Progression of chronic liver inflammation and fibrosis driven by activation of c-JUN signaling in Sirt6 mutant mice
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Interplay between sirtuins, MYC and hypoxia-inducible factor in cancer-associated metabolic reprogrammingSIRTain regulators of premature senescence and accelerated agingRegulation of Akt signaling by sirtuins: its implication in cardiac hypertrophy and agingSirtuins in epigenetic regulationSirtuin deacylases: a molecular link between metabolism and immunitySirt6 deficiency results in progression of glomerular injury in the kidneyRole of thiazolidinediones, insulin sensitizers, in non-alcoholic fatty liver diseaseEmerging role of sirtuins on tumorigenesis: possible link between aging and cancerPathogenesis and therapeutic approaches for non-alcoholic fatty liver diseasePosttranslational modification of Sirt6 activity by peroxynitrite.NPC1L1 knockout protects against colitis-associated tumorigenesis in mice.p53-dependent SIRT6 expression protects Aβ42-induced DNA damage.Sirt6 cooperates with Blimp1 to positively regulate osteoclast differentiation.Hepatic SREBP-2 and cholesterol biosynthesis are regulated by FoxO3 and Sirt6Protein inhibitor of activated STAT 4 (PIAS4) regulates pro-inflammatory transcription in hepatocytes by repressing SIRT1.Chromatin and beyond: the multitasking roles for SIRT6Epigenetics in radiation-induced fibrosis.Sirt6 regulates dendritic cell differentiation, maturation, and function.SIRT6 deacetylates H3K18ac at pericentric chromatin to prevent mitotic errors and cellular senescence.Sirtuin SIRT6 suppresses cell proliferation through inhibition of Twist1 expression in non-small cell lung cancer.Sirtuin 6 attenuates periapical lesion propagation by modulating hypoxia-induced chemokine (C-C motif) ligand 2 production in osteoblasts.The ubiquitin ligase CHIP prevents SirT6 degradation through noncanonical ubiquitination.Inhibition of SIRT6 in prostate cancer reduces cell viability and increases sensitivity to chemotherapeutics.Regulation and Function of Extracellular Nicotinamide Phosphoribosyltransferase/Visfatin.Emerging roles of SIRT1 in fatty liver diseases.The histone deacetylase SIRT6 blocks myostatin expression and development of muscle atrophy.Sirtuin 6 inhibits epithelial to mesenchymal transition during idiopathic pulmonary fibrosis via inactivating TGF-β1/Smad3 signaling.SIRT6 regulates the cigarette smoke-induced signalling in rheumatoid arthritis synovial fibroblasts.The sirtuin 6 prevents angiotensin II-mediated myocardial fibrosis and injury by targeting AMPK-ACE2 signaling.Oxidative stress induces endothelial cell senescence via downregulation of Sirt6.Sirtuin 2 Deficiency Increases Bacterial Phagocytosis by Macrophages and Protects from Chronic Staphylococcal Infection.Emerging Roles of Sirtuin 6 in Alzheimer's Disease.Sirtuins and Accelerated Aging in Scleroderma.The Role of Sirt6 in Obesity and Diabetes.SIRT6 Acts as a Negative Regulator in Dengue Virus-Induced Inflammatory Response by Targeting the DNA Binding Domain of NF-κB p65.Sirt6 deficiency impairs corneal epithelial wound healingMetabolism in 'the driver's seatSIRT6 overexpression induces apoptosis of nasopharyngeal carcinoma by inhibiting NF-κB signaling
P2860
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P2860
Progression of chronic liver inflammation and fibrosis driven by activation of c-JUN signaling in Sirt6 mutant mice
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Progression of chronic liver i ...... signaling in Sirt6 mutant mice
@ast
Progression of chronic liver i ...... signaling in Sirt6 mutant mice
@en
type
label
Progression of chronic liver i ...... signaling in Sirt6 mutant mice
@ast
Progression of chronic liver i ...... signaling in Sirt6 mutant mice
@en
prefLabel
Progression of chronic liver i ...... signaling in Sirt6 mutant mice
@ast
Progression of chronic liver i ...... signaling in Sirt6 mutant mice
@en
P2093
P2860
P356
P1476
Progression of chronic liver i ...... signaling in Sirt6 mutant mice
@en
P2093
Chu-Xia Deng
Cuiying Xiao
Della Reynolds
Howard A Young
Qiang Chen
Rui-Hong Wang
Takashi Maruyama
Tyler J Lahusen
P2860
P304
41903-41913
P356
10.1074/JBC.M112.415182
P407
P577
2012-10-16T00:00:00Z