Conformational changes of the glucocorticoid receptor ligand binding domain induced by ligand and cofactor binding, and the location of cofactor binding sites determined by hydrogen/deuterium exchange mass spectrometry

Conformational changes of the glucocorticoid receptor ligand binding domain induced by ligand and cofactor binding, and the location of cofactor binding sites determined by hydrogen/deuterium exchange mass spectrometry

Item
http://www.wikidata.org/entity/Q36458264
Hormone binding and co-regulator binding to the glucocorticoid receptor are allosterically coupled.Insights on glucocorticoid receptor activity modulation through the binding of rigid steroids.Conformational dynamics of human FXR-LBD ligand interactions studied by hydrogen/deuterium exchange mass spectrometry: insights into the antagonism of the hypolipidemic agent Z-guggulsterone.In silico discovery of androgen receptor antagonists with activity in castration resistant prostate cancerAnalysis of agonist and antagonist effects on thyroid hormone receptor conformation by hydrogen/deuterium exchange.Antiinflammatory glucocorticoid receptor ligand with reduced side effects exhibits an altered protein-protein interaction profile.What goes on behind closed doors: physiological versus pharmacological steroid hormone actions.Differential hydrogen/deuterium exchange mass spectrometry analysis of protein-ligand interactionsSmall molecule modulation of nuclear receptor conformational dynamics: implications for function and drug discoveryDifferential modulation of glucocorticoid and progesterone receptor transactivation.The glucocorticoid receptor dimer interface allosterically transmits sequence-specific DNA signals.Probing Dominant Negative Behavior of Glucocorticoid Receptor β through a Hybrid Structural and Biochemical Approach.An Approach to Greater Specificity for Glucocorticoids.A screening assay for Selective Dimerizing Glucocorticoid Receptor Agonists and Modulators (SEDIGRAM) that are effective against acute inflammation
P2860

Conformational changes of the glucocorticoid receptor ligand binding domain induced by ligand and cofactor binding, and the location of cofactor binding sites determined by hydrogen/deuterium exchange mass spectrometry

Item
http://www.wikidata.org/entity/Q36458264
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Conformational changes of the ...... ium exchange mass spectrometry
@ast
Conformational changes of the ...... ium exchange mass spectrometry
@en
type
label
Conformational changes of the ...... ium exchange mass spectrometry
@ast
Conformational changes of the ...... ium exchange mass spectrometry
@en
prefLabel
Conformational changes of the ...... ium exchange mass spectrometry
@ast
Conformational changes of the ...... ium exchange mass spectrometry
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P921
P932
P356
P1433
P1476
Conformational changes of the ...... ium exchange mass spectrometry
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P921
P932