A dominant negative retinoic acid receptor blocks neutrophil differentiation at the promyelocyte stage.
about
FAM20: an evolutionarily conserved family of secreted proteins expressed in hematopoietic cellsRAC3, a steroid/nuclear receptor-associated coactivator that is related to SRC-1 and TIF2PML, a growth suppressor disrupted in acute promyelocytic leukemiaGrowth factor independence-1 (Gfi-1) plays a role in mediating specific granule deficiency (SGD) in a patient lacking a gene-inactivating mutation in the C/EBPepsilon geneGranulocyte heterochromatin: defining the epigenome.Positive evidence for vitamin A role in prevention of type 1 diabetesA murine antibacterial ortholog to human bactericidal/permeability-increasing protein (BPI) is expressed in testis, epididymis, and bone marrowRetinoic acid and arsenic synergize to eradicate leukemic cells in a mouse model of acute promyelocytic leukemiaMinireview: Nuclear receptors, hematopoiesis, and stem cells.C/EBPepsilon directs granulocytic-vs-monocytic lineage determination and confers chemotactic function via Hlx.CCAAT/enhancer binding protein alpha is a regulatory switch sufficient for induction of granulocytic development from bipotential myeloid progenitorsTargeted disruption of the MYC antagonist MAD1 inhibits cell cycle exit during granulocyte differentiation.Transcription therapy for acute promyelocytic leukaemia.Retinoic acid receptor alpha (RAralpha) Mutations in Human Leukemia.MAD1 and p27(KIP1) cooperate to promote terminal differentiation of granulocytes and to inhibit Myc expression and cyclin E-CDK2 activityASB2 is an Elongin BC-interacting protein that can assemble with Cullin 5 and Rbx1 to reconstitute an E3 ubiquitin ligase complex.Function of RARalpha during the maturation of neutrophils.Transcriptional regulation in acute promyelocytic leukemia.c-MYC coordinately regulates ribosomal gene chromatin remodeling and Pol I availability during granulocyte differentiationActive repression by unliganded retinoid receptors in development: less is sometimes moreRara haploinsufficiency modestly influences the phenotype of acute promyelocytic leukemia in mice.Diminished potential for B-lymphoid differentiation after murine leukemia virus infection in vivo and in EML hematopoietic progenitor cells.Differentiation and characterization of myeloid cells.Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies.Physical interaction between retinoic acid receptor and the oncoprotein myb inhibits retinoic acid-dependent transactivationRepresentational difference analysis of a committed myeloid progenitor cell line reveals evidence for bilineage potential.Dissecting the role of retinoic acid receptor isoforms in the CD8 response to infection.A CXCL1 paracrine network links cancer chemoresistance and metastasisNeutrophil-selective CD18 silencing using RNA interference in vivoA retinoic acid response element that overlaps an estrogen response element mediates multihormonal sensitivity in transcriptional activation of the lactoferrin gene.Plasma glutamate-modulated interaction of A2AR and mGluR5 on BMDCs aggravates traumatic brain injury-induced acute lung injuryGranulocytic nuclear differentiation of lamin B receptor-deficient mouse EPRO cells.Agents under investigation for the treatment and prevention of neutropenia.A novel method for long term bone marrow culture and genetic modification of murine neutrophils via retroviral transduction.Transgenic expression of PML/RARalpha impairs myelopoiesis.Antagonizing Retinoic Acid Receptors Increases Myeloid Cell Production by Cultured Human Hematopoietic Stem Cells.The antiproliferative ELF2 isoform, ELF2B, induces apoptosis in vitro and perturbs early lymphocytic development in vivoDifferentiation therapy of acute myeloid leukemia.p120 nucleolar-proliferating antigen is a direct target of G-CSF signaling during myeloid differentiation.AML1/ETO accelerates cell migration and impairs cell-to-cell adhesion and homing of hematopoietic stem/progenitor cells.
P2860
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P2860
A dominant negative retinoic acid receptor blocks neutrophil differentiation at the promyelocyte stage.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
A dominant negative retinoic a ...... ion at the promyelocyte stage.
@ast
A dominant negative retinoic a ...... ion at the promyelocyte stage.
@en
type
label
A dominant negative retinoic a ...... ion at the promyelocyte stage.
@ast
A dominant negative retinoic a ...... ion at the promyelocyte stage.
@en
prefLabel
A dominant negative retinoic a ...... ion at the promyelocyte stage.
@ast
A dominant negative retinoic a ...... ion at the promyelocyte stage.
@en
P2860
P356
P1476
A dominant negative retinoic a ...... ion at the promyelocyte stage.
@en
P2093
P2860
P304
P356
10.1073/PNAS.90.15.7153
P407
P577
1993-08-01T00:00:00Z