel
Inhibition of SIRT6 in prostat ...... sitivity to chemotherapeutics.
@en
Inhibition of SIRT6 in prostat ...... sitivity to chemotherapeutics.
@nl
P2093
P2860
P1433
P1476
Inhibition of SIRT6 in prostat ...... sitivity to chemotherapeutics.
@en
P2093
Boshi Wang
Gang Huang
Jiaxiang Shao
Qian Reuben Xie
Tengyuan Liu
Tingting Zhang
Weiliang Xia
P2860
P2888
P304
P356
10.1007/S13238-013-3054-5
P577
2013-08-27T00:00:00Z