about
Lentiviral transduction of dendritic cells confers protective antiviral immunity in vivoLoss of the signaling adaptor TRAF1 causes CD8+ T cell dysregulation during human and murine chronic infectionTNF-alpha is critical for antitumor but not antiviral T cell immunity in mice.Two Antagonistic MALT1 Auto-Cleavage Mechanisms Reveal a Role for TRAF6 to Unleash MALT1 Activation.Exposure to sequestered self-antigens in vivo is not sufficient for the induction of autoimmune diabetes.Vav1 GEF activity is required for T cell mediated allograft rejectionCD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity.Highly reduced binding to high and low affinity mouse Fc gamma receptors by L234A/L235A and N297A Fc mutations engineered into mouse IgG2a.Improved cancer immunotherapy by a CD25-mimobody conferring selectivity to human interleukin-2.Partial deficiency of sphingosine-1-phosphate lyase confers protection in experimental autoimmune encephalomyelitisHoming phenotypes of tumor-specific CD8 T cells are predetermined at the tumor site by crosspresenting APCs.Deficiency of MALT1 paracaspase activity results in unbalanced regulatory and effector T and B cell responses leading to multiorgan inflammation.IRAK-4 kinase activity is required for IRAK-4-dependent innate and adaptive immune responses.Aggravation of viral hepatitis by platelet-derived serotonin.Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies.Cutting edge: cross-presentation as a mechanism for efficient recruitment of tumor-specific CTL to the brain.The T-cell fingerprint of MALT1 paracaspase revealed by selective inhibition.Selective MALT1 paracaspase inhibition does not block TNF-α production downstream of TLR4 in myeloid cells.Loss of Fas (CD95/APO-1) expression by antigen-specific cytotoxic T cells is reversed by inhibiting DNA methylation.Peripheral tolerance limits CNS accumulation of CD8 T cells specific for an antigen shared by tumor cells and normal astrocytes.A Critical Role for the Innate Immune Signaling Molecule IRAK-4 in T Cell ActivationIL-7 Engages Multiple Mechanisms to Overcome Chronic Viral Infection and Limit Organ PathologyT-cell immune responses in the brain and their relevance for cerebral malignanciesThe brain parenchyma is permissive for full antitumor CTL effector function, even in the absence of CD4 T cellsEfficient induction of CD8 T-associated immune protection by vaccination with mRNA transfected dendritic cellsMalt1 Protease Deficiency in Mice Disrupts Immune Homeostasis at Environmental Barriers and Drives Systemic T Cell-Mediated Autoimmunity
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description
researcher
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wetenschapper
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հետազոտող
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name
T Calzascia
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T Calzascia
@en
T Calzascia
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T Calzascia
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T Calzascia
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T Calzascia
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T Calzascia
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T Calzascia
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T Calzascia
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T Calzascia
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T Calzascia
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T Calzascia
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P106
P31
P496
0000-0001-8225-6744