Elovl5 regulates the mTORC2-Akt-FOXO1 pathway by controlling hepatic cis-vaccenic acid synthesis in diet-induced obese mice
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Is Western Diet-Induced Nonalcoholic Steatohepatitis in Ldlr-/- Mice Reversible?The Mechanistic Target of Rapamycin: The Grand ConducTOR of Metabolism and AgingDocosahexaenoic acid blocks progression of western diet-induced nonalcoholic steatohepatitis in obese Ldlr-/- mice.Fatty acid elongase-5 (Elovl5) regulates hepatic triglyceride catabolism in obese C57BL/6J miceA high-fat diet suppresses de novo lipogenesis and desaturation but not elongation and triglyceride synthesis in mice.Deletion of ELOVL6 blocks the synthesis of oleic acid but does not prevent the development of fatty liver or insulin resistance.Prospective association of fatty acids in the de novo lipogenesis pathway with risk of type 2 diabetes: the Cardiovascular Health Study.Impact of dietary fat on the development of non-alcoholic fatty liver disease in Ldlr-/- mice.Comparative mRNA Expression of eEF1A Isoforms and a PI3K/Akt/mTOR Pathway in a Cellular Model of Parkinson's DiseaseCis-vaccenic acid induces differentiation and up-regulates gamma globin synthesis in K562, JK1 and transgenic mice erythroid progenitor stem cells.Fatty acid-regulated transcription factors in the liver.Metabolic control of signalling pathways and metabolic auto-regulation.Inactivation of fatty acid synthase impairs hepatocarcinogenesis driven by AKT in mice and humans.The IGF2 mRNA binding protein p62/IGF2BP2-2 induces fatty acid elongation as a critical feature of steatosis.Perilipin-2 Deletion Impairs Hepatic Lipid Accumulation by Interfering with Sterol Regulatory Element-binding Protein (SREBP) Activation and Altering the Hepatic Lipidome.SREBP-regulated lipid metabolism: convergent physiology - divergent pathophysiology.Stress-activated miR-21/miR-21* in hepatocytes promotes lipid and glucose metabolic disorders associated with high-fat diet consumption.Lipid profile changes in erythrocyte membranes of women with diagnosed GDM
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Elovl5 regulates the mTORC2-Akt-FOXO1 pathway by controlling hepatic cis-vaccenic acid synthesis in diet-induced obese mice
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2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年學術文章
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2012年學術文章
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2012年學術文章
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name
Elovl5 regulates the mTORC2-Ak ...... sis in diet-induced obese mice
@ast
Elovl5 regulates the mTORC2-Ak ...... sis in diet-induced obese mice
@en
type
label
Elovl5 regulates the mTORC2-Ak ...... sis in diet-induced obese mice
@ast
Elovl5 regulates the mTORC2-Ak ...... sis in diet-induced obese mice
@en
prefLabel
Elovl5 regulates the mTORC2-Ak ...... sis in diet-induced obese mice
@ast
Elovl5 regulates the mTORC2-Ak ...... sis in diet-induced obese mice
@en
P2860
P356
P1476
Elovl5 regulates the mTORC2-Ak ...... sis in diet-induced obese mice
@en
P2093
Donald B Jump
Sasmita Tripathy
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P356
10.1194/JLR.M028787
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2012-10-24T00:00:00Z