SNCA variants are associated with increased risk for multiple system atrophy. - Wikidata - wikimedia - TriplyDB

SNCA variants are associated with increased risk for multiple system atrophy.

SNCA variants are associated with increased risk for multiple system atrophy.

http://www.wikidata.org/entity/Q36460907

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Genetic variants of the alpha-synuclein gene SNCA are associated with multiple system atrophy Copy number loss of (src homology 2 domain containing)-transforming protein 2 (SHC2) gene: discordant loss in monozygotic twins and frequent loss in patients with multiple system atrophy Genome-wide association study reveals genetic risk underlying Parkinson's disease Neuropathology of non-Alzheimer degenerative disorders Review: Multiple system atrophy: emerging targets for interventional therapies Genetics Underlying Atypical Parkinsonism and Related Neurodegenerative Disorders Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism Glia and alpha-synuclein in neurodegeneration: A complex interaction The genetics and neuropathology of Parkinson's disease Alpha-synuclein biology in Lewy body diseases Animal modeling an oligodendrogliopathy--multiple system atrophy Selective binding of nuclear alpha-synuclein to the PGC1alpha promoter under conditions of oxidative stress may contribute to losses in mitochondrial function: implications for Parkinson's disease Genomic risk profiling of ischemic stroke: results of an international genome-wide association meta-analysis Systemic proteasome inhibition triggers neurodegeneration in a transgenic mouse model expressing human α-synuclein under oligodendrocyte promoter: implications for multiple system atrophy.Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson's disease models Lipid classes and fatty acid patterns are altered in the brain of γ-synuclein null mutant mice.Towards translational therapies for multiple system atrophy Mesenchymal stem cells in a transgenic mouse model of multiple system atrophy: immunomodulation and neuroprotection Targeted overexpression of human alpha-synuclein in oligodendroglia induces lesions linked to MSA-like progressive autonomic failure.The genetic contributions of SNCA and LRRK2 genes to Lewy Body pathology in Alzheimer's disease.Multiple system atrophy as emerging template for accelerated drug discovery in α-synucleinopathies LINGO1 and LINGO2 variants are associated with essential tremor and Parkinson disease The neuropathology, pathophysiology and genetics of multiple system atrophy.SHC2 gene copy number in multiple system atrophy (MSA)Evaluation of the role of SNCA variants in survival without neurological disease Increased neuronal α-synuclein pathology associates with its accumulation in oligodendrocytes in mice modeling α-synucleinopathies Analysis of COQ2 gene in multiple system atrophy.The effect of SNCA 3' region on the levels of SNCA-112 splicing variant.LRRK2 exonic variants and risk of multiple system atrophy.Independent and joint effects of the MAPT and SNCA genes in Parkinson disease.The neurogenetics of atypical parkinsonian disorders Multiple system atrophy is not caused by C9orf72 hexanucleotide repeat expansions.Analysis of C9orf72 repeat expansions in a large series of clinically and pathologically diagnosed cases with atypical parkinsonism.Functional alterations to the nigrostriatal system in mice lacking all three members of the synuclein family.Toll-like receptor 4 promotes α-synuclein clearance and survival of nigral dopaminergic neurons.Genetic players in multiple system atrophy: unfolding the nature of the beast.Variants associated with Gaucher disease in multiple system atrophy.Pregnancy in multiple system atrophy: a case report Genetic Variants of SNCA Are Associated with Susceptibility to Parkinson's Disease but Not Amyotrophic Lateral Sclerosis or Multiple System Atrophy in a Chinese Population.Plasma Homocysteine, Vitamin B12 and Folate Levels in Multiple System Atrophy: A Case-Control Study.

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SNCA variants are associated with increased risk for multiple system atrophy.

http://www.wikidata.org/entity/Q36460907

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2009 nî lūn-bûn

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2009年の論文

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2009年學術文章

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2009年學術文章

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SNCA variants are associated with increased risk for multiple system atrophy.

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SNCA variants are associated with increased risk for multiple system atrophy.

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SNCA variants are associated with increased risk for multiple system atrophy.

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SNCA variants are associated with increased risk for multiple system atrophy.

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SNCA variants are associated with increased risk for multiple system atrophy.

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SNCA variants are associated with increased risk for multiple system atrophy.

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Annals of Neurology

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SNCA variants are associated with increased risk for multiple system atrophy.

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P2093

Abi Li

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Anna Melchers

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Bryan J Traynor

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Francesca Del Sorbo

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Henry Houlden

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J Raphael Gibbs

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Janice Holton

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Javier Simon-Sanchez

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Jinhui Ding

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Manu Sharma

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PLINK: a tool set for whole-genome association and population-based linkage analyses

alpha-Synuclein locus triplication causes Parkinson's disease

Multiple system atrophy/progressive supranuclear palsy: alpha-Synuclein, synphilin, tau, and APOE.

Synucleinopathies: clinical and pathological implications.

Probable multiple system atrophy in a German family

The law of mass action applied to neurodegenerative disease: a hypothesis concerning the etiology and pathogenesis of complex diseases.

The alpha-synuclein gene in multiple system atrophy

Quantitative PCR-based screening of alpha-synuclein multiplication in multiple system atrophy

Environmental-occupational risk factors and familial associations in multiple system atrophy: a preliminary investigation.

Transcriptional changes in multiple system atrophy and Parkinson's disease putamen.

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610-614

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10.1002/ANA.21685

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5

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65

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Wolfgang H. Oertel

Claudia Schulte

Michael S. Okun

Kailash Phatechand Bhatia

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2009-05-01T00:00:00Z

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26246968

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19475667

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3520128

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