Polyvalent cations constitute the voltage gating particle in human connexin37 hemichannels
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Gap junctionsMotifs in the permeation pathway of connexin channels mediate voltage and Ca (2+) sensingBiological and biophysical properties of vascular connexin channels.Structural determinants for the differences in voltage gating of chicken Cx56 and Cx45.6 gap-junctional hemichannels.Atomic force microscopy of Connexin40 gap junction hemichannels reveals calcium-dependent three-dimensional molecular topography and open-closed conformations of both the extracellular and cytoplasmic faces.Effect of transjunctional KCl gradients on the spermine inhibition of connexin40 gap junctionsVoltage-dependent conformational changes in connexin channelsRegulation of connexin hemichannels by monovalent cations.The gap junction cellular internet: connexin hemichannels enter the signalling limelightAssociation between C1019T polymorphism of the connexin37 gene and coronary heart disease in patients with in-stent restenosis.An MIP/AQP0 mutation with impaired trafficking and function underlies an autosomal dominant congenital lamellar cataract.Divalent cations regulate connexin hemichannels by modulating intrinsic voltage-dependent gating.Loop gating of connexin hemichannels involves movement of pore-lining residues in the first extracellular loop domain.The carboxyl terminal residues 220-283 are not required for voltage gating of a chimeric connexin32 hemichannel.The N terminus of connexin37 contains an alpha-helix that is required for channel function.An intact connexin N-terminus is required for function but not gap junction formationCalcium homeostasis modulator (CALHM) ion channels.Paracrine signaling through plasma membrane hemichannelsGap junction structure: unraveled, but not fully revealed.Connexin37 protects against atherosclerosis by regulating monocyte adhesion.Gating on the outside.Regulation of Cx45 hemichannels mediated by extracellular and intracellular calcium.Connexins in Cardiovascular and Neurovascular Health and Disease: Pharmacological Implications.
P2860
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P2860
Polyvalent cations constitute the voltage gating particle in human connexin37 hemichannels
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2004年の論文
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name
Polyvalent cations constitute ...... human connexin37 hemichannels
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Polyvalent cations constitute ...... human connexin37 hemichannels
@en
type
label
Polyvalent cations constitute ...... human connexin37 hemichannels
@ast
Polyvalent cations constitute ...... human connexin37 hemichannels
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prefLabel
Polyvalent cations constitute ...... human connexin37 hemichannels
@ast
Polyvalent cations constitute ...... human connexin37 hemichannels
@en
P2860
P356
P1476
Polyvalent cations constitute ...... human connexin37 hemichannels
@en
P2093
Dorothy A Hanck
Viviana M Berthoud
P2860
P304
P356
10.1085/JGP.200409023
P577
2004-11-01T00:00:00Z