Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivo
about
MUC1-C Oncoprotein Blocks Terminal Differentiation of Chronic Myelogenous Leukemia Cells by a ROS-Mediated MechanismRegulation of myeloid leukaemia by the cell-fate determinant MusashiAberrant Wnt Signaling in LeukemiaRole of tyrosine-kinase inhibitors in myeloproliferative neoplasms: comparative lessons learnedChronic myeloid leukemia: reminiscences and dreamsTargeting leukemia stem cells: which pathways drive self-renewal activity in T-cell acute lymphoblastic leukemia?Targeting cancer stem cells by using the nanoparticlesCancer stem cells--important players in tumor therapy resistanceMolecular mechanisms for survival regulation of chronic myeloid leukemia stem cellsHematopoietic stem cell niche maintenance during homeostasis and regenerationAdvances in understanding the leukaemia microenvironmentWnt signaling strength regulates normal hematopoiesis and its deregulation is involved in leukemia developmentSignal transduction in the chronic leukemias: implications for targeted therapiesSurvival regulation of leukemia stem cellsTelomerase inhibition targets clonogenic multiple myeloma cells through telomere length-dependent and independent mechanismsSulindac sulfide reverses aberrant self-renewal of progenitor cells induced by the AML-associated fusion proteins PML/RARα and PLZF/RARαCanonical Wnt pathway inhibitor ICG-001 induces cytotoxicity of multiple myeloma cells in Wnt-independent mannerCDK6 as a key regulator of hematopoietic and leukemic stem cell activationNOTCH1 signaling promotes human T-cell acute lymphoblastic leukemia initiating cell regeneration in supportive nichesHematopoietic stem cell: self-renewal versus differentiationVentX trans-activates p53 and p16ink4a to regulate cellular senescenceActivation of Wnt/β-catenin protein signaling induces mitochondria-mediated apoptosis in hematopoietic progenitor cellsc-Myb and its target Bmi1 are required for p190BCR/ABL leukemogenesis in mouse and human cellsSynergy between proteasome inhibitors and imatinib mesylate in chronic myeloid leukemia.Novel mechanism of tumor suppression by polarity gene discs large 1 (DLG1) revealed in a murine model of pediatric B-ALL.Loss of β-catenin triggers oxidative stress and impairs hematopoietic regeneration.Inhibition of tumorigenesis driven by different Wnt proteins requires blockade of distinct ligand-binding regions by LRP6 antibodies.β-catenin induces expression of prohibitin gene in acute leukemic cellsInhibiting glycogen synthase kinase-3 mitigates the hematopoietic acute radiation syndrome in miceDishevelled-3 phosphorylation is governed by HIPK2/PP1Cα/ITCH axis and the non-phosphorylated form promotes cancer stemness via LGR5 in hepatocellular carcinoma.Wnt4 enhances murine hematopoietic progenitor cell expansion through a planar cell polarity-like pathwayLoss of the Alox5 gene impairs leukemia stem cells and prevents chronic myeloid leukemia.Targeting Hedgehog--a cancer stem cell pathwayCBP/catenin antagonist safely eliminates drug-resistant leukemia-initiating cells.Hematopoietic stem cell function requires 12/15-lipoxygenase-dependent fatty acid metabolism.TCF1 and beta-catenin regulate T cell development and functionChronic myeloid leukemia: mechanisms of blastic transformationRegulation of the interferon regulatory factor-8 (IRF-8) tumor suppressor gene by the signal transducer and activator of transcription 5 (STAT5) transcription factor in chronic myeloid leukemiaJAK2/STAT5 inhibition by nilotinib with ruxolitinib contributes to the elimination of CML CD34+ cells in vitro and in vivo.Arachidonate 15-lipoxygenase is required for chronic myeloid leukemia stem cell survival.
P2860
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P2860
Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivo
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivo
@ast
Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivo
@en
type
label
Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivo
@ast
Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivo
@en
prefLabel
Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivo
@ast
Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivo
@en
P2093
P2860
P1433
P1476
Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivo
@en
P2093
Anand Lagoo
Hyog Young Kwon
J Michael Cook
Jordan Blum
Seung Hye Jung
P2860
P304
P356
10.1016/J.CCR.2007.11.003
P577
2007-12-01T00:00:00Z