A Missense Mutation in PPP1R15B Causes a Syndrome Including Diabetes, Short Stature, and Microcephaly
about
An inhibitor of HIV-1 protease modulates constitutive eIF2α dephosphorylation to trigger a specific integrated stress response.Protein kinase R(PKR)-like endoplasmic reticulum kinase (PERK) inhibitors: a patent review (2010-2015).Endoplasmic reticulum stress and eIF2α phosphorylation: The Achilles heel of pancreatic β cells.EIF2S3 Mutations Associated with Severe X-Linked Intellectual Disability Syndrome MEHMO.PPP1R15A-mediated dephosphorylation of eIF2α is unaffected by Sephin1 or Guanabenz.Complementary Roles of GADD34- and CReP-Containing Eukaryotic Initiation Factor 2α Phosphatases during the Unfolded Protein Response.Checks and Balances-The Limits of β-Cell Endurance to ER Stress.Pancreatic β-cell protection from inflammatory stress by the endoplasmic reticulum proteins thrombospondin 1 and mesencephalic astrocyte-derived neutrotrophic factor (MANF).Two novel EIF2S3 mutations associated with syndromic intellectual disability with severe microcephaly, growth retardation, and epilepsy.Target-Based Discovery of an Inhibitor of the Regulatory Phosphatase PPP1R15B
P2860
Q36483172-E581516A-7239-4008-A66B-9619D81096F7Q38819666-FFF849F1-7AA2-48AB-B0DE-A32D6A500222Q41689677-B577BF76-B864-4D14-8EAA-8EEDD58B7A34Q41921225-120DAFE7-075B-46FA-B438-0FD8929B5324Q42058506-55FC1258-A2F6-4349-BE00-D27EBFFDF91DQ42156227-9A69F1E8-C2AE-4E86-B8EC-1E2F14E768A4Q48114308-0EB732BB-90BC-4F23-ABAE-635FDC6797D0Q48724578-F17AE669-CEEC-448D-A8E6-2B204BD7A3D5Q52130242-CF917D81-1224-4340-84AF-3BEABDB5337DQ58713486-65566133-AD6D-443B-9A4C-831F8BAFCC6A
P2860
A Missense Mutation in PPP1R15B Causes a Syndrome Including Diabetes, Short Stature, and Microcephaly
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年學術文章
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name
A Missense Mutation in PPP1R15 ...... hort Stature, and Microcephaly
@ast
A Missense Mutation in PPP1R15 ...... hort Stature, and Microcephaly
@en
type
label
A Missense Mutation in PPP1R15 ...... hort Stature, and Microcephaly
@ast
A Missense Mutation in PPP1R15 ...... hort Stature, and Microcephaly
@en
prefLabel
A Missense Mutation in PPP1R15 ...... hort Stature, and Microcephaly
@ast
A Missense Mutation in PPP1R15 ...... hort Stature, and Microcephaly
@en
P2093
P2860
P50
P356
P1433
P1476
A Missense Mutation in PPP1R15 ...... hort Stature, and Microcephaly
@en
P2093
Céline Derbois
Daniel A Cunha
Décio L Eizirik
Marc Nicolino
Mariana Igoillo-Esteve
Mathilde Daures
Miguel Lopes
Nathalie Bendelac
Sophie Romero
P2860
P304
P356
10.2337/DB15-0477
P407
P50
P577
2015-07-09T00:00:00Z