The small G protein H-Ras in the mesolimbic system is a molecular gateway to alcohol-seeking and excessive drinking behaviors
about
Intermittent ethanol access schedule in rats as a preclinical model of alcohol abuse.Nf1 regulates alcohol dependence-associated excessive drinking and gamma-aminobutyric acid release in the central amygdala in mice and is associated with alcohol dependence in humansIncreased behavioral responses to ethanol in Lmo3 knockout miceThe First Alcohol Drink Triggers mTORC1-Dependent Synaptic Plasticity in Nucleus Accumbens Dopamine D1 Receptor Neurons.Protein tyrosine phosphatase α in the dorsomedial striatum promotes excessive ethanol-drinking behaviors.mTORC1-dependent translation of collapsin response mediator protein-2 drives neuroadaptations underlying excessive alcohol-drinking behaviors.Alcohol modulation of G-protein-gated inwardly rectifying potassium channels: from binding to therapeutics.mTOR complex 1: a key player in neuroadaptations induced by drugs of abuse.Orbitofrontal Neuroadaptations and Cross-Species Synaptic Biomarkers in Heavy-Drinking Macaques.Molecular mechanisms underlying alcohol-drinking behavioursDependence-induced ethanol drinking and GABA neurotransmission are altered in Alk deficient mice.Prosapip1-Dependent Synaptic Adaptations in the Nucleus Accumbens Drive Alcohol Intake, Seeking, and Reward.Rab-3 and unc-18 interactions in alcohol sensitivity are distinct from synaptic transmission.Chronic intermittent ethanol exposure and withdrawal leads to adaptations in nucleus accumbens core postsynaptic density proteome and dendritic spines.Region specific activation of the AKT and mTORC1 pathway in response to excessive alcohol intake in rodents.Promising pharmacogenetic targets for treating alcohol use disorder: evidence from preclinical models.mTORC2 in the dorsomedial striatum of mice contributes to alcohol-dependent F-Actin polymerization, structural modifications, and consumption.Targeting the intracellular signaling "STOP" and "GO" pathways for the treatment of alcohol use disorders.
P2860
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P2860
The small G protein H-Ras in the mesolimbic system is a molecular gateway to alcohol-seeking and excessive drinking behaviors
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年學術文章
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name
The small G protein H-Ras in t ...... d excessive drinking behaviors
@ast
The small G protein H-Ras in t ...... d excessive drinking behaviors
@en
type
label
The small G protein H-Ras in t ...... d excessive drinking behaviors
@ast
The small G protein H-Ras in t ...... d excessive drinking behaviors
@en
prefLabel
The small G protein H-Ras in t ...... d excessive drinking behaviors
@ast
The small G protein H-Ras in t ...... d excessive drinking behaviors
@en
P2093
P2860
P1476
The small G protein H-Ras in t ...... d excessive drinking behaviors
@en
P2093
Amy W Lasek
Jeremie Neasta
Patricia H Janak
Sami Ben Hamida
Sebastien Carnicella
Viktor Kharazia
P2860
P304
15849-15858
P356
10.1523/JNEUROSCI.2846-12.2012
P407
P577
2012-11-01T00:00:00Z