C/EBPγ deregulation results in differentiation arrest in acute myeloid leukemia.
about
MEIS1-mediated transactivation of synaptotagmin-like 1 promotes CXCL12/CXCR4 signaling and leukemogenesis.EVI2B is a C/EBPα target gene required for granulocytic differentiation and functionality of hematopoietic progenitors.Sox4 is a key oncogenic target in C/EBPα mutant acute myeloid leukemiaDisruption of the C/EBPα-miR-182 balance impairs granulocytic differentiation.AMPA-receptor specific biogenesis complexes control synaptic transmission and intellectual ability.Gene network-based analysis identifies two potential subtypes of small intestinal neuroendocrine tumors.Genome-Scale CRISPR-Mediated Control of Gene Repression and ActivationThe multifaceted functions of C/EBPα in normal and malignant haematopoiesis.Granulopoiesis requires increased C/EBPα compared to monopoiesis, correlated with elevated Cebpa in immature G-CSF receptor versus M-CSF receptor expressing cells.The +37 kb Cebpa Enhancer Is Critical for Cebpa Myeloid Gene Expression and Contains Functional Sites that Bind SCL, GATA2, C/EBPα, PU.1, and Additional Ets Factors.In Vivo Deletion of the Cebpa +37 kb Enhancer Markedly Reduces Cebpa mRNA in Myeloid Progenitors but Not in Non-Hematopoietic Tissues to Impair Granulopoiesis.C/EBPγ Is a Critical Regulator of Cellular Stress Response Networks through Heterodimerization with ATF4C/EBPγ suppresses senescence and inflammatory gene expression by heterodimerizing with C/EBPβAn autonomous CEBPA enhancer specific for myeloid-lineage priming and neutrophilic differentiation.The human nucleophosmin 1 mutation A inhibits myeloid differentiation of leukemia cells by modulating miR-10b.B-cell precursor acute lymphoblastic leukemia with isolated t(14;19)(q32;q13) abnormality involving the CEBPG gene.C/EBPα in normal and malignant myelopoiesis.Pharmacological inhibition of fatty-acid oxidation synergistically enhances the effect of l-asparaginase in childhood ALL cells.CEBPA-CEBPG axis as a novel promising therapeutic target in acute myeloid leukemia.5azadC treatment upregulates miR-375 level and represses HPV16 E6 expression.ZNF143 protein is an important regulator of the myeloid transcription factor C/EBPα.CREB engages C/EBPδ to initiate leukemogenesis.
P2860
Q27331832-6EA2EC6D-9DBC-49C6-8910-A498FAED4229Q33112273-F7810CA0-0A3B-49BC-97E4-BAB16BFD4112Q33686199-79828486-59BE-46AC-82FC-79FBFDF1CF56Q33854384-3F791546-C341-4D95-BA69-86C9DEE85E09Q33882277-93325BAE-B470-4E03-954B-10EFA55D7C82Q34012005-36B2945A-ACE9-4BA1-A405-F59030A17372Q34443093-8F7CA519-EF39-4733-9E51-36024AA21EEBQ34502869-423E8B20-DFA0-4E0B-A186-9519ECCD3499Q35154153-4B2A68B5-5D3F-4A28-8733-D9AEF81194A3Q35566633-7F6D9892-44A9-43B1-B514-8651C9C7409FQ35944184-B417D846-6A70-4A2F-936B-8E22E12DCDCCQ36597272-9994E5DE-F1A5-4E30-A1C7-8FD9A7789C7CQ37122948-837DE7DB-F58B-4FCE-89BC-E575C8360583Q37299008-5CB9B6F7-E071-40E8-B850-BFFDE31D21C8Q37687642-8E7EE677-C375-4138-A851-A05DD180B5B2Q38351297-E8A9FDDF-28E9-4533-8C7B-5905773F645FQ38370875-5651FB9C-1BFF-4C8C-B073-3FAE2FD3586CQ38846668-F0884CB2-CC45-4758-86DF-74BCBDE32552Q39286221-4CFFE67C-099A-45E1-AC53-3302927E67C1Q40196443-9F3D379E-648C-415C-9A2F-5D82AF969399Q47814357-139A767C-845A-4324-A5DC-7AE4289E68F5Q52671045-1C2CF47D-6AEC-4845-A22E-163C90E4942E
P2860
C/EBPγ deregulation results in differentiation arrest in acute myeloid leukemia.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
C/EBPγ deregulation results in differentiation arrest in acute myeloid leukemia.
@ast
C/EBPγ deregulation results in differentiation arrest in acute myeloid leukemia.
@en
type
label
C/EBPγ deregulation results in differentiation arrest in acute myeloid leukemia.
@ast
C/EBPγ deregulation results in differentiation arrest in acute myeloid leukemia.
@en
prefLabel
C/EBPγ deregulation results in differentiation arrest in acute myeloid leukemia.
@ast
C/EBPγ deregulation results in differentiation arrest in acute myeloid leukemia.
@en
P2093
P2860
P356
P1476
C/EBPγ deregulation results in differentiation arrest in acute myeloid leukemia
@en
P2093
Alexander K Ebralidze
Annalisa Di Ruscio
Ari Melnick
Bas Wouters
Clara Shapiro-Koss
Giovanni Amabile
Hanna S Radomska
Hong Zhang
Irene Lowers
Junyan Zhang
P2860
P304
P356
10.1172/JCI65102
P407
P577
2012-11-19T00:00:00Z