Functional signatures in antiviral T-cell immunity for monitoring virus-associated diseases.
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Enumeration of functional T-cell subsets by fluorescence-immunospot defines signatures of pathogen burden in tuberculosisHuman CD8 T lymphocytes recognize Mycobacterium tuberculosis antigens presented by HLA-E during active tuberculosis and express type 2 cytokinesWnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cellsWhole-blood flow-cytometric analysis of antigen-specific CD4 T-cell cytokine profiles distinguishes active tuberculosis from non-active statesPredominance of heterosubtypic IFN-γ-only-secreting effector memory T cells in pandemic H1N1 naive adults.Polyfunctional responses by human T cells result from sequential release of cytokines.HLA Class I-T cell epitopes from trans-sialidase proteins reveal functionally distinct subsets of CD8+ T cells in chronic Chagas disease.T-cell immunity to infection with dengue virus in humans.Perforin and IL-2 upregulation define qualitative differences among highly functional virus-specific human CD8 T cellsPerforin expression directly ex vivo by HIV-specific CD8 T-cells is a correlate of HIV elite control.Regulatory T cells differentially modulate the maturation and apoptosis of human CD8+ T-cell subsets.Proliferation capacity and cytotoxic activity are mediated by functionally and phenotypically distinct virus-specific CD8 T cells defined by interleukin-7R{alpha} (CD127) and perforin expression.Chlamydia pneumoniae-induced memory CD4+ T-cell activation in human peripheral blood correlates with distinct antibody response patternsLensfree holographic imaging of antibody microarrays for high-throughput detection of leukocyte numbers and function.Early and prolonged antiretroviral therapy is associated with an HIV-1-specific T-cell profile comparable to that of long-term non-progressorsAlloantigen expression on non-hematopoietic cells reduces graft-versus-leukemia effects in mice.IL-2 production correlates with effector cell differentiation in HIV-specific CD8+ T cells.Multidimensional analysis of the frequencies and rates of cytokine secretion from single cells by quantitative microengraving.EBV-specific CD8+ T cells from asymptomatic pediatric thoracic transplant patients carrying chronic high EBV loads display contrasting features: activated phenotype and exhausted functionDiverse specificities, phenotypes, and antiviral activities of cytomegalovirus-specific CD8+ T cells.Anti-HPV16 E2 protein T-cell responses and viral control in women with usual vulvar intraepithelial neoplasia and their healthy partners.HIV vaccines: lessons learned and the way forward.Micropatterning of Aptamer Beacons to Create Cytokine-Sensing SurfacesHeterogeneous memory T cells in antiviral immunity and immunopathologyCharacterization of CD4 and CD8 T cell responses in MuSK myasthenia gravis.Evaluation of the diagnostic potential of IP-10 and IL-2 as biomarkers for the diagnosis of active and latent tuberculosis in a BCG-vaccinated populationComplementarity-determining region 3 size spectratypes of T cell receptor beta chains in CD8+ T cells following antiviral treatment of chronic hepatitis BPhenotypic and functional profiling of CD4 T cell compartment in distinct populations of healthy adults with different antigenic exposurePD-1 expression and IL-2 loss of cytomegalovirus- specific T cells correlates with viremia and reversible functional anergy.Persistent gamma-herpesvirus infection induces a CD4 T cell response containing functionally distinct effector populations.Effects of blood transportation on human peripheral mononuclear cell yield, phenotype and function: implications for immune cell biobanking.Antigen-specific CD4 T cells are induced after intravesical BCG-instillation therapy in patients with bladder cancer and show similar cytokine profiles as in active tuberculosisOvernight resting of PBMC changes functional signatures of antigen specific T- cell responses: impact for immune monitoring within clinical trials.Profiling T cell activation using single-molecule fluorescence in situ hybridization and flow cytometry.Functional capacity of Mycobacterium tuberculosis-specific T cell responses in humans is associated with mycobacterial loadThe frequencies of IFNγ+IL2+TNFα+ PPD-specific CD4+CD45RO+ T-cells correlate with the magnitude of the QuantiFERON® gold in-tube response in a prospective study of healthy indian adolescentsImmuno-hybridization chain reaction for enhancing detection of individual cytokine-secreting human peripheral mononuclear cellsDiagnosing latent tuberculosis in high-risk individuals: rising to the challenge in high-burden areas.Immunodiagnosis of tuberculosis: a dynamic view of biomarker discoveryMicropatterned aptasensors for continuous monitoring of cytokine release from human leukocytes.
P2860
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P2860
Functional signatures in antiviral T-cell immunity for monitoring virus-associated diseases.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Functional signatures in antiv ...... ing virus-associated diseases.
@ast
Functional signatures in antiv ...... ing virus-associated diseases.
@en
type
label
Functional signatures in antiv ...... ing virus-associated diseases.
@ast
Functional signatures in antiv ...... ing virus-associated diseases.
@en
prefLabel
Functional signatures in antiv ...... ing virus-associated diseases.
@ast
Functional signatures in antiv ...... ing virus-associated diseases.
@en
P2860
P356
P1476
Functional signatures in antiv ...... ring virus-associated diseases
@en
P2860
P304
P356
10.1038/NRI1840
P577
2006-05-01T00:00:00Z