Defective signal transduction in B lymphocytes lacking presenilin proteins. - Wikidata - wikimedia - TriplyDB

Defective signal transduction in B lymphocytes lacking presenilin proteins.

Defective signal transduction in B lymphocytes lacking presenilin proteins.

http://www.wikidata.org/entity/Q36458887

about

Alzheimer's disease phenotypes and genotypes associated with mutations in presenilin 2.Presenilin 2 is the predominant γ-secretase in microglia and modulates cytokine release Presenilin/gamma-Secretase and Inflammation.Presenilin 2 influences miR146 level and activity in microglia.γ-Secretase directly sheds the survival receptor BCMA from plasma cells Familial Alzheimer's disease mutations in presenilins: effects on endoplasmic reticulum calcium homeostasis and correlation with clinical phenotypes.Genetics of Alzheimer's disease: an insight into presenilins and apolipoprotein E instigated neurodegeneration.Interleukin-1 receptor type 1 is a substrate for gamma-secretase-dependent regulated intramembrane proteolysis.Presenilin-2 dampens intracellular Ca2+ stores by increasing Ca2+ leakage and reducing Ca2+ uptake Genetic rescue of lineage-balanced blood cell production reveals a crucial role for STAT3 antiinflammatory activity in hematopoiesis.Regulated intramembrane proteolysis: emergent role in cell signalling pathways.Loss of Presenilin 2 Function Is Associated with Defective LPS-Mediated Innate Immune Responsiveness.

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Defective signal transduction in B lymphocytes lacking presenilin proteins.

http://www.wikidata.org/entity/Q36458887

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

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2008年學術文章

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name

Defective signal transduction in B lymphocytes lacking presenilin proteins.

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Defective signal transduction in B lymphocytes lacking presenilin proteins.

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type

label

Defective signal transduction in B lymphocytes lacking presenilin proteins.

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Defective signal transduction in B lymphocytes lacking presenilin proteins.

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Defective signal transduction in B lymphocytes lacking presenilin proteins.

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Defective signal transduction in B lymphocytes lacking presenilin proteins.

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Proceedings of the National Academy of Sciences of the United States of America

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Defective signal transduction in B lymphocytes lacking presenilin proteins.

@en

P2093

Albert C Shaw

http://www.w3.org/2001/XMLSchema#string

Christina Scheidig

http://www.w3.org/2001/XMLSchema#string

Cosmas Giallourakis

http://www.w3.org/2001/XMLSchema#string

Hui Zheng

http://www.w3.org/2001/XMLSchema#string

Jie Shen

http://www.w3.org/2001/XMLSchema#string

Ramnik J Xavier

http://www.w3.org/2001/XMLSchema#string

Subhasis Mohanty

http://www.w3.org/2001/XMLSchema#string

Tomohito Yagi

http://www.w3.org/2001/XMLSchema#string

P2860

Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations

Identification of a gene causing human cytochrome c oxidase deficiency by integrative genomics.

A gene atlas of the mouse and human protein-encoding transcriptomes

Identifying biological themes within lists of genes with EASE

DAVID: Database for Annotation, Visualization, and Integrated Discovery

Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease

Deficient neurogenesis in forebrain-specific presenilin-1 knockout mice is associated with reduced clearance of hippocampal memory traces

Skeletal and CNS defects in Presenilin-1-deficient mice

Mice lacking both presenilin genes exhibit early embryonic patterning defects

Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm

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18195359

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2242696

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