A recombinant immunotoxin containing a disulfide-stabilized Fv fragment.
about
Making artificial antibodies: a format for phage display of combinatorial heterodimeric arraysThe production of antibody fragments and antibody fusion proteins by yeasts and filamentous fungiEngineered hapten-binding antibody derivatives for modulation of pharmacokinetic properties of small molecules and targeted payload deliveryNovel immunotherapies in lymphoid malignanciesListeriolysin O as cytotoxic component of an immunotoxinIn vitro antibody evolution targeting germline hot spots to increase activity of an anti-CD22 immunotoxin.Production of unique immunotoxin cancer therapeutics in algal chloroplastsA small bispecific antibody construct expressed as a functional single-chain molecule with high tumor cell cytotoxicity.Delivery and therapeutic potential of human granzyme B.Recombinant immunotoxins for cancer therapy.Intrathecal administration of single-chain immunotoxin, LMB-7 [B3(Fv)-PE38], produces cures of carcinomatous meningitis in a rat modelSV40 Pseudovirion gene delivery of a toxin to treat human adenocarcinomas in mice.Strategies to stabilize compact folding and minimize aggregation of antibody-based fragmentsA guide to taming a toxin--recombinant immunotoxins constructed from Pseudomonas exotoxin A for the treatment of cancer.Disulfide-stabilized single-chain antibody-targeted superantigen: construction of a prokaryotic expression system and its functional analysis.Antibody fusion proteins: anti-CD22 recombinant immunotoxin moxetumomab pasudotoxRapid humanization of the Fv of monoclonal antibody B3 by using framework exchange of the recombinant immunotoxin B3(Fv)-PE38.Fab-based bispecific antibody formats with robust biophysical properties and biological activityRemodeling domain interfaces to enhance heterodimer formationExpression cloning of cDNAs that render cancer cells resistant to Pseudomonas and diphtheria toxin and immunotoxins.Fungal ribotoxins: molecular dissection of a family of natural killers.The affinity-selection of a minibody polypeptide inhibitor of human interleukin-6.A combinatorial library strategy for the rapid humanization of anticarcinoma BR96 Fab.Comparison of strategies for the construction of libraries of artificial antibodies.Immunotoxins: the role of the toxin.Construction of a disulfide-stabilized diabody against fibroblast growth factor-2 and the inhibition activity in targeting breast cancer.Fab-dsFv: A bispecific antibody format with extended serum half-life through albumin binding.Improved antitumor activity of a recombinant anti-Lewis(y) immunotoxin not requiring proteolytic activation.Inhibition activity of a disulfide-stabilized diabody against basic fibroblast growth factor in lung cancer.Metabolic engineering of recombinant protein secretion by Saccharomyces cerevisiae.Potential applications of designed ankyrin repeat proteins in diagnostics and therapeutics.Identification of residues that stabilize the single-chain Fv of monoclonal antibodies B3.The future of antiviral immunotoxins.Fluorescent Citrine-IgG fusion proteins produced in mammalian cells.Killing of target cells by redirected granzyme B in the absence of perforin.Targeting of T lymphocytes to melanoma cells through chimeric anti-GD3 immunoglobulin T-cell receptors.Conjugation of an antibody Fv fragment to a virus coat protein: cell-specific targeting of recombinant polyoma-virus-like particlesDesign, characterization and anti-tumour cytotoxicity of a panel of recombinant, mammalian ribonuclease-based immunotoxins.The making of bispecific antibodiesBioinformatics in molecular immunology laboratories demonstrated: Modeling an anti-CMV scFv antibody.
P2860
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P2860
A recombinant immunotoxin containing a disulfide-stabilized Fv fragment.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
A recombinant immunotoxin containing a disulfide-stabilized Fv fragment.
@ast
A recombinant immunotoxin containing a disulfide-stabilized Fv fragment.
@en
type
label
A recombinant immunotoxin containing a disulfide-stabilized Fv fragment.
@ast
A recombinant immunotoxin containing a disulfide-stabilized Fv fragment.
@en
prefLabel
A recombinant immunotoxin containing a disulfide-stabilized Fv fragment.
@ast
A recombinant immunotoxin containing a disulfide-stabilized Fv fragment.
@en
P2093
P2860
P356
P1476
A recombinant immunotoxin containing a disulfide-stabilized Fv fragment.
@en
P2093
P2860
P304
P356
10.1073/PNAS.90.16.7538
P407
P577
1993-08-01T00:00:00Z