Mycobacterium tuberculosis ESAT-6 exhibits a unique membrane-interacting activity that is not found in its ortholog from non-pathogenic Mycobacterium smegmatis. - Wikidata - wikimedia - TriplyDB

Mycobacterium tuberculosis ESAT-6 exhibits a unique membrane-interacting activity that is not found in its ortholog from non-pathogenic Mycobacterium smegmatis.

Mycobacterium tuberculosis ESAT-6 exhibits a unique membrane-interacting activity that is not found in its ortholog from non-pathogenic Mycobacterium smegmatis.

http://www.wikidata.org/entity/Q36492775

about

The ESX-5 System of Pathogenic Mycobacteria Is Involved In Capsule Integrity and Virulence through Its Substrate PPE10 Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions DNA sensor cGAS-mediated immune recognition The Disulfide Bond Cys255-Cys279 in the Immunoglobulin-Like Domain of Anthrax Toxin Receptor 2 Is Required for Membrane Insertion of Anthrax Protective Antigen Pore Mycobacterium tuberculosis ESAT-6 is a leukocidin causing Ca2+ influx, necrosis and neutrophil extracellular trap formation.A Novel ESAT-6 Secretion System-Secreted Protein EsxX of Community-Associated Staphylococcus aureus Lineage ST398 Contributes to Immune Evasion and Virulence.Identification of a two-component fatty acid kinase responsible for host fatty acid incorporation by Staphylococcus aureus Expression and purification of the functional ectodomain of human anthrax toxin receptor 2 in Escherichia coli Origami B cells with assistance of bacterial Trigger Factor Homeostasis of N-α-terminal acetylation of EsxA correlates with virulence in Mycobacterium marinum.Characterization of Mycobacterium tuberculosis EsxA membrane insertion: roles of N- and C-terminal flexible arms and central helix-turn-helix motif Autophagy-Related Proteins Target Ubiquitin-Free Mycobacterial Compartment to Promote Killing in Macrophages Characterization of differential pore-forming activities of ESAT-6 proteins from Mycobacterium tuberculosis and Mycobacterium smegmatis Mechanism of ESAT-6 membrane interaction and its roles in pathogenesis of Mycobacterium tuberculosis.EsxA membrane-permeabilizing activity plays a key role in mycobacterial cytosolic translocation and virulence: effects of single-residue mutations at glutamine 5.Disconnecting in vitro ESX-1 secretion from mycobacterial virulence.Secretion of atypical protein substrates by the ESAT-6 secretion system of Staphylococcus aureus Mycobacterium tuberculosis evolutionary pathogenesis and its putative impact on drug development.The Cell Wall Lipid PDIM Contributes to Phagosomal Escape and Host Cell Exit of Mycobacterium tuberculosis.Mycobacterium tuberculosis EsxL inhibits MHC-II expression by promoting hypermethylation in class-II transactivator loci in macrophages.Exosomes derived from tumor cells genetically modified to express Mycobacterium tuberculosis antigen: a novel vaccine for cancer therapy.Perspectives on mycobacterial vacuole-to-cytosol translocation: the importance of cytosolic access.Staphylococcal Esx proteins modulate apoptosis and release of intracellular Staphylococcus aureus during infection in epithelial cells.Mycobacterium tuberculosis EspB binds phospholipids and mediates EsxA-independent virulence.Small Molecules That Sabotage Bacterial Virulence.EspC forms a filamentous structure in the cell envelope of Mycobacterium tuberculosis and impacts ESX-1 secretion.Esx Systems and the Mycobacterial Cell Envelope: What's the Connection?cGAS-STING-TBK1-IRF3/7 induced interferon-β contributes to the clearing of non tuberculous mycobacterial infection in mice.Mycobacterial ESX-1 secretion system mediates host cell lysis through bacterium contact-dependent gross membrane disruptions.Cyclic GMP-AMP Synthase Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis.Novel Antitumor Strategy Utilizing a Plasmid Expressing a Mycobacterium tuberculosis Antigen as a "Danger Signal" to Block Immune Escape of Tumor Cells.The ins and outs of the Mycobacterium tuberculosis-containing vacuole.Two distinct conformational states of Mycobacterium tuberculosis virulent factor early secreted antigenic target 6 kDa are behind the discrepancy around its biological functions.Type VII Secretion Systems in Gram-Positive Bacteria.EspH is a hypervirulence factor for Mycobacterium marinum and essential for the secretion of the ESX-1 substrates EspE and EspF

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P2860

Mycobacterium tuberculosis ESAT-6 exhibits a unique membrane-interacting activity that is not found in its ortholog from non-pathogenic Mycobacterium smegmatis.

http://www.wikidata.org/entity/Q36492775

description

2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

@wuu

2012年学术文章

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2012年学术文章

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2012年学术文章

@zh-my

2012年学术文章

@zh-sg

2012年學術文章

@yue

2012年學術文章

@zh

2012年學術文章

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name

Mycobacterium tuberculosis ESA ...... genic Mycobacterium smegmatis.

@ast

Mycobacterium tuberculosis ESA ...... genic Mycobacterium smegmatis.

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type

label

Mycobacterium tuberculosis ESA ...... genic Mycobacterium smegmatis.

@ast

Mycobacterium tuberculosis ESA ...... genic Mycobacterium smegmatis.

@en

prefLabel

Mycobacterium tuberculosis ESA ...... genic Mycobacterium smegmatis.

@ast

Mycobacterium tuberculosis ESA ...... genic Mycobacterium smegmatis.

@en

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P356

JBC.M112.420869

P1433

Journal of Biological Chemistry

P1476

Mycobacterium tuberculosis ESA ...... ogenic Mycobacterium smegmatis

@en

P2093

Guozhong Jiang

http://www.w3.org/2001/XMLSchema#string

Jianjun Sun

http://www.w3.org/2001/XMLSchema#string

Joaquin De Leon

http://www.w3.org/2001/XMLSchema#string

Sarah Fortune

http://www.w3.org/2001/XMLSchema#string

Yue Ma

http://www.w3.org/2001/XMLSchema#string

P2860

Structure and function of the complex formed by the tuberculosis virulence factors CFP-10 and ESAT-6

The human macrophage mannose receptor directs Mycobacterium tuberculosis lipoarabinomannan-mediated phagosome biogenesis

Dissecting virulence pathways of Mycobacterium tuberculosis through protein-protein association.

Mycobacterium tuberculosis ClpP1 and ClpP2 function together in protein degradation and are required for viability in vitro and during infection

A genetic screen for Mycobacterium tuberculosis mutants defective for phagosome maturation arrest identifies components of the ESX-1 secretion system

Individual RD1-region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosis

A non-RD1 gene cluster is required for Snm secretion in Mycobacterium tuberculosis

Conclusive evidence that the major T-cell antigens of the Mycobacterium tuberculosis complex ESAT-6 and CFP-10 form a tight, 1:1 complex and characterization of the structural properties of ESAT-6, CFP-10, and the ESAT-6*CFP-10 complex. Implications

Secreted transcription factor controls Mycobacterium tuberculosis virulence

Mutually dependent secretion of proteins required for mycobacterial virulence.

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44184-44191

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scholarly article

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53

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287

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2012-11-13T00:00:00Z

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23150662

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Mycobacterium tuberculosis

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3531734

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