Progression of chronic liver inflammation and fibrosis driven by activation of c-JUN signaling in Sirt6 mutant mice - Wikidata - wikimedia - TriplyDB

Progression of chronic liver inflammation and fibrosis driven by activation of c-JUN signaling in Sirt6 mutant mice

Progression of chronic liver inflammation and fibrosis driven by activation of c-JUN signaling in Sirt6 mutant mice

http://www.wikidata.org/entity/Q36451932

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Interplay between sirtuins, MYC and hypoxia-inducible factor in cancer-associated metabolic reprogramming SIRTain regulators of premature senescence and accelerated aging Regulation of Akt signaling by sirtuins: its implication in cardiac hypertrophy and aging Sirtuins in epigenetic regulation Sirtuin deacylases: a molecular link between metabolism and immunity Sirt6 deficiency results in progression of glomerular injury in the kidney Role of thiazolidinediones, insulin sensitizers, in non-alcoholic fatty liver disease Emerging role of sirtuins on tumorigenesis: possible link between aging and cancer Pathogenesis and therapeutic approaches for non-alcoholic fatty liver disease Posttranslational modification of Sirt6 activity by peroxynitrite.NPC1L1 knockout protects against colitis-associated tumorigenesis in mice.p53-dependent SIRT6 expression protects Aβ42-induced DNA damage.Sirt6 cooperates with Blimp1 to positively regulate osteoclast differentiation.Hepatic SREBP-2 and cholesterol biosynthesis are regulated by FoxO3 and Sirt6 Protein inhibitor of activated STAT 4 (PIAS4) regulates pro-inflammatory transcription in hepatocytes by repressing SIRT1.Chromatin and beyond: the multitasking roles for SIRT6 Epigenetics in radiation-induced fibrosis.Sirt6 regulates dendritic cell differentiation, maturation, and function.SIRT6 deacetylates H3K18ac at pericentric chromatin to prevent mitotic errors and cellular senescence.Sirtuin SIRT6 suppresses cell proliferation through inhibition of Twist1 expression in non-small cell lung cancer.Sirtuin 6 attenuates periapical lesion propagation by modulating hypoxia-induced chemokine (C-C motif) ligand 2 production in osteoblasts.The ubiquitin ligase CHIP prevents SirT6 degradation through noncanonical ubiquitination.Inhibition of SIRT6 in prostate cancer reduces cell viability and increases sensitivity to chemotherapeutics.Regulation and Function of Extracellular Nicotinamide Phosphoribosyltransferase/Visfatin.Emerging roles of SIRT1 in fatty liver diseases.The histone deacetylase SIRT6 blocks myostatin expression and development of muscle atrophy.Sirtuin 6 inhibits epithelial to mesenchymal transition during idiopathic pulmonary fibrosis via inactivating TGF-β1/Smad3 signaling.SIRT6 regulates the cigarette smoke-induced signalling in rheumatoid arthritis synovial fibroblasts.The sirtuin 6 prevents angiotensin II-mediated myocardial fibrosis and injury by targeting AMPK-ACE2 signaling.Oxidative stress induces endothelial cell senescence via downregulation of Sirt6.Sirtuin 2 Deficiency Increases Bacterial Phagocytosis by Macrophages and Protects from Chronic Staphylococcal Infection.Emerging Roles of Sirtuin 6 in Alzheimer's Disease.Sirtuins and Accelerated Aging in Scleroderma.The Role of Sirt6 in Obesity and Diabetes.SIRT6 Acts as a Negative Regulator in Dengue Virus-Induced Inflammatory Response by Targeting the DNA Binding Domain of NF-κB p65.Sirt6 deficiency impairs corneal epithelial wound healing Metabolism in 'the driver's seat SIRT6 overexpression induces apoptosis of nasopharyngeal carcinoma by inhibiting NF-κB signaling

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Progression of chronic liver inflammation and fibrosis driven by activation of c-JUN signaling in Sirt6 mutant mice

http://www.wikidata.org/entity/Q36451932

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2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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2012年學術文章

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2012年學術文章

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Progression of chronic liver i ...... signaling in Sirt6 mutant mice

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Progression of chronic liver i ...... signaling in Sirt6 mutant mice

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JBC.M112.415182

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Journal of Biological Chemistry

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Progression of chronic liver i ...... signaling in Sirt6 mutant mice

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Bin Gao

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Chu-Xia Deng

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Cuiying Xiao

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Della Reynolds

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Howard A Young

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Ogyi Park

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Qiang Chen

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Rui-Hong Wang

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Takashi Maruyama

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Tyler J Lahusen

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P2860

SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity

SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells

SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span

SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation

A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint

SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress

The sirtuin SIRT6 regulates lifespan in male mice

A liver full of JNK: signaling in regulation of cell function and disease pathogenesis, and clinical approaches

Over expression of wild type or a catalytically dead mutant of Sirtuin 6 does not influence NFκB responses

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50

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Adeline Bertola

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