Procoagulant signalling mechanisms in lung inflammation and fibrosis: novel opportunities for pharmacological intervention?
about
Pulmonary fibrosis: patterns and perpetratorsA placebo-controlled randomized trial of warfarin in idiopathic pulmonary fibrosisMechanisms of fibrosis: therapeutic translation for fibrotic diseasePulmonary epithelium is a prominent source of proteinase-activated receptor-1-inducible CCL2 in pulmonary fibrosis.Risk of Pulmonary Embolism and Deep Venous Thrombosis in Systemic Sclerosis: A General Population-Based Study.Dabigatran, a direct thrombin inhibitor, demonstrates antifibrotic effects on lung fibroblasts.Impact of a functional polymorphism in the PAR-1 gene promoter in COPD and COPD exacerbationsA phase I study evaluating the pharmacokinetics, safety and tolerability of an antibody-based tissue factor antagonist in subjects with acute lung injury or acute respiratory distress syndrome.Comprehensive microRNA analysis in bleomycin-induced pulmonary fibrosis identifies multiple sites of molecular regulation.Coagulation and autoimmunity in scleroderma interstitial lung disease.Novel therapeutic approaches for pulmonary fibrosis.Antiinflammatory and antifibrotic effects of the oral direct thrombin inhibitor dabigatran etexilate in a murine model of interstitial lung disease.Low molecular weight heparin prevents CLP-induced acute lung injury in rats by anti-inflammatory coagulationProcoagulant, tissue factor-bearing microparticles in bronchoalveolar lavage of interstitial lung disease patients: an observational studyMicrohemorrhage is an early event in the pulmonary fibrotic disease of PECAM-1 deficient FVB/n mice.Pathophysiology of pulmonary hypertension in acute lung injury.Molecular and cellular mechanisms of pulmonary fibrosis.Pharmacologic therapies for idiopathic pulmonary fibrosis, past and future.Metalloproteinase-9 contributes to endothelial dysfunction in atherosclerosis via protease activated receptor-1.Defining the cellular repertoire of GPCRs identifies a profibrotic role for the most highly expressed receptor, protease-activated receptor 1, in cardiac fibroblasts.Stanniocalcin-1 inhibits thrombin-induced signaling and protects from bleomycin-induced lung injury.The clinical assessment of protease-activated receptor-2 expression in inflammatory cells from peripheral blood and bronchoalveolar lavage fluid in idiopathic pulmonary fibrosisPulmonary fibrosis is associated with an elevated risk of thromboembolic disease.Airway factor XIII associates with type 2 inflammation and airway obstruction in asthmatic patientsImpact of endothelial microparticles on coagulation, inflammation, and angiogenesis in age-related vascular diseasesIncreased local expression of coagulation factor X contributes to the fibrotic response in human and murine lung injury.Proteinase activated receptor 1 mediated fibrosis in a mouse model of liver injury: a role for bone marrow derived macrophages.Proteinase-activated receptor-1, CCL2, and CCL7 regulate acute neutrophilic lung inflammation.Endothelin in pulmonary fibrosis.Therapeutic modulation of coagulation and fibrinolysis in acute lung injury and the acute respiratory distress syndromeIdiopathic pulmonary fibrosis: treatment update.The role of macrophages in healing the wounded lung.Coagulation cascade proteinases in lung injury and fibrosis.TGF-β: Titan of Lung Fibrogenesis.The epithelium in idiopathic pulmonary fibrosis: breaking the barrier.Recent advances in understanding the pathogenesis of scleroderma-interstitial lung disease.Promising new treatment targets in patients with fibrosing lung disorders.Thrombin induces epithelial-mesenchymal transition via PAR-1, PKC, and ERK1/2 pathways in A549 cells.Interferon-γ and tumor necrosis factor-α act synergistically to up-regulate tissue factor in alveolar epithelial cells.Protease-activated receptor-2 induces myofibroblast differentiation and tissue factor up-regulation during bleomycin-induced lung injury: potential role in pulmonary fibrosis.
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P2860
Procoagulant signalling mechanisms in lung inflammation and fibrosis: novel opportunities for pharmacological intervention?
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Procoagulant signalling mechan ...... pharmacological intervention?
@ast
Procoagulant signalling mechan ...... pharmacological intervention?
@en
type
label
Procoagulant signalling mechan ...... pharmacological intervention?
@ast
Procoagulant signalling mechan ...... pharmacological intervention?
@en
prefLabel
Procoagulant signalling mechan ...... pharmacological intervention?
@ast
Procoagulant signalling mechan ...... pharmacological intervention?
@en
P2860
P356
P1476
Procoagulant signalling mechan ...... pharmacological intervention?
@en
P2093
R C Chambers
P2860
P304
P356
10.1038/SJ.BJP.0707603
P407
P478
153 Suppl 1
P577
2008-01-28T00:00:00Z