Cyclic GMP-AMP Synthase Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis. - Wikidata - wikimedia - TriplyDB

Cyclic GMP-AMP Synthase Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis.

Cyclic GMP-AMP Synthase Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis.

http://www.wikidata.org/entity/Q41116868

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Cytosolic Innate Immune Sensing and Signaling upon Infection Versatile myeloid cell subsets contribute to tuberculosis-associated inflammation CD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection The ESX-5 System of Pathogenic Mycobacteria Is Involved In Capsule Integrity and Virulence through Its Substrate PPE10 DNA sensor cGAS-mediated immune recognition Protection and pathology in TB: learning from the zebrafish model Glutamylation of the DNA sensor cGAS regulates its binding and synthase activity in antiviral immunity Crosstalk Between Apoptosis and Autophagy: Environmental Genotoxins, Infection, and Innate Immunity.Type I Interferon Induction by Neisseria gonorrhoeae: Dual Requirement of Cyclic GMP-AMP Synthase and Toll-like Receptor 4.Friend or Foe: Innate Sensing of HIV in the Female Reproductive Tract.The Central Role of IFI204 in IFN-β Release and Autophagy Activation during Mycobacterium bovis Infection.Getting "Inside" Type I IFNs: Type I IFNs in Intracellular Bacterial Infections DNA-sensing inflammasomes: regulation of bacterial host defense and the gut microbiota.ESX-1 exploits type I IFN-signalling to promote a regulatory macrophage phenotype refractory to IFNγ-mediated autophagy and growth restriction of intracellular mycobacteria.Inhibition of cGAS DNA Sensing by a Herpesvirus Virion Protein The Mechanism for Type I Interferon Induction by Mycobacterium tuberculosis is Bacterial Strain-Dependent.Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases SENP7 Potentiates cGAS Activation by Relieving SUMO-Mediated Inhibition of Cytosolic DNA Sensing.The E3 ubiquitin ligase RNF185 facilitates the cGAS-mediated innate immune response.Mycobacterial infection induces a specific human innate immune response.Systematic, multiparametric analysis of Mycobacterium tuberculosis intracellular infection offers insight into coordinated virulence Mycobacterium tuberculosis induces the miR-33 locus to reprogram autophagy and host lipid metabolism.ESAT-6-dependent cytosolic pattern recognition drives noncognate tuberculosis control in vivo A Role for IFITM Proteins in Restriction of Mycobacterium tuberculosis Infection.Characterization of differential pore-forming activities of ESAT-6 proteins from Mycobacterium tuberculosis and Mycobacterium smegmatis EsxA membrane-permeabilizing activity plays a key role in mycobacterial cytosolic translocation and virulence: effects of single-residue mutations at glutamine 5.Mycobacterium bovis Induces Endoplasmic Reticulum Stress Mediated-Apoptosis by Activating IRF3 in a Murine Macrophage Cell Line.Clash of the Cytokine Titans: counter-regulation of interleukin-1 and type I interferon-mediated inflammatory responses.Outrunning the Red Queen: bystander activation as a means of outpacing innate immune subversion by intracellular pathogens.AIM2 inhibits autophagy and IFN-β production during M. bovis infection Interactions between Type 1 Interferons and the Th17 Response in Tuberculosis: Lessons Learned from Autoimmune Diseases.The Emerging Roles of STING in Bacterial Infections.Autophagy and autophagy-related proteins in the immune system.Mitochondrial DNA sensing by STING signaling participates in inflammation, cancer and beyond.The role of cGAS in innate immunity and beyond.Perspectives on mycobacterial vacuole-to-cytosol translocation: the importance of cytosolic access.The Roles of Type I Interferon in Bacterial Infection.Inflammasome Activation and Function During Infection with Mycobacterium Tuberculosis.Autophagy in leukocytes and other cells: mechanisms, subsystem organization, selectivity, and links to innate immunity.Regulation and function of the cGAS-STING pathway of cytosolic DNA sensing.

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Cyclic GMP-AMP Synthase Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis.

http://www.wikidata.org/entity/Q41116868

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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2015年论文

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name

Cyclic GMP-AMP Synthase Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis.

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Cyclic GMP-AMP Synthase Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis.

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Cyclic GMP-AMP Synthase Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis.

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J.CHOM.2015.05.005

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Cell Host & Microbe

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Cyclic GMP-AMP Synthase Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis.

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Beth Levine

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Caitlyn R Scharn

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Chelsea E Stamm

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Luis H Franco

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Tuo Li

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Vidhya R Nair

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Xiao-Dong Li

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P2860

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

Extracellular M. tuberculosis DNA targets bacteria for autophagy by activating the host DNA-sensing pathway

Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation

c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response

Striking the Right Balance Determines TB or Not TB

Sensing of Mycobacterium tuberculosis and consequences to both host and bacillus

Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA

Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation

To be or not to be? How selective autophagy and cell death govern cell fate

Autophagy in infection, inflammation, and immunity

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6

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17

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Angela C Collins

Michael U Shiloh

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2015-06-02T00:00:00Z

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26048137

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Mycobacterium tuberculosis

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4499468

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