Regulation of KCNQ2/KCNQ3 current by G protein cycling: the kinetics of receptor-mediated signaling by Gq.
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International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapyNeural KCNQ (Kv7) channelsPhosphoinositides: lipid regulators of membrane proteinsDual phosphorylations underlie modulation of unitary KCNQ K(+) channels by Src tyrosine kinaseSignal transduction pathway for the substance P-induced inhibition of rat Kir3 (GIRK) channelPhospholipase C in Living CellsCa2+/calmodulin disrupts AKAP79/150 interactions with KCNQ (M-Type) K+ channelsG protein subunit dissociation and translocation regulate cellular response to receptor stimulation.RGS2 expression predicts amyloid-β sensitivity, MCI and Alzheimer's disease: genome-wide transcriptomic profiling and bioinformatics data mining.Fitting K(V) potassium channels into the PIP(2) puzzle: Hille group connects dots between illustrious HH groups.Kinetics of M1 muscarinic receptor and G protein signaling to phospholipase C in living cellsKinetics of PIP2 metabolism and KCNQ2/3 channel regulation studied with a voltage-sensitive phosphatase in living cells.A genetically encoded tool kit for manipulating and monitoring membrane phosphatidylinositol 4,5-bisphosphate in intact cells.Identification by mass spectrometry and functional characterization of two phosphorylation sites of KCNQ2/KCNQ3 channels.The cannabinoid agonist WIN55,212-2 increases intracellular calcium via CB1 receptor coupling to Gq/11 G proteins.Ca2+-dependent desensitization of TRPV2 channels is mediated by hydrolysis of phosphatidylinositol 4,5-bisphosphate.Combined phosphoinositide and Ca2+ signals mediating receptor specificity toward neuronal Ca2+ channels.Multiscale model of dynamic neuromodulation integrating neuropeptide-induced signaling pathway activity with membrane electrophysiology.Ci-VSP is a depolarization-activated phosphatidylinositol-4,5-bisphosphate and phosphatidylinositol-3,4,5-trisphosphate 5'-phosphatase.Phosphoinositides regulate ion channels.Three-dimensional architecture of extended synaptotagmin-mediated endoplasmic reticulum-plasma membrane contact sites.Excitatory muscarinic modulation strengthens virtual nicotinic synapses on sympathetic neurons and thereby enhances synaptic gainElectrostatic interaction of internal Mg2+ with membrane PIP2 Seen with KCNQ K+ channels.Why biophysicists make models: quantifying modulation of the M currentUse of virtual cell in studies of cellular dynamics.Combinatorial augmentation of voltage-gated KCNQ potassium channels by chemical openers.Roles of GRK and PDE4 activities in the regulation of beta2 adrenergic signalingContribution of near-threshold currents to intrinsic oscillatory activity in rat medial entorhinal cortex layer II stellate cells.Target-specific PIP(2) signalling: how might it work?Quantitative properties and receptor reserve of the DAG and PKC branch of G(q)-coupled receptor signalingA carboxy-terminal inter-helix linker as the site of phosphatidylinositol 4,5-bisphosphate action on Kv7 (M-type) K+ channels.Control of plasma membrane lipid homeostasis by the extended synaptotagminsPIP2 is a necessary cofactor for ion channel function: how and why?Fluorescence changes reveal kinetic steps of muscarinic receptor-mediated modulation of phosphoinositides and Kv7.2/7.3 K+ channels.Affinity for phosphatidylinositol 4,5-bisphosphate determines muscarinic agonist sensitivity of Kv7 K+ channels.Optogenetic reporters: Fluorescent protein-based genetically encoded indicators of signaling and metabolism in the brainModulation of Kv7 channels and excitability in the brain.Chansporter complexes in cell signaling.Selective inhibition of Cav3.3 T-type calcium channels by Galphaq/11-coupled muscarinic acetylcholine receptors.A mechanism for different receptors coupled to the same G protein to generate different responses mediated by different second messengers.
P2860
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P2860
Regulation of KCNQ2/KCNQ3 current by G protein cycling: the kinetics of receptor-mediated signaling by Gq.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
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2004年學術文章
@zh-hant
name
Regulation of KCNQ2/KCNQ3 curr ...... ptor-mediated signaling by Gq.
@ast
Regulation of KCNQ2/KCNQ3 curr ...... ptor-mediated signaling by Gq.
@en
type
label
Regulation of KCNQ2/KCNQ3 curr ...... ptor-mediated signaling by Gq.
@ast
Regulation of KCNQ2/KCNQ3 curr ...... ptor-mediated signaling by Gq.
@en
prefLabel
Regulation of KCNQ2/KCNQ3 curr ...... ptor-mediated signaling by Gq.
@ast
Regulation of KCNQ2/KCNQ3 curr ...... ptor-mediated signaling by Gq.
@en
P2093
P2860
P356
P1476
Regulation of KCNQ2/KCNQ3 curr ...... ptor-mediated signaling by Gq.
@en
P2093
Bertil Hille
Byung-Chang Suh
Ken Mackie
Lisa F Horowitz
Wiebke Hirdes
P2860
P304
P356
10.1085/JGP.200409029
P577
2004-06-01T00:00:00Z