about
Structural basis of SUFU-GLI interaction in human Hedgehog signalling regulation.A heritable form of SMARCE1-related meningiomas with important implications for follow-up and family screening.Non-Canonical Hh Signaling in Cancer-Current Understanding and Future DirectionsA Comprehensive Review of Pediatric Tumors and Associated Cancer Predisposition Syndromes.A novel mutation of the FAT2 gene in spinal meningioma.Suppressor of fused (Sufu) represses Gli1 transcription and nuclear accumulation, inhibits glioma cell proliferation, invasion and vasculogenic mimicry, improving glioma chemo-sensitivity and prognosisGenetic profiling by single-nucleotide polymorphism-based array analysis defines three distinct subtypes of orbital meningiomaMultisite interaction with Sufu regulates Ci/Gli activity through distinct mechanisms in Hh signal transduction.Recent developments in brain tumor predisposing syndromes.Tumor-Derived Suppressor of Fused Mutations Reveal Hedgehog Pathway Interactions.The Hedgehog pathway: role in cell differentiation, polarity and proliferationExome sequencing on malignant meningiomas identified mutations in neurofibromatosis type 2 (NF2) and meningioma 1 (MN1) genes.I only have eye for ewe: the discovery of cyclopamine and development of Hedgehog pathway-targeting drugsARID1A and TERT promoter mutations in dedifferentiated meningioma.Targeting hedgehog signaling in cancer: research and clinical developments.Recurrent somatic mutations in POLR2A define a distinct subset of meningiomas.Suppressor of fused impedes Ci/Gli nuclear import by opposing Trn/Kapβ2 in Hedgehog signaling.Differential expression profiling of microRNAs in para-carcinoma, carcinoma and relapse human pancreatic cancer.Association of Genetic Predisposition With Solitary Schwannoma or Meningioma in Children and Young Adults.Genetic landscape of meningioma.Biophysical characterisation of the novel zinc binding property in Suppressor of Fused.Merkel Cell Carcinoma with a Suppressor of Fused (SUFU) Mutation: Case Report and Potential Therapeutic Implications.Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutationsMembers of the Rusc protein family interact with Sufu and inhibit vertebrate Hedgehog signaling.Loss-of-function mutations in SMARCE1 cause an inherited disorder of multiple spinal meningiomas.Hypomorphic Recessive Variants in SUFU Impair the Sonic Hedgehog Pathway and Cause Joubert Syndrome with Cranio-facial and Skeletal Defects.Progestin-associated shift of meningioma mutational landscape.A description of familial clustering of meningiomas in the Utah population.Loss of SMARCE1 expression is a specific diagnostic marker of clear cell meningioma: a comprehensive immunophenotypical and molecular analysis.Suppressor of fused controls cerebellar neuronal differentiation in a manner modulated by GLI3 repressor and Fgf15.Targeted next-generation sequencing for differential diagnosis of neurofibromatosis type 2, schwannomatosis, and meningiomatosis.Germline SMARCE1 mutations predispose to both spinal and cranial clear cell meningiomas.High incidence of activating TERT promoter mutations in meningiomas undergoing malignant progression.Activation of hedgehog signaling and its association with cisplatin resistance in ovarian epithelial tumors.Childhood cancer predisposition syndromes-A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology.Differential Cellular Responses to Hedgehog Signalling in Vertebrates-What is the Role of Competence?Molecular mechanisms of suppressor of fused in regulating the hedgehog signalling pathway.Multiple skin hamartomata: a possible novel clinical presentation of SUFU neoplasia syndrome.
P2860
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P2860
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Loss of SUFU function in familial multiple meningioma.
@ast
Loss of SUFU function in familial multiple meningioma.
@en
type
label
Loss of SUFU function in familial multiple meningioma.
@ast
Loss of SUFU function in familial multiple meningioma.
@en
prefLabel
Loss of SUFU function in familial multiple meningioma.
@ast
Loss of SUFU function in familial multiple meningioma.
@en
P2093
P2860
P50
P1476
Loss of SUFU function in familial multiple meningioma
@en
P2093
Anne Kiuru
Eevi Kaasinen
Jussi Taipale
Kari Vesanen
Mervi Aavikko
Pia Alhopuro
Pia Vahteristo
Silva Saarinen
Song-Ping Li
P2860
P304
P356
10.1016/J.AJHG.2012.07.015
P407
P577
2012-09-01T00:00:00Z