Conformational changes of the glucocorticoid receptor ligand binding domain induced by ligand and cofactor binding, and the location of cofactor binding sites determined by hydrogen/deuterium exchange mass spectrometry
about
Hormone binding and co-regulator binding to the glucocorticoid receptor are allosterically coupled.Insights on glucocorticoid receptor activity modulation through the binding of rigid steroids.Conformational dynamics of human FXR-LBD ligand interactions studied by hydrogen/deuterium exchange mass spectrometry: insights into the antagonism of the hypolipidemic agent Z-guggulsterone.In silico discovery of androgen receptor antagonists with activity in castration resistant prostate cancerAnalysis of agonist and antagonist effects on thyroid hormone receptor conformation by hydrogen/deuterium exchange.Antiinflammatory glucocorticoid receptor ligand with reduced side effects exhibits an altered protein-protein interaction profile.What goes on behind closed doors: physiological versus pharmacological steroid hormone actions.Differential hydrogen/deuterium exchange mass spectrometry analysis of protein-ligand interactionsSmall molecule modulation of nuclear receptor conformational dynamics: implications for function and drug discoveryDifferential modulation of glucocorticoid and progesterone receptor transactivation.The glucocorticoid receptor dimer interface allosterically transmits sequence-specific DNA signals.Probing Dominant Negative Behavior of Glucocorticoid Receptor β through a Hybrid Structural and Biochemical Approach.An Approach to Greater Specificity for Glucocorticoids.A screening assay for Selective Dimerizing Glucocorticoid Receptor Agonists and Modulators (SEDIGRAM) that are effective against acute inflammation
P2860
Q33545556-208873BA-0959-44EB-AD25-4DB15D5B2E06Q33719222-2F3A8957-2AF2-44AE-BACC-A4BE027C0531Q34065876-E940D38E-821F-4295-9304-AF560A286448Q34424735-6DFEB3AA-307E-45DD-9FC7-F17C530CC9ACQ34548893-61082A7A-0907-4C54-96F6-BAF88FD526DAQ34717142-D04EFCA1-1993-4C70-A83A-AFCB04E71444Q34795516-693B29B8-6635-4D3F-93CC-FD384C35D91CQ35040616-4276B8F9-6068-4BDE-84A5-D9F795CFA098Q36497819-C566BC3D-45FF-44CA-8D7B-2B1FDF60C9C5Q36510988-DB534FEA-9875-4BAF-B667-286C8DFAA8D6Q36986235-349EDA92-FF16-4E4F-A8E0-F792E140D327Q50043678-FD46512D-C77F-4567-B867-654BE0E8E3E6Q52624565-F9F771EB-3B79-4A71-BF8B-054C41416686Q57203553-4C69FF62-8D01-4634-8E73-0AA42827ADA3
P2860
Conformational changes of the glucocorticoid receptor ligand binding domain induced by ligand and cofactor binding, and the location of cofactor binding sites determined by hydrogen/deuterium exchange mass spectrometry
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Conformational changes of the ...... ium exchange mass spectrometry
@ast
Conformational changes of the ...... ium exchange mass spectrometry
@en
type
label
Conformational changes of the ...... ium exchange mass spectrometry
@ast
Conformational changes of the ...... ium exchange mass spectrometry
@en
prefLabel
Conformational changes of the ...... ium exchange mass spectrometry
@ast
Conformational changes of the ...... ium exchange mass spectrometry
@en
P2860
P356
P1433
P1476
Conformational changes of the ...... ium exchange mass spectrometry
@en
P2093
Walter Davidson
P2860
P304
P356
10.1110/PS.051781406
P577
2006-04-01T00:00:00Z