about
Synthesis and biochemical evaluation of selective inhibitors of class II fructose bisphosphate aldolases: towards new synthetic antibioticsConformational changes upon ligand binding in the essential class II fumarase Rv1098c from Mycobacterium tuberculosisA dual conformation of the post-decarboxylation intermediate is associated with distinct enzyme states in mycobacterial KGD (α-ketoglutarate decarboxylase)Secondary structure reshuffling modulates glycosyltransferase function at the membraneThe crystal structure of the catalytic domain of the ser/thr kinase PknA from M. tuberculosis shows an Src-like autoinhibited conformationMolecular Basis of the Activity and the Regulation of the Eukaryotic-like S/T Protein Kinase PknG from Mycobacterium tuberculosisp-Hydroxybenzoic acid synthesis in Mycobacterium tuberculosisThe virulence-associated two-component PhoP-PhoR system controls the biosynthesis of polyketide-derived lipids in Mycobacterium tuberculosisCapsular glucan and intracellular glycogen of Mycobacterium tuberculosis: biosynthesis and impact on the persistence in miceGenetic basis for the biosynthesis of methylglucose lipopolysaccharides in Mycobacterium tuberculosisBiosynthetic origin of the galactosamine substituent of Arabinogalactan in Mycobacterium tuberculosisThe Ser/Thr protein kinase PknB is essential for sustaining mycobacterial growthComparative investigation of the pathogenicity of three Mycobacterium tuberculosis mutants defective in the synthesis of p-hydroxybenzoic acid derivativesThiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrGIsoxyl activation is required for bacteriostatic activity against Mycobacterium tuberculosisA point mutation in the two-component regulator PhoP-PhoR accounts for the absence of polyketide-derived acyltrehaloses but not that of phthiocerol dimycocerosates in Mycobacterium tuberculosis H37Ra.AftD, a novel essential arabinofuranosyltransferase from mycobacteria.The crystal structure of PknI from Mycobacterium tuberculosis shows an inactive, pseudokinase-like conformation.GarA is an essential regulator of metabolism in Mycobacterium tuberculosis.Structure-based Virtual Screening to Get New Scaffold Inhibitors of the Ser/Thr Protein Kinase PknB from Mycobacterium tuberculosis
P50
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P50
name
Nathalie Barilone
@ast
Nathalie Barilone
@en
Nathalie Barilone
@nl
type
label
Nathalie Barilone
@ast
Nathalie Barilone
@en
Nathalie Barilone
@nl
prefLabel
Nathalie Barilone
@ast
Nathalie Barilone
@en
Nathalie Barilone
@nl