Role of pregnane X receptor in control of all-trans retinoic acid (ATRA) metabolism and its potential contribution to ATRA resistance.
about
Retinoid-xenobiotic interactions: the Ying and the YangRole of pregnane X receptor in chemotherapeutic treatmentAltered retinoic acid metabolism in diabetic mouse kidney identified by O isotopic labeling and 2D mass spectrometry.Pregnane X Receptor (PXR) expression in colorectal cancer cells restricts irinotecan chemosensitivity through enhanced SN-38 glucuronidation.Elucidating the 'Jekyll and Hyde' nature of PXR: the case for discovering antagonists or allosteric antagonists.Overcoming drug resistance by regulating nuclear receptors.Identification of pregnane X receptor ligands using time-resolved fluorescence resonance energy transfer and quantitative high-throughput screening.Induction of CYP26A1 by metabolites of retinoic acid: evidence that CYP26A1 is an important enzyme in the elimination of active retinoidsRegulation of hepatic ABCC transporters by xenobiotics and in disease states.Expression of the PXR gene in various types of cancer and drug resistancePXR: a xenobiotic receptor of diverse function implicated in pharmacogenetics.Nuclear receptor PXR, transcriptional circuits and metabolic relevance.Pregnane X receptor polymorphisms associated with human diseases.Pharmacogenetics of the nuclear hormone receptors: the missing link between environment and drug effects?Nuclear receptors and drug metabolism for the personalization of cancer therapy.Pregnane X receptor, constitutive androstane receptor and hepatocyte nuclear factors as emerging players in cancer precision medicine.The aldo-keto reductase Akr1b7 gene is a common transcriptional target of xenobiotic receptors pregnane X receptor and constitutive androstane receptor.
P2860
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P2860
Role of pregnane X receptor in control of all-trans retinoic acid (ATRA) metabolism and its potential contribution to ATRA resistance.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
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@zh
2007年學術文章
@zh-hant
name
Role of pregnane X receptor in ...... ntribution to ATRA resistance.
@ast
Role of pregnane X receptor in ...... ntribution to ATRA resistance.
@en
type
label
Role of pregnane X receptor in ...... ntribution to ATRA resistance.
@ast
Role of pregnane X receptor in ...... ntribution to ATRA resistance.
@en
prefLabel
Role of pregnane X receptor in ...... ntribution to ATRA resistance.
@ast
Role of pregnane X receptor in ...... ntribution to ATRA resistance.
@en
P2093
P2860
P356
P1476
Role of pregnane X receptor in ...... ontribution to ATRA resistance
@en
P2093
Frank J Gonzalez
Kristopher W Krausz
Xiaochao Ma
P2860
P304
P356
10.1124/JPET.107.131045
P407
P50
P577
2007-10-25T00:00:00Z