Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent - Wikidata - wikimedia - TriplyDB

Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent

Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent

http://www.wikidata.org/entity/Q36483421

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IQGAP1 and IQGAP2 are reciprocally altered in hepatocellular carcinoma IQGAPs in cancer: a family of scaffold proteins underlying tumorigenesis Crystal structure of the GTPase-activating protein-related domain from IQGAP1 The biology of IQGAP proteins: beyond the cytoskeleton Targeting Cdc42 in cancer IQGAP1 functions as a modulator of dishevelled nuclear localization in Wnt signaling IQGAP3 regulates cell proliferation through the Ras/ERK signalling cascade IQGAP3 is essential for cell proliferation and motility during zebrafish embryonic development.Integration of DNA copy number alterations and transcriptional expression analysis in human gastric cancer.Class prediction models of thrombocytosis using genetic biomarkers.Identification of cellular targets in human intrahepatic cholangiocarcinoma using laser microdissection and accurate mass and time tag proteomics Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model Role of the tumor suppressor IQGAP2 in metabolic homeostasis: Possible link between diabetes and cancer.Network features suggest new hepatocellular carcinoma treatment strategies Transcript profiling identifies iqgap2(-/-) mouse as a model for advanced human hepatocellular carcinoma.Efficacy of mesenchymal stem cells in suppression of hepatocarcinorigenesis in rats: possible role of Wnt signaling.Dynamic expression patterns of differential proteins during early invasion of hepatocellular carcinoma.IQGAPs choreograph cellular signaling from the membrane to the nucleus IQGAP3 promotes EGFR-ERK signaling and the growth and metastasis of lung cancer cells.Ablation of Iqgap2 protects from diet-induced hepatic steatosis due to impaired fatty acid uptake IQ Motif-Containing GTPase-Activating Protein 2 (IQGAP2) Is a Novel Regulator of Colonic Inflammation in Mice.Sulfatase 1 and sulfatase 2 in hepatocellular carcinoma: associated signaling pathways, tumor phenotypes, and survival.The Overexpression of IQGAP1 and β-Catenin Is Associated with Tumor Progression in Hepatocellular Carcinoma In Vitro and In Vivo.Watch the GAP: Emerging Roles for IQ Motif-Containing GTPase-Activating Proteins IQGAPs in Hepatocellular Carcinoma Integrated genomic profiling identifies microRNA-92a regulation of IQGAP2 in locally advanced rectal cancer Research resource: identification of novel coregulators specific for thyroid hormone receptor-β2.Protein scaffolds in MAP kinase signalling.Structure and function of IQ-domain GTPase-activating protein 1 and its association with tumor progression (Review).Bile acids activate YAP to promote liver carcinogenesis.IQGAP1 is a phosphoinositide effector and kinase scaffold IQGAP1‑siRNA inhibits proliferation and metastasis of U251 and U373 glioma cell lines Absence of IQGAP1 Protein Leads to Insulin Resistance.Agonist-stimulated phosphatidylinositol-3,4,5-trisphosphate generation by scaffolded phosphoinositide kinases.Altered methylation of specific DNA loci in the liver of Bhmt-null mice results in repression of Iqgap2 and F2rl2 and is associated with development of preneoplastic foci.Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcripts.IQGAP2 is a novel interferon-alpha antiviral effector gene acting non-conventionally through the NF-κB pathway.The Structural Basis for Cdc42-Induced Dimerization of IQGAPs.The cytoskeletal adaptor protein IQGAP1 regulates TCR-mediated signaling and filamentous actin dynamics.The growth pattern of transplanted normal and nodular hepatocytes.Overexpression of the Transmembrane Protein IQGAP3 Is Associated with Poor Survival of Patients with Gastric Cancer.

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Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent

http://www.wikidata.org/entity/Q36483421

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

@zh-sg

2008年學術文章

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2008年學術文章

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2008年學術文章

@zh-hant

name

Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent

@ast

Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent

@en

type

label

Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent

@ast

Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent

@en

prefLabel

Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent

@ast

Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent

@en

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P1433

Molecular and Cellular Biology

P1476

Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent

@en

P2093

Carmine S Chiariello

http://www.w3.org/2001/XMLSchema#string

Frederick Miller

http://www.w3.org/2001/XMLSchema#string

Valentina A Schmidt

http://www.w3.org/2001/XMLSchema#string

Wadie F Bahou

http://www.w3.org/2001/XMLSchema#string

P2860

The Ras GTPase-activating-protein-related human protein IQGAP2 harbors a potential actin binding domain and interacts with calmodulin and Rho family GTPases

IQGAP1, a calmodulin-binding protein with a rasGAP-related domain, is a potential effector for cdc42Hs

IQGAP2 functions as a GTP-dependent effector protein in thrombin-induced platelet cytoskeletal reorganization

IQGAP proteins are integral components of cytoskeletal regulation

Gastric hyperplasia in mice lacking the putative Cdc42 effector IQGAP1

IQGAP1, a Rac- and Cdc42-binding protein, directly binds and cross-links microfilaments

Crystal structure of a calponin homology domain

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

Sequential assembly of myosin II, an IQGAP-like protein, and filamentous actin to a ring structure involved in budding yeast cytokinesis

PAR3 is a cofactor for PAR4 activation by thrombin

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1489-1502

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scholarly article

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10.1128/MCB.01090-07

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5

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28

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Encarnación Capilla

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2008-01-07T00:00:00Z

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18180285

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2258764

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