Microtubule-associated protein/microtubule affinity-regulating kinase 4 (MARK4) is a negative regulator of the mammalian target of rapamycin complex 1 (mTORC1).
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MARK4 regulates NLRP3 positioning and inflammasome activation through a microtubule-dependent mechanismPolarized activities of AMPK and BRSK in primary hippocampal neurons.Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel autophagy regulator by high content shRNA screening.Mark4 promotes oxidative stress and inflammation via binding to PPARγ and activating NF-κB pathway in mice adipocytes.iLIR database: A web resource for LIR motif-containing proteins in eukaryotes.Mammalian target of rapamycin signaling in cardiac physiology and disease.AMPK: a contextual oncogene or tumor suppressor?The kinase triad, AMPK, mTORC1 and ULK1, maintains energy and nutrient homoeostasis.The importance of autophagy in cardioprotection.Transcriptional regulation of the stress response by mTOR.Lysosomal recruitment of TSC2 is a universal response to cellular stressRegulation of microtubule (MT)-based cytoskeleton in the seminiferous epithelium during spermatogenesisTSC2 mediates hyperosmotic stress-induced inactivation of mTORC1.Elucidation of Dietary Polyphenolics as Potential Inhibitor of Microtubule Affinity Regulating Kinase 4: In silico and In vitro Studies.Identification of a multi-cancer gene expression biomarker for cancer clinical outcomes using a network-based algorithm.Mark4 promotes adipogenesis and triggers apoptosis in 3T3-L1 adipocytes by activating JNK1 and inhibiting p38MAPK pathways.PtdIns3P controls mTORC1 signaling through lysosomal positioning.Evaluation of human microtubule affinity-regulating kinase 4 inhibitors: fluorescence binding studies, enzyme, and cell assays.Transcriptome and DNA Methylome Analysis in a Mouse Model of Diet-Induced Obesity Predicts Increased Risk of Colorectal Cancer.The structural analysis of MARK4 and the exploration of specific inhibitors for the MARK family: a computational approach to obstruct the role of MARK4 in prostate cancer progression.Human microtubule affinity-regulating kinase 4 is stable at extremes of pH.
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P2860
Microtubule-associated protein/microtubule affinity-regulating kinase 4 (MARK4) is a negative regulator of the mammalian target of rapamycin complex 1 (mTORC1).
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Microtubule-associated protein ...... rapamycin complex 1 (mTORC1).
@ast
Microtubule-associated protein ...... rapamycin complex 1 (mTORC1).
@en
type
label
Microtubule-associated protein ...... rapamycin complex 1 (mTORC1).
@ast
Microtubule-associated protein ...... rapamycin complex 1 (mTORC1).
@en
prefLabel
Microtubule-associated protein ...... rapamycin complex 1 (mTORC1).
@ast
Microtubule-associated protein ...... rapamycin complex 1 (mTORC1).
@en
P2860
P356
P1476
Microtubule-associated protein ...... rapamycin complex 1 (mTORC1).
@en
P2093
P2860
P304
P356
10.1074/JBC.C112.396903
P407
P577
2012-11-26T00:00:00Z