Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy.
about
Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens.Driving gene-engineered T cell immunotherapy of cancer.The Principles of Engineering Immune Cells to Treat Cancer.Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.Interpreting T-Cell Cross-reactivity through Structure: Implications for TCR-Based Cancer Immunotherapy.Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes.Emerging Concepts in TCR Specificity: Rationalizing and (Maybe) Predicting Outcomes.CRISPR-mediated TCR replacement generates superior anticancer transgenic T cells.Current Strategies to Enhance Anti-Tumour Immunity.General Prediction of Peptide-MHC Binding Modes Using Incremental Docking: A Proof of Concept.Soluble T-cell receptor design influences functional yield in an E. coli chaperone-assisted expression system.Preclinical Strategies to Identify Off-Target Toxicity of High-Affinity TCRs.
P2860
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P2860
Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
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2016年學術文章
@zh-hant
name
Direct molecular mimicry enabl ...... gned for cancer immunotherapy.
@ast
Direct molecular mimicry enabl ...... gned for cancer immunotherapy.
@en
type
label
Direct molecular mimicry enabl ...... gned for cancer immunotherapy.
@ast
Direct molecular mimicry enabl ...... gned for cancer immunotherapy.
@en
prefLabel
Direct molecular mimicry enabl ...... gned for cancer immunotherapy.
@ast
Direct molecular mimicry enabl ...... gned for cancer immunotherapy.
@en
P2093
P2860
P356
P1433
P1476
Direct molecular mimicry enabl ...... igned for cancer immunotherapy
@en
P2093
Annelise Vuidepot
Bent K Jakobsen
Emma Baston
Emma Hickman
Gabrielle S Le Provost
Giovanna Bossi
Joseph Dukes
Malkit Sami
Marine C C Raman
Namir Hassan
P2860
P2888
P356
10.1038/SREP18851
P407
P577
2016-01-13T00:00:00Z