A point mutation in the two-component regulator PhoP-PhoR accounts for the absence of polyketide-derived acyltrehaloses but not that of phthiocerol dimycocerosates in Mycobacterium tuberculosis H37Ra.
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Evolutionary landscape of the Mycobacterium tuberculosis complex from the viewpoint of PhoPR: implications for virulence regulation and application to vaccine developmentConsequences of genomic diversity in Mycobacterium tuberculosisStructure of the Response Regulator PhoP from Mycobacterium tuberculosis Reveals a Dimer through the Receiver DomainControl of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoPPapA3 is an acyltransferase required for polyacyltrehalose biosynthesis in Mycobacterium tuberculosisPhosphorylation of PhoP protein plays direct regulatory role in lipid biosynthesis of Mycobacterium tuberculosisProkaryotic ubiquitin-like protein (Pup) proteome of Mycobacterium tuberculosis [corrected]The changes in mycolic acid structures caused by hadC mutation have a dramatic effect on the virulence of Mycobacterium tuberculosis.PhoP: a missing piece in the intricate puzzle of Mycobacterium tuberculosis virulence.Genetic basis of virulence attenuation revealed by comparative genomic analysis of Mycobacterium tuberculosis strain H37Ra versus H37RvNovel genome polymorphisms in BCG vaccine strains and impact on efficacy.SMRT genome assembly corrects reference errors, resolving the genetic basis of virulence in Mycobacterium tuberculosis.Contrasting transcriptional responses of a virulent and an attenuated strain of Mycobacterium tuberculosis infecting macrophagesInteractions of attenuated Mycobacterium tuberculosis phoP mutant with human macrophages.Deciphering sulfoglycolipids of Mycobacterium tuberculosis.Variation among genome sequences of H37Rv strains of Mycobacterium tuberculosis from multiple laboratories.Evolutionary history of tuberculosis shaped by conserved mutations in the PhoPR virulence regulatorA specific polymorphism in Mycobacterium tuberculosis H37Rv causes differential ESAT-6 expression and identifies WhiB6 as a novel ESX-1 componentCharacterization of a novel ArsR-like regulator encoded by Rv2034 in Mycobacterium tuberculosisBiosynthesis and translocation of unsulfated acyltrehaloses in Mycobacterium tuberculosis.Identification of DNA binding motifs of the Mycobacterium tuberculosis PhoP/PhoR two-component signal transduction system.The cell envelope glycoconjugates of Mycobacterium tuberculosisGenetics of Capsular Polysaccharides and Cell Envelope (Glyco)lipids.Evaluation of mycobacterial virulence using rabbit skin liquefaction modelAdaptation to environmental stimuli within the host: two-component signal transduction systems of Mycobacterium tuberculosis.Mycobacterial glycolipids di-O-acylated trehalose and tri-O-acylated trehalose downregulate inducible nitric oxide synthase and nitric oxide production in macrophages.A common mechanism of inhibition of the Mycobacterium tuberculosis mycolic acid biosynthetic pathway by isoxyl and thiacetazoneStructural basis of DNA sequence recognition by the response regulator PhoP in Mycobacterium tuberculosisGenomic research for important pathogenic bacteria in China.Progress in targeting cell envelope biogenesis in Mycobacterium tuberculosis.A Nonsense Mutation in Mycobacterium marinum That Is Suppressible by a Novel MechanismAdvances In Mycobacterium Tuberculosis Therapeutics Discovery Utlizing Structural Biology.Biosynthesis of mycobacterial lipids by polyketide synthases and beyond.Strategies for desymmetrising trehalose to synthesise trehalose glycolipids.Release of mycobacterial antigens.C. pseudotuberculosis Phop confers virulence and may be targeted by natural compounds.MTBVAC from discovery to clinical trials in tuberculosis-endemic countries.EspR-dependent ESAT-6 Protein Secretion of Mycobacterium tuberculosis Requires the Presence of Virulence Regulator PhoP.Mycobacterium tuberculosis PhoP recognizes two adjacent direct-repeat sequences to form head-to-head dimers.Unique N-terminal arm of Mycobacterium tuberculosis PhoP protein plays an unusual role in its regulatory function.
P2860
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P2860
A point mutation in the two-component regulator PhoP-PhoR accounts for the absence of polyketide-derived acyltrehaloses but not that of phthiocerol dimycocerosates in Mycobacterium tuberculosis H37Ra.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
A point mutation in the two-co ...... obacterium tuberculosis H37Ra.
@ast
A point mutation in the two-co ...... obacterium tuberculosis H37Ra.
@en
type
label
A point mutation in the two-co ...... obacterium tuberculosis H37Ra.
@ast
A point mutation in the two-co ...... obacterium tuberculosis H37Ra.
@en
prefLabel
A point mutation in the two-co ...... obacterium tuberculosis H37Ra.
@ast
A point mutation in the two-co ...... obacterium tuberculosis H37Ra.
@en
P2093
P2860
P50
P356
P1476
A point mutation in the two-co ...... obacterium tuberculosis H37Ra.
@en
P2093
Frédéric Boudou
Jesús Gonzalo Asensio
Marie-Laure Chesne-Seck
Pappachan E Kolattukudy
Stewart T Cole
P2860
P304
P356
10.1128/JB.01465-07
P407
P577
2007-12-07T00:00:00Z