Design of protein switches based on an ensemble model of allostery
about
Engineering extrinsic disorder to control protein activity in living cells.Dual allosteric activation mechanisms in monomeric human glucokinase.The Structure of a Thermophilic Kinase Shapes Fitness upon Random Circular PermutationDevelopment of a cancer-marker activated enzymatic switch from the herpes simplex virus thymidine kinase.Allosteric Regulation in the Ligand Binding Domain of Retinoic Acid Receptorγ.Construction of Protein Switches by Domain Insertion and Directed Evolution.Solution NMR Spectroscopy for the Study of Enzyme Allostery.The interplay between effector binding and allostery in an engineered protein switch.Enzymatic protein switches built from paralogous input domains.De Novo Design of an Allosteric Metalloprotein Assembly with Strained Disulfide Bonds.Asymmetric configurations in a reengineered homodimer reveal multiple subunit communication pathways in protein allostery.The cell-wall active mannuronan C5-epimerases in the model brown alga Ectocarpus: From gene context to recombinant protein.Engineered control of enzyme structural dynamics and function.The Use of a β-lactamase-based Conductimetric Biosensor Assay to Detect Biomolecular Interactions.Glutamine Hydrolysis by Imidazole Glycerol Phosphate Synthase Displays Temperature Dependent Allosteric Activation.Creation of Antigen-Dependent β-Lactamase Fusion Protein Tethered by Circularly Permuted Antibody Variable Domains.Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble
P2860
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P2860
Design of protein switches based on an ensemble model of allostery
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
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2015年學術文章
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2015年學術文章
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name
Design of protein switches based on an ensemble model of allostery
@ast
Design of protein switches based on an ensemble model of allostery
@en
type
label
Design of protein switches based on an ensemble model of allostery
@ast
Design of protein switches based on an ensemble model of allostery
@en
prefLabel
Design of protein switches based on an ensemble model of allostery
@ast
Design of protein switches based on an ensemble model of allostery
@en
P2093
P2860
P356
P1476
Design of protein switches based on an ensemble model of allostery
@en
P2093
Abigail H Laurent
Jay H Choi
Vincent J Hilser
P2860
P2888
P356
10.1038/NCOMMS7968
P407
P577
2015-04-22T00:00:00Z