Administration of neutralizing antibodies to interleukin-6 (IL-6) reduces experimental autoimmune encephalomyelitis and is associated with elevated levels of IL-6 bioactivity in central nervous system and circulation
about
The inflammasome pyrin contributes to pertussis toxin-induced IL-1β synthesis, neutrophil intravascular crawling and autoimmune encephalomyelitisMyelin basic protein induces inflammatory mediators from primary human endothelial cells and blood-brain barrier disruption: implications for the pathogenesis of multiple sclerosisIL-6 induces regionally selective spinal cord injury in patients with the neuroinflammatory disorder transverse myelitis.Amyloid fibrils composed of hexameric peptides attenuate neuroinflammation.Sustained high levels of interleukin-6 contribute to the pathogenesis of enterovirus 71 in a neonate mouse modelAttenuation of Th1 effector cell responses and susceptibility to experimental allergic encephalomyelitis in histamine H2 receptor knockout mice is due to dysregulation of cytokine production by antigen-presenting cells.Astrocyte response to IFN-γ limits IL-6-mediated microglia activation and progressive autoimmune encephalomyelitis.Seeking balance: Potentiation and inhibition of multiple sclerosis autoimmune responses by IL-6 and IL-10.Therapeutic effects of systemic administration of chaperone αB-crystallin associated with binding proinflammatory plasma proteins.Sympathetic neurons can produce and respond to interleukin 6Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation.Microbial epitopes act as altered peptide ligands to prevent experimental autoimmune encephalomyelitisSustained TNF production by central nervous system infiltrating macrophages promotes progressive autoimmune encephalomyelitis.Amelioration of experimental autoimmune encephalomyelitis in IL-4Ralpha-/- mice implicates compensatory up-regulation of Th2-type cytokines.IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis.Astrocytic IL-6 Influences the Clinical Symptoms of EAE in MiceKLF4 modulates expression of IL-6 in dendritic cells via both promoter activation and epigenetic modification.MicroRNA-17 Modulates Regulatory T Cell Function by Targeting Co-regulators of the Foxp3 Transcription FactorTransforming growth factor beta is dispensable for the molecular orchestration of Th17 cell differentiation.IL-1β and IL-6 Are Highly Expressed in RF+IgE+ Systemic Lupus Erythematous SubtypeInterleukin-6, a major cytokine in the central nervous system.In vivo effects of Ginkgo biloba extract on interleukin-6 cytokine levels in patients with neurological disorders.CXCL1 can be regulated by IL-6 and promotes granulocyte adhesion to brain capillaries during bacterial toxin exposure and encephalomyelitis.Human ESC-derived MSCs outperform bone marrow MSCs in the treatment of an EAE model of multiple sclerosis.Some misconceptions about understanding autoimmunity through experiments with knockouts.The glucocorticoid receptor in recipient cells keeps cytokine secretion in acute graft-versus-host disease at bay.
P2860
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P2860
Administration of neutralizing antibodies to interleukin-6 (IL-6) reduces experimental autoimmune encephalomyelitis and is associated with elevated levels of IL-6 bioactivity in central nervous system and circulation
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
Administration of neutralizing ...... nervous system and circulation
@ast
Administration of neutralizing ...... nervous system and circulation
@en
type
label
Administration of neutralizing ...... nervous system and circulation
@ast
Administration of neutralizing ...... nervous system and circulation
@en
prefLabel
Administration of neutralizing ...... nervous system and circulation
@ast
Administration of neutralizing ...... nervous system and circulation
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P2093
P2860
P356
P1433
P1476
Administration of neutralizing ...... nervous system and circulation
@en
P2093
P2860
P2888
P304
P356
10.1007/BF03401894
P407
P577
1995-11-01T00:00:00Z