EUK-134, a synthetic superoxide dismutase and catalase mimetic, prevents oxidative stress and attenuates kainate-induced neuropathology
about
Mitochondrial involvement and oxidative stress in temporal lobe epilepsyOxidative stress and epilepsy: literature reviewTargeting the redox balance in inflammatory skin conditionsParadoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health ImplicationsActivation of NADPH oxidase and extracellular superoxide production in seizure-induced hippocampal damageHIF-1α is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endotheliumTreatment with the reactive oxygen species scavenger EUK-207 reduces lung damage and increases survival during 1918 influenza virus infection in miceThe abolishment of anesthesia-induced cognitive impairment by timely protection of mitochondria in the developing rat brain: the importance of free oxygen radicals and mitochondrial integrityFree radical signalling underlies inhibition of CaV3.2 T-type calcium channels by nitrous oxide in the pain pathway.Role of oxidative stress in epileptic seizures.Reversal of age-related learning deficits and brain oxidative stress in mice with superoxide dismutase/catalase mimetics.Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-βAn important Indian traditional drug of ayurveda jatamansi and its substitute bhootkeshi: chemical profiling and antioxidant activity.Nonthermal atmospheric pressure plasma enhances mouse limb bud survival, growth, and elongationProlonged hypoxia increases ROS signaling and RhoA activation in pulmonary artery smooth muscle and endothelial cells.Mitochondrial uncoupling protein-2 protects the immature brain from excitotoxic neuronal death.Catalytic antioxidants and neurodegenerationTyrosine nitration: localisation, quantification, consequences for protein function and signal transduction.Oxidative damage to RNA: mechanisms, consequences, and diseases.Development of lipophilic cations as therapies for disorders due to mitochondrial dysfunction.Therapeutics against mitochondrial oxidative stress in animal models of aging.Peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC1alpha) is a metabolic regulator of intestinal epithelial cell fate.Antioxidants as treatment for neurodegenerative disorders.Amyloid β-induced impairments in hippocampal synaptic plasticity are rescued by decreasing mitochondrial superoxideToll-like receptor 4-mediated nuclear factor kappa B activation is essential for sensing exogenous oxidants to propagate and maintain oxidative/nitrosative cellular stress.Oxidative stress in neurodegenerative diseases: therapeutic implications for superoxide dismutase mimetics.Superoxide dismutases in the lung and human lung diseases.Oxidative stress activates endothelial innate immunity via sterol regulatory element binding protein 2 (SREBP2) transactivation of microRNA-92aMitigation of radiation-induced lung injury by genistein and EUK-207.Novel synthetic SOD/catalase mimetics can mitigate capillary endothelial cell apoptosis caused by ionizing radiation.Striatal neuroprotection from neonatal hypoxia-ischemia in piglets by antioxidant treatment with EUK-134 or edaravone.Antioxidants as a preventive treatment for epileptic process: a review of the current status.Pathogenic factors in vascular dementia and Alzheimer's disease. Multiple actions of heparin that probably are beneficial.ROS constitute a convergence nexus in the development of IGF1 resistance and impaired wound healing in a rat model of type 2 diabetes.Chemistry-to-gene screens in Caenorhabditis elegans.Microglia play a role in ethanol-induced oxidative stress and apoptosis in developing hypothalamic neurons.Pivotal role of reactive oxygen species in differential regulation of lipopolysaccharide-induced prostaglandins production in macrophagesSIRT3 Blocks Aging-Associated Tissue Fibrosis in Mice by Deacetylating and Activating Glycogen Synthase Kinase 3β.A synthetic superoxide dismutase/catalase mimetic EUK-207 mitigates radiation dermatitis and promotes wound healing in irradiated rat skin.Synergistic effects of environmental risk factors and gene mutations in Parkinson's disease accelerate age-related neurodegeneration.
P2860
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P2860
EUK-134, a synthetic superoxide dismutase and catalase mimetic, prevents oxidative stress and attenuates kainate-induced neuropathology
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
EUK-134, a synthetic superoxid ...... kainate-induced neuropathology
@ast
EUK-134, a synthetic superoxid ...... kainate-induced neuropathology
@en
type
label
EUK-134, a synthetic superoxid ...... kainate-induced neuropathology
@ast
EUK-134, a synthetic superoxid ...... kainate-induced neuropathology
@en
prefLabel
EUK-134, a synthetic superoxid ...... kainate-induced neuropathology
@ast
EUK-134, a synthetic superoxid ...... kainate-induced neuropathology
@en
P2093
P2860
P356
P1476
EUK-134, a synthetic superoxid ...... kainate-induced neuropathology
@en
P2093
P2860
P304
P356
10.1073/PNAS.96.17.9897
P407
P577
1999-08-01T00:00:00Z