CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity. - Wikidata - wikimedia - TriplyDB

CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity.

CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity.

http://www.wikidata.org/entity/Q36498454

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Targeting Homeostatic T Cell Proliferation to Control Beta-Cell Autoimmunity Lymphopenia-induced proliferation in aire-deficient mice helps to explain their autoimmunity and differences from human patients PD-L1 regulates the development, maintenance, and function of induced regulatory T cells Increased numbers of IL-7 receptor molecules on CD4+CD25-CD107a+ T-cells in patients with autoimmune diseases affecting the central nervous system.Modulating T-cell homeostasis with IL-7: preclinical and clinical studies.Ageing combines CD4 T cell lymphopenia in secondary lymphoid organs and T cell accumulation in gut associated lymphoid tissue.ERK-dependent T cell receptor threshold calibration in rheumatoid arthritis.IL-2 mediates CD4+ T cell help in the breakdown of memory-like CD8+ T cell tolerance under lymphopenic conditions Mislocalization of SLP-76 leads to aberrant inflammatory cytokine and autoantibody production Metabolic regulation in progression to autoimmune diabetes Redirecting the immune response: role of adoptive T cell therapy.Expression level of a pancreatic neo-antigen in beta cells determines degree of diabetes pathogenesis.IL-18 synergizes with IL-7 to drive slow proliferation of naive CD8 T cells by costimulating self-peptide-mediated TCR signals.Th1-driven immune reconstitution disease in Mycobacterium avium-infected mice.Immune aging and autoimmunity.Innate immune signaling induces interleukin-7 production from salivary gland cells and accelerates the development of primary Sjögren's syndrome in a mouse model Premature CD4+ T cell aging and its contribution to lymphopenia-induced proliferation of memory cells in autoimmune-prone non-obese diabetic mice Altered naive and memory CD4+ T-cell homeostasis and immunosenescence characterize younger patients with myelodysplastic syndrome Increased Blood Levels of Growth Factors, Proinflammatory Cytokines, and Th17 Cytokines in Patients with Newly Diagnosed Type 1 Diabetes.Children with islet autoimmunity and enterovirus infection demonstrate a distinct cytokine profile IL-7 receptor α blockade, an off-switch for autoreactive T cells.Anti-IL-7 receptor-α reverses established type 1 diabetes in nonobese diabetic mice by modulating effector T-cell function.Selective Granulocyte and Monocyte Apheresis as a Non-Pharmacological Option for Patients with Inflammatory Bowel Disease.Signaling pathways in aged T cells - a reflection of T cell differentiation, cell senescence and host environment.Immunosuppression in islet transplantation IL-7- and IL-15-mediated TCR sensitization enables T cell responses to self-antigens.Soluble IL7Rα potentiates IL-7 bioactivity and promotes autoimmunity.The janus head of T cell aging - autoimmunity and immunodeficiency.CD40L+ CD4+ memory T cells migrate in a CD62P-dependent fashion into reactive lymph nodes and license dendritic cells for T cell priming Memory-like CD8+ and CD4+ T cells cooperate to break peripheral tolerance under lymphopenic conditions.Concentration and activity of the soluble form of the interleukin-7 receptor α in type 1 diabetes identifies an interplay between hyperglycemia and immune function.Interleukin-7 enhances the Th1 response to promote the development of Sjögren's syndrome-like autoimmune exocrinopathy in mice An essential role of the Forkhead-box transcription factor Foxo1 in control of T cell homeostasis and tolerance.Developments in the scientific understanding of rheumatoid arthritis.L-selectin: role in regulating homeostasis and cutaneous inflammation.Suppressors of cytokine signaling (SOCS) in T cell differentiation, maturation, and function.Tumor immune therapy: lessons from infection and implications for cancer - can IL-7 help overcome immune inhibitory networks?Interleukin-7 and type 1 diabetes.Recurrence of autoimmunity in pancreas transplant patients: research update.Targeting memory T cells in type 1 diabetes.

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CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity.

http://www.wikidata.org/entity/Q36498454

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

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2008年學術文章

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name

CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity.

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CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity.

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type

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CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity.

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CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity.

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prefLabel

CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity.

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CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity.

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Proceedings of the National Academy of Sciences of the United States of America

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CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity.

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Albert Lin

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Alisha R Elford

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Arda Shahinian

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Kristine M Garza

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Tak W Mak

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P2860

Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells

Adjuvant IL-7 or IL-15 overcomes immunodominance and improves survival of the CD8+ memory cell pool.

IL-1alpha, IL-1beta, and IFN-gamma mark beta cells for Fas-dependent destruction by diabetogenic CD4(+) T lymphocytes

Homeostatic expansion of T cells during immune insufficiency generates autoimmunity.

Requirement for CD4 T cell help in generating functional CD8 T cell memory.

Multiple pathways to induction of virus-induced autoimmune demyelination: lessons from Theiler's virus infection.

Cognate CD4(+) T cell licensing of dendritic cells in CD8(+) T cell immunity.

High-dose cyclophosphamide for aplastic anemia and autoimmunity.

T-cell signalling and autoimmunity: molecular mechanisms of disease.

TNF-alpha is critical for antitumor but not antiviral T cell immunity in mice.

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105

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Pamela S Ohashi

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5565094

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18287017

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2268574

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