An autonomous CEBPA enhancer specific for myeloid-lineage priming and neutrophilic differentiation.
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RUNX1-ETO and RUNX1-EVI1 Differentially Reprogram the Chromatin Landscape in t(8;21) and t(3;21) AML.A CRISPR Path to Engineering New Genetic Mouse Models for Cardiovascular ResearchThe potential of a single enhancerComprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms.Enhancers and their dynamics during hematopoietic differentiation and emerging strategies for therapeutic action.Transcriptional determination and functional specificity of myeloid cells: making sense of diversity.C/EBPα deregulation as a paradigm for leukemogenesis.Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers.CRISPR-based strategies for studying regulatory elements and chromatin structure in mammalian gene control.ZNF143 protein is an important regulator of the myeloid transcription factor C/EBPα.NR4A1 and NR4A3 restrict HSC proliferation via reciprocal regulation of C/EBPα and inflammatory signaling.Potential for subsets of wt-NPM1 primary AML blasts to respond to retinoic acid treatment.
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An autonomous CEBPA enhancer specific for myeloid-lineage priming and neutrophilic differentiation.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 10 March 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
An autonomous CEBPA enhancer s ...... neutrophilic differentiation.
@en
An autonomous CEBPA enhancer s ...... neutrophilic differentiation.
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type
label
An autonomous CEBPA enhancer s ...... neutrophilic differentiation.
@en
An autonomous CEBPA enhancer s ...... neutrophilic differentiation.
@nl
prefLabel
An autonomous CEBPA enhancer s ...... neutrophilic differentiation.
@en
An autonomous CEBPA enhancer s ...... neutrophilic differentiation.
@nl
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P2860
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An autonomous CEBPA enhancer s ...... neutrophilic differentiation.
@en
P2093
Claudia Erpelinck
Claudia Gebhard
Dominik Beck
Elwin Rombouts
Eric Bindels
Hans de Looper
Harmen J G van de Werken
John Pimanda
Kirsten van Lom
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P304
P356
10.1182/BLOOD-2016-01-695759
P407
P50
P577
2016-03-10T00:00:00Z